Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

November 27, 2023

Primary Completion Date

May 31, 2026

Study Completion Date

March 31, 2027

Conditions
Spinal Muscular AtrophySpine DeformityScoliosis
Interventions
DEVICE

ThecaFlex DRx System

The ThecaFlex DRx™ System consists of an implantable intrathecal catheter, and an implantable subcutaneous port, designed specifically to meet the implantation, Cerebrospinal Fluid (CSF) aspiration, and intrathecal delivery and dosing needs of patients (aged ≥ 3 years) requiring repeated/on-going intermittent chronic bolus intrathecal treatment for life threatening, debilitating Central Nervous System (CNS) disorders who are precluded from Lumbar Puncture (LP) due to complex spine conditions, or who are resistant to LP for therapy administration or CSF aspiration.

Trial Locations (20)

10032

NOT_YET_RECRUITING

Columbia University Irving Medical Center/NewYork Presbyterian Hospital, New York

17033

RECRUITING

Penn State Milton S. Hershey Medical Center, Hershey

19104

RECRUITING

Children's Hospital Philadelphia, Philadelphia

20162

RECRUITING

Centro Clinico Nemo, Milan

22903

RECRUITING

University of Virginia, Charlottesville

23510

RECRUITING

Childrens Hospital of the King's Daughters, Norfolk

44106

RECRUITING

UH Rainbow Babies and Children's Hospital, Cleveland

46026

RECRUITING

Hospital Universitario y Politecnico la Fe de Valencia, Valencia

49503

RECRUITING

Helen DeVos Children's Hospital, Grand Rapids

60611

RECRUITING

Lurie Childrens Hospital, Chicago

77030

RECRUITING

Texas Children's Hospital, Houston

85013

RECRUITING

Barrow Neurological Institute, Phoenix

92037

RECRUITING

Rady Children's Hospital, San Diego

92868

RECRUITING

Children's Hospital Orange County, Orange

94301

RECRUITING

Stanford Medical Center, Palo Alto

02115

RECRUITING

Boston Children's Hospital, Boston

Unknown

RECRUITING

Universitätsklinikum Essen, Essen

RECRUITING

Specialised Hospital Ludwika Rydygiera, Krakow

RECRUITING

Research Institute of Polish Mother's Memorial Hospital, Lodz

RECRUITING

Hospital Universitario La Paz, Madrid

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Biogen

INDUSTRY

lead

Alcyone Therapeutics, Inc

INDUSTRY