Baminercept, a Lymphotoxin-Beta Receptor Fusion Protein, for Treatment of Sjögren's Syndrome

PHASE2TerminatedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

January 31, 2015

Study Completion Date

June 30, 2015

Conditions
Primary Sjögren's Syndrome
Interventions
BIOLOGICAL

Baminercept

Subjects randomized to baminercept (2:1) will receive 24 weekly injections of 100 mg administered subcutaneously starting at the Day 0 visit and ending at Week 23.

OTHER

Placebo

Subjects randomized to placebo will receive 24 weekly injections of 100 mg administered subcutaneously starting at the Day 0 visit and ending at Week 23.

Trial Locations (9)

14642

University of Rochester Medical Center, Rochester

15260

University of Pittsburgh, Pittsburgh

21224

Johns Hopkins Medical Institute, Baltimore

27710

Duke University Medical Center, Durham

60637

University of Chicago, Chicago

73104

Oklahoma Medical Research Foundation, Oklahoma City

90048

Cedars-Sinai Medical Center, Los Angeles

94304

Stanford University, Palo Alto

06105

St. Francis Hospital and Medical Center, Hartford

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Autoimmunity Centers of Excellence

OTHER

collaborator

Biogen

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT01552681 - Baminercept, a Lymphotoxin-Beta Receptor Fusion Protein, for Treatment of Sjögren's Syndrome | Biotech Hunter | Biotech Hunter