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Clinical Trials Directory
Explore 1,747 clinical trials worldwide
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Showing 1-50 of 1,747 trials
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Phase: Early Phase 1
Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Clinical Trials (1,747)
NCT03590821
Timed Aspirin Chronobiome Study
EARLY_PHASE1
Not yet recruiting
60 participants
Started: Dec 31, 2026 · Completed: May 31, 2028
1 condition
1 sponsor
1 location
NCT06825143
Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury
EARLY_PHASE1
Not yet recruiting
68 participants
Started: Oct 1, 2026 · Completed: Jun 30, 2030
5 conditions
1 sponsor
1 location
NCT07107659
Safety and Efficacy of ONT01 in Lupus
EARLY_PHASE1
Not yet recruiting
61 participants
Started: Sep 4, 2026 · Completed: May 31, 2030
8 conditions
2 sponsors
1 location
NCT06602076
Developing Empowering Smoking Cessation
EARLY_PHASE1
Not yet recruiting
50 participants
Started: Aug 31, 2026 · Completed: Jul 31, 2027
1 condition
2 sponsors
0 locations
NCT07218653
Sex-Specific Cerebrovascular Dysfunction in Metabolic Syndrome-Role of COX
EARLY_PHASE1
Not yet recruiting
72 participants
Started: Jul 31, 2026 · Completed: Jul 31, 2031
1 condition
2 sponsors
0 locations
NCT06758596
Research Investigating Drug Effects-2 (RiDE-2)
EARLY_PHASE1
Not yet recruiting
144 participants
Started: Jul 15, 2026 · Completed: Jun 30, 2031
3 conditions
1 sponsor
1 location
NCT07121127
Effect of Fu's Subcutaneous Needling for Age-related Macular Degeneration
EARLY_PHASE1
Not yet recruiting
38 participants
Started: Jul 7, 2026 · Completed: Mar 9, 2030
1 condition
1 sponsor
0 locations
NCT05557708
A Safety Study of 212Pb-Pentixather Radioligand Therapy
EARLY_PHASE1
Not yet recruiting
20 participants
Started: Jul 1, 2026 · Completed: Jun 30, 2030
3 conditions
4 sponsors
1 location
NCT04861077
Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI)
EARLY_PHASE1
Not yet recruiting
20 participants
Started: Jun 30, 2026 · Completed: Aug 31, 2028
1 condition
1 sponsor
1 location
NCT06744816
Exploring the Benefit of Topical Capsaicin in Treating Pain From Chemo-induced Peripheral Neuropathy: a Longitudinal Single Center Pilot Study
EARLY_PHASE1
Not yet recruiting
20 participants
Started: Jun 5, 2026 · Completed: Nov 30, 2027
1 condition
2 sponsors
1 location
NCT05880355
Multimodality Cardiovascular Imaging for the Translation of Therapies for Vascular Activation After MI
EARLY_PHASE1
Not yet recruiting
60 participants
Started: Apr 1, 2026 · Completed: Jan 30, 2029
1 condition
1 sponsor
1 location
NCT06346431
Efficacy of Digital Problem Solving Application in Reduction of Anxiety, Depression and Substance Use Disorder Symptoms
EARLY_PHASE1
Not yet recruiting
100 participants
Started: Mar 31, 2026 · Completed: Dec 31, 2026
3 conditions
1 sponsor
0 locations
NCT06992154
Role of Akkermansia Muciniphila in Acne Vulgaris
EARLY_PHASE1
Not yet recruiting
34 participants
Started: Mar 31, 2026 · Completed: Jan 31, 2027
1 condition
2 sponsors
0 locations
NCT06081153
Mechanistic Clinical Trial of PCSK9 Inhibition for AAA
EARLY_PHASE1
Not yet recruiting
44 participants
Started: Feb 1, 2026 · Completed: Jan 31, 2028
1 condition
3 sponsors
0 locations
NCT07128355
Botensilimab, Balstilimab, and SBRT in Colorectal Cancer
EARLY_PHASE1
Not yet recruiting
15 participants
Started: Jan 31, 2026 · Completed: Sep 30, 2027
1 condition
2 sponsors
1 location
NCT04016818
Pilot Breast-Dedicated PET Camera With 1 Millimeter Spatial Resolution
EARLY_PHASE1
Not yet recruiting
20 participants
Started: Jan 31, 2026 · Completed: Dec 31, 2026
1 condition
1 sponsor
1 location
NCT07219186
Kava Aging and Mobility Study
EARLY_PHASE1
Not yet recruiting
40 participants
Started: Jan 31, 2026 · Completed: Jan 31, 2028
7 conditions
2 sponsors
2 locations
NCT06703333
Extracorporeal Photopheresis (ECP) in the Treatment of Stiff Person Syndrome (OPTION Study)
EARLY_PHASE1
Not yet recruiting
3 participants
Started: Jan 31, 2026 · Completed: Jul 31, 2027
1 condition
1 sponsor
1 location
NCT06934915
Prednisone in Adults With an Immune-Mediated Subtype of Autism Spectrum Disorder
EARLY_PHASE1
Not yet recruiting
32 participants
Started: Jan 31, 2026 · Completed: Jan 31, 2029
1 condition
1 sponsor
1 location
NCT06999213
Lower Limb ExoNET: Development and Evaluation for Gait Assistance With Stroke Survivors
EARLY_PHASE1
Not yet recruiting
20 participants
Started: Jan 31, 2026 · Completed: Dec 31, 2029
1 condition
1 sponsor
0 locations
NCT07009522
Hamburg Emotion Awareness and Regulation Group Training for Autistic Adolescents (HEART)
EARLY_PHASE1
Not yet recruiting
21 participants
Started: Jan 15, 2026 · Completed: Feb 15, 2027
1 condition
1 sponsor
0 locations
NCT06626854
Treating Chronic Knee Pain with Noninvasive Peripheral Nerve Stimulation Using Novel Interferential RadioFrequencies
EARLY_PHASE1
Not yet recruiting
5 participants
Started: Jan 10, 2026 · Completed: Oct 10, 2026
3 conditions
1 sponsor
0 locations
NCT07208318
Restructuring the Alpha-Gamma Code in Aging Vision
EARLY_PHASE1
Not yet recruiting
240 participants
Started: Jan 10, 2026 · Completed: Aug 31, 2030
3 conditions
1 sponsor
0 locations
NCT07220122
Impact of Exogenous Ketones on Breathing in Healthy Volunteers
EARLY_PHASE1
Not yet recruiting
20 participants
Started: Jan 10, 2026 · Completed: Feb 10, 2027
1 condition
1 sponsor
1 location
NCT07214974
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
EARLY_PHASE1
Not yet recruiting
600 participants
Started: Jan 3, 2026 · Completed: Jan 3, 2030
10 conditions
1 sponsor
1 location
NCT07211399
Transition From Acute to Chronic Opioid Use and Chronic Pain
EARLY_PHASE1
Not yet recruiting
700 participants
Started: Jan 1, 2026 · Completed: Dec 1, 2030
1 condition
1 sponsor
1 location
NCT06854380
Effect of Intralesional Injection of Corticosteroids Combined with Hyaluronidase in Treatment of Minimal Associated Pathological Lesions of Vocal Folds, Participants and Condition: Patients with Benign Vocal Fold Lesions, Intervention: Intralesional Injection Via Working Channel of Nasofiberscope
EARLY_PHASE1
Recruiting
20 participants
Started: Jan 1, 2026 · Completed: Oct 1, 2026
1 condition
1 sponsor
1 location
NCT07213882
A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL)
EARLY_PHASE1
Not yet recruiting
30 participants
Started: Jan 1, 2026 · Completed: Aug 1, 2028
3 conditions
2 sponsors
0 locations
NCT07210632
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
EARLY_PHASE1
Not yet recruiting
38 participants
Started: Jan 1, 2026 · Completed: Jan 1, 2031
7 conditions
2 sponsors
1 location
NCT06102434
Safety Profile of Psilocybin for Cocaine Use Disorder
EARLY_PHASE1
Not yet recruiting
10 participants
Started: Dec 31, 2025 · Completed: Jun 30, 2026
1 condition
1 sponsor
1 location
NCT07168291
Novel Bispecific AbTCR (Anti-CD19/CD22)-T Cells in Relapsed or Refractory B-cell Lymphoma
EARLY_PHASE1
Not yet recruiting
3 participants
Started: Dec 31, 2025 · Completed: Dec 31, 2028
3 conditions
2 sponsors
1 location
NCT05183048
Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma
EARLY_PHASE1
Recruiting
14 participants
Started: Dec 31, 2025 · Completed: Mar 31, 2026
1 condition
1 sponsor
1 location
NCT07076862
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
EARLY_PHASE1
Not yet recruiting
51 participants
Started: Dec 31, 2025 · Completed: Dec 31, 2029
1 condition
3 sponsors
2 locations
NCT07065552
Tirzepatide in Obesity-Driven Endometrial Cancer
EARLY_PHASE1
Not yet recruiting
20 participants
Started: Dec 31, 2025 · Completed: Jul 31, 2028
2 conditions
1 sponsor
1 location
NCT06369350
Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion
EARLY_PHASE1
Not yet recruiting
30 participants
Started: Dec 31, 2025 · Completed: Sep 30, 2027
2 conditions
2 sponsors
0 locations
NCT05676489
MeFAMP for Imaging System a Amino Acid Transport in Primary and Metastatic Brain Tumors
EARLY_PHASE1
Not yet recruiting
28 participants
Started: Dec 30, 2025 · Completed: Aug 30, 2027
3 conditions
1 sponsor
1 location
NCT07157891
Investigating the Safety and Regenerative Potential of MSC-Derived Secretome Combined With PRGF in Knee Osteoarthritis
EARLY_PHASE1
Not yet recruiting
25 participants
Started: Dec 10, 2025 · Completed: Dec 11, 2028
3 conditions
2 sponsors
0 locations
NCT07099131
Effective Interventions to Overcome Severe Gag Reflex
EARLY_PHASE1
Not yet recruiting
45 participants
Started: Dec 7, 2025 · Completed: Dec 7, 2028
1 condition
1 sponsor
1 location
NCT04855526
THC + CBD and Memory Study
EARLY_PHASE1
Not yet recruiting
9 participants
Started: Dec 1, 2025 · Completed: Dec 30, 2026
3 conditions
2 sponsors
0 locations
NCT07183345
Application of Dynamic Pain Assessment and Management System in Perioperative Period of Patients With Incarcerated Mixed Hemorrhoids
EARLY_PHASE1
Not yet recruiting
64 participants
Started: Dec 1, 2025 · Completed: Sep 1, 2026
1 condition
1 sponsor
1 location
NCT06645769
Na-Phenylbutyrate VAscular Trial
EARLY_PHASE1
Not yet recruiting
30 participants
Started: Dec 1, 2025 · Completed: Jan 1, 2028
1 condition
2 sponsors
0 locations
NCT07039760
Asciminib With or Without Sildenafil for Brain Tumors
EARLY_PHASE1
Not yet recruiting
12 participants
Started: Dec 1, 2025 · Completed: Jun 1, 2027
1 condition
1 sponsor
1 location
NCT06062628
Ketamine in Severe Traumatic Brain Injury
EARLY_PHASE1
Recruiting
10 participants
Started: Dec 1, 2025 · Completed: Nov 30, 2026
2 conditions
1 sponsor
2 locations
NCT07038278
5-AminoLevulinic Acid Aided Resection Margins in Sarcoma
EARLY_PHASE1
Not yet recruiting
20 participants
Started: Dec 1, 2025 · Completed: Jul 1, 2028
1 condition
2 sponsors
1 location
NCT07033689
Feasibility Study of Suizenji, in Patients With Unresectable Pancreatic Ductal Adenocarcinoma (SUNRISE-II)
EARLY_PHASE1
Not yet recruiting
10 participants
Started: Dec 1, 2025 · Completed: Mar 1, 2027
1 condition
1 sponsor
1 location
NCT05326633
Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
EARLY_PHASE1
Not yet recruiting
78 participants
Started: Dec 1, 2025 · Completed: May 30, 2027
3 conditions
1 sponsor
1 location
NCT07198815
A Preliminary Exploratory Clinical Trial to Evaluate the Efficacy of NPDR-01 Eye Drops in the Treatment of Non-Proliferative Diabetic Retinopathy
EARLY_PHASE1
Not yet recruiting
10 participants
Started: Dec 1, 2025 · Completed: Dec 1, 2026
4 conditions
1 sponsor
0 locations
NCT07050836
Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation
EARLY_PHASE1
Not yet recruiting
100 participants
Started: Dec 1, 2025 · Completed: Jun 30, 2027
2 conditions
1 sponsor
1 location
NCT06884748
Prevention of Recurrence of Clostridioides Difficile Colitis With Ursodeoxycholic Acid (UCDA) as a Supplement to Standard Therapy
EARLY_PHASE1
Not yet recruiting
30 participants
Started: Dec 1, 2025 · Completed: May 1, 2028
1 condition
1 sponsor
1 location
NCT07055529
Comparison of Efficacy and Safety Psoralen Combined With Ultraviolet A (PUVA) Vs Tofacitinib in the Treatment of Generalized Vitiligo.
EARLY_PHASE1
Not yet recruiting
64 participants
Started: Dec 1, 2025 · Completed: May 31, 2026
1 condition
1 sponsor
1 location
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