Biogen

NCT01863069

Avonex®: Safety, Blood Levels and Effects

NCT00031083

Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas

NCT00046488

Safety and Efficacy of IDEC-152 in the Treatment of Chronic Lymphocytic Leukemia (CLL)

NCT00913250

A Bioequivalence Study of Serum Free Avonex and Serum Containing Avonex in Healthy Volunteers

NCT00186589

90Y-IBRITUMOMAB Tiuxetan and AHCI With HD Chemotherapy and Autologous Transplantation for Relapsed or Resistant NHL

NCT00105170

Safety and Tolerability of hCBE-11 in Subjects With Advanced Solid Tumors

NCT00319930

Phase 1, Dose-Escalation, Pharmacodynamic Study of IV CNF1010 in ZAP-70 Positive CLL

NCT00526812

A Safety Study of RTA 744 in Patients With Recurrent High-Grade Gliomas

NCT00344786

Phase 1, Dose-Escalation Study of Oral CNF2024(BIIB021) in CLL

NCT00345189

Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors

NCT00299962

Gene Therapy for Pleural Malignancies

NCT00529438

RTA 402 in Patients With Advanced Solid Tumors or Lymphoid Malignancies

NCT00527410

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis

NCT00476515

Rituximab Therapy for Patients on Kidney Transplant Waiting List With Positive Donor Specific Crossmatch to Living Donor

NCT00488566

GSK Drug Single Dose Escalation And Their Effect On Resting Motor Threshold In Healthy Volunteers

NCT00529113

Study With Gemcitabine and RTA 402 for Patients With Unresectable Pancreatic Cancer

NCT00531193

Using PET Scans to Study Brain Receptor Occupancy of BIIB014 in Healthy Male Volunteers

NCT00559702

Safety Study of Natalizumab to Treat Multiple Sclerosis (MS)

NCT00412412

CNF2024 (BIIB021) HER2- (QD) HER2+ (BIW w/Herceptin) PK/PD Study

NCT00555724

Phase 1 Study of BIIB022 (Anti-IGF-1R Monoclonal Antibody) in Relapsed/Refractory Solid Tumors

NCT00618735

Once or Twice Daily Administration of BIIB021 to Subjects With Advanced Solid Tumors

NCT02125578

A Multiple Dose Safety Study of PEG-IFN in Healthy Volunteers

NCT00908154

Safety, Tolerability and Pharmacokinetics of Repeat Doses of GSK1014802.

NCT00675701

A Study to Define the ECG Effects of Lixivaptan Compared to Placebo and Moxifloxacin in Healthy Adult Men and Women: A Thorough ECG Study

NCT00674947

A Phase I Study of BIIB015 in Relapsed/Refractory Solid Tumors

NCT00725933

Administration of BIIB028 to Subjects With Solid Tumors

NCT00651443

Mechanism of Action of Galiximab in Subjects With Previously Untreated Follicular Non-Hodgkin's Lymphoma

NCT00771329

BIIB023 (Anti-TWEAK) in Subjects With Rheumatoid Arthritis

NCT00837785

A 24-Hour Pharmacokinetic Determination of BG00012 After Single-Day Oral Administration in Subjects With MS

NCT00858156

BG9928 in Subjects With Hepatic Impairment

NCT00955396

Study to Investigate the Effect of GSK1014802 on Ambulatory Blood Pressure

NCT00964288

Effect of GSK1014802 on Electrical Hyperalgesia and Threshold Tracking in Healthy Subjects

NCT00956436

Sorafenib With BIIB022 in Hepatocellular Carcinoma (HCC)

NCT00961766

Evaluate the Safety, Tolerability and Pharmacokinetics of BG00010 (Neublastin) Administered to Sciatica Participants

NCT00970580

A Study of BIIB022 in Combination With Paclitaxel and Carboplatin in Subjects With Non-Small Cell Lung Cancer

NCT01069913

Pharmacokinetics Profile Study of BG00012 Standard Formulation and BG00012 Active Pharmaceutical Ingredient

NCT01017666

BIIB014 Effects on the Pharmacokinetics (PK) of Rosiglitazone, Warfarin, and Midazolam

NCT01017198

Effect of Food and Antacid on BIIB021 With Advanced Solid Tumors

NCT01035515

BIIB014 Cardiovascular Monitoring Study

NCT01132703

Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers

NCT01052506

BIIB033 Single Ascending Dose Study in Healthy Volunteer Subjects

NCT01119677

A Study of Avonex to Determine the Effects of Dose Titration on the Incidence of Flu Like Symptoms in Healthy Volunteers

NCT01119781

A Single-Dose, Pharmacokinetic/Pharmacodynamic (PK/PD), & Safety Study of BIIB017 in Participants With Renal Impairment & Healthy Volunteers

NCT01159483

First-in-Human Study of PF-04958242 in Healthy Volunteers

NCT01215084

A Pharmacokinetics (PK) and Safety Study of Oral Fampridine-PR 10 mg in Chinese, Japanese, and Caucasian Adult Healthy Volunteers

NCT01244139

Safety Study of BIIB033 in Subjects With Multiple Sclerosis

NCT01238679

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of PF-04958242 in Healthy Adult Volunteers

NCT01281111

Alternate Dosing Regimens of BG00012 in Healthy Volunteers

NCT01313364

A Safety Study in Healthy Volunteers of the Single-Use Autoinjector Containing Placebo of BG9418 Interferon Beta-1a With a 25-Gauge × 1-Inch Needle

NCT01365338

A Study To Assess Effects Of PF-04958242 On Bold Functional Magnetic Resonance Imaging During Working Memory Activation And Arterial Spin Labeling At Rest In Healthy Subjects

NCT01397539

Single Ascending Dose Study of BIIB037 in Participants With Alzheimer's Disease

NCT01511510

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Repeated Doses of PF-04958242 in Healthy Volunteers

NCT01405833

Study of the Safety, Tolerability, Pharmacokinetics and Safety of BG00010 (Neublastin) in Subjects With Sciatica.

NCT01416207

A Multiple-Dose, Open-Label, Phase 1, Pharmacokinetic, Pharmacodynamic, and Safety Study of Avonex® in Chinese Healthy Volunteer Subjects

NCT01420458

Study in Healthy Volunteers to Establish the BioEquivalence of Two Formulations of BG00012

NCT01424163

Dexpramipexole Japanese PK Study

NCT01407406

Phase 1 Study to Evaluate the PK, Safety, Tolerability of BIIB023 in Chinese, Japanese, and Caucasian Healthy Volunteers

NCT01461161

A Single-Dose, Open-Label, Randomized, Food Effect and Blinded, Randomized, Dose Proportionality Study in Healthy Volunteers With Bardoxolone Methyl

NCT01494701

An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA)

NCT01518894

A Study To Examine The Safety, Tolerability And Pharmacokinetics Of PF-04958242 In Psychiatrically Stable Subjects With Schizophrenia

NCT01503866

A Phase I Study to Investigate the Absorption, Metabolism and Excretion in Healthy Male Subjects

NCT01518920

A Study Of The Effects Of PF-04958242 In Subjects With Age-Related Hearing Loss

NCT01453426

Phase 1 Study to Evaluate the PK, Safety, and Tolerability of BG00012 in Chinese, Japanese, and Caucasian Healthy Volunteers

NCT01500408

Demonstrate the Bioequivalence of Interferon Beta-1a (INFB) Manufactured by Two Different Processes in Healthy Volunteers

NCT01500798

A Pharmacodynamic Study of Measured Glomerular Filtration Rate in Patients With Chronic Kidney Disease and Type 2 Diabetes

NCT01549769

Pharmacokinetic and Pharmacodynamic Study of Bardoxolone Methyl in Patients With Chronic Kidney Disease and Type 2 Diabetes

NCT01551446

Pilot Assessment of the Effects of Bardoxolone Methyl on Renal Perfusion, Systemic Haemodynamics and Cardiac Function in Patients With Chronic Kidney Disease and Type 2 Diabetes

NCT01563562

Single-Dose, Open-Label Pharmacokinetic Study of Bardoxolone Methyl in Subjects With Mild, Moderate, and Severe Hepatic Impairment and Normal Hepatic Function

NCT01598363

An Open-Label Study of the Effect of Bardoxolone Methyl on the Single Dose Pharmacokinetics of Digoxin and Rosuvastatin in Healthy Volunteers

NCT01610310

Peginterferon Beta-1a (BIIB017) Autoinjector Pharmacokinetic Study in Healthy Volunteers

NCT01632449

Study in Healthy Volunteers to Establish the Bioequivalence of Two Different Manufacturers.

NCT01646840

Study Of The PF-04958242 Blood Concentrations Of A Capsule Formulation Of PF-04958242 Compared To A Solution Formulation

NCT01689116

Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers

NCT01677572

Multiple Dose Study of Aducanumab (BIIB037) (Recombinant, Fully Human Anti-Aβ IgG1 mAb) in Participants With Prodromal or Mild Alzheimer's Disease

NCT01749098

A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers

NCT01780246

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701)

NCT01764594

Safety Study of CDP7657 in Patients With Systemic Lupus Erythematosus

NCT01842126

Phase 1 Subcutaneous Single and Multiple Ascending Dose Study of BG00010 (Neublastin)

NCT01884935

PK and PD Study of Natalizumab in Pediatric Subjects With RRMS

NCT01915901

PeptoBismol® Use to Reduce Gastrointestinal Events in Healthy Volunteers Receiving DMF [Tecfidera®] Twice Daily

NCT01924832

BG00012 Regional Absorption Study

NCT01929746

Daclizumab Japanese PK Study

NCT01943513

A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers

NCT01978652

Pharmacokinetic Study of Peginterferon Beta-1a in Japanese and Caucasian Adult Healthy Participants.

NCT02029716

RTA 408 Lotion in Healthy Volunteers

NCT02029729

RTA 408 in the Treatment of Advanced Solid Tumors (NSCLC & Melanoma) - DISCOVER

NCT02071121

Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB061 in Healthy Adult Volunteers Including Absolute Bioavailability and Food Effect

NCT02052791

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246)

NCT02106897

Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Single Doses and Multiple Doses of BIIB059 (Litifilimab) in Healthy Volunteers and Participants With Systemic Lupus Erythematosus

NCT02171208

A Healthy Volunteer Study to Establish the Bioequivalence of BG00012 Supplied by 2 Different Commercial Manufacturers

NCT02201849

A Study of ALKS 8700, a Monomethyl Fumarate (MMF) Molecule, in Healthy Adults

NCT02228707

Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB061 in Healthy Adult Volunteers

NCT02228395

Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Doses Of PF-04958242 In Healthy Volunteers

NCT02269930

Study to Evaluate the Pharmacokinetic Profiles of BIIB017 (Peginterferon Beta-1a) and Rebif® (Interferon Beta-1a) in Healthy Volunteers

NCT02294851

A Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study of Intravenously Administered BMS-986168 in Healthy Subjects

NCT02332798

Multiple Ascending Doses of PF-04958242 in Subjects With Stable Schizophrenia

NCT02359344

PK & Tolerability of CNV1014802 in Young and Elderly Healthy Volunteers

NCT02341482

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of PF-04958242 in Healthy Subjects

NCT02551497

Study to Evaluate the Interaction Between a Drug and CNV1014802 in Healthy Subjects

NCT02443740

Safety, Tolerability and Pharmacokinetics of BIIB118 (PF-05251749)

NCT02434718

Single and Multiple Ascending Dose Study of Aducanumab (BIIB037) in Japanese Participants With Alzheimer's Disease

NCT02459886

Single-Ascending Dose Study of BIIB054 in Healthy Participants and Early Parkinson's Disease

NCT02521545

Single-Dose Study of a New Formulation of BIIB061

NCT02555085

Single Ascending Doses of BIIB063 in Healthy Volunteers

NCT02460094

Multiple Ascending Dose Study of Intravenously Administered BMS-986168 (BIIB092) in Patients With Progressive Supranuclear Palsy

NCT02658916

Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003

NCT02641041

Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of BIIB033 in Healthy Japanese Participants

NCT02698267

Effect of Itraconazole on the Pharmacokinetics of BIIB074

NCT02691702

Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers

NCT02751905

Absorption, Metabolism, and Excretion Study of BIIB074

NCT02782975

Absolute Bioavailability of a Single, Fixed Subcutaneous Dose of Aducanumab in Healthy Participants

NCT02833142

Pharmacokinetics, Safety and Tolerability of Single Doses of BIIB033 (Opicinumab) Produced by 2 Manufacturing Processes

NCT02829541

A Phase 1, Single-Ascending-Dose, Safety, Tolerability, Pharmacokinetic(PK), and Pharmacodynamic(PD) Study of BIIB068 in Healthy Participants

NCT02831517

PK and Safety Study of BIIB074 in Healthy Japanese and Caucasian Participants

NCT02951221

New Formulation and Food Effect Study of BIIB074

NCT02981082

Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension

NCT02666963

A Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of RTA 901 in Healthy Adults

NCT03056729

Single-Ascending-Dose Study of BIIB076 in Healthy Volunteers and Participants With Alzheimer's Disease

NCT03385525

Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074

NCT03284931

A Study to Assess the Pharmacodynamic Effects of SAGE-217 in Healthy Adults Using an Insomnia Model

NCT03224793

Safety, Tolerability, and Pharmacokinetics of Single Doses of BIIB059 in Healthy Japanese Subjects.

NCT03264079

Effect of Itraconazole on the Pharmacokinetics of Bardoxolone Methyl in Healthy Adults

NCT03324685

A Drug Interaction Study of BIIB074 and an Oral Contraceptive Regimen

NCT03454126

Evaluating the Safety, Tolerability, and Pharmacokinetics of BIIB095 in Healthy Participants

NCT03579030

Safety and PK/PD of RTA 1701 in Healthy Adults

NCT03626012

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

NCT03664453

A Pharmacokinetic Study of Omaveloxolone in Healthy Volunteers

NCT03764488