A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder

PHASE3CompletedINTERVENTIONAL
Enrollment

440

Participants

Timeline

Start Date

November 9, 2020

Primary Completion Date

October 25, 2021

Study Completion Date

December 22, 2021

Conditions
Depressive Disorder, Major
Interventions
DRUG

SAGE-217

Oral capsules

DRUG

Matching Placebo

Oral capsules

DRUG

Sertraline

Oral tablets

DRUG

Escitalopram

Oral tablets

DRUG

Citalopram

Oral tablets

DRUG

Duloxetine

Oral capsules

DRUG

Desvenlafaxine

Oral tablets

Trial Locations (51)

10549

Sage Investigational Site, Mount Kisco

11229

Sage Investigational Site, Brooklyn

11235

Sage Investigational Site, Brooklyn

19462

Sage Investigational Site, Plymouth Meeting

21204

Sage Investigational Site, Towson

30022

Sage Investigational Site, Alpharetta

30060

Sage Investigational Site, Marietta

30331

Sage Investigational Site, Atlanta

31405

Sage Investigational Site, Savannah

32256

Sage Investigational Site, Jacksonville

32502

Sage Investigational Site, Pensacola

32801

Sage Investigational Site, Orlando

32807

Sage Investigational Site, Orlando

33067

Sage Investigational Site, Coral Springs

36303

Sage Investigational Site, Dothan

44122

Sage Investigational Site, Beachwood

44720

Sage Investigational Site, North Canton

45212

Sage Investigational Site, Cincinnati

45215

Sage Investigational Site, Cincinnati

45219

Sage Investigational Site, Cincinnati

48109

Sage Investigational Site, Ann Arbor

60634

Sage Investigational Site, Chicago

60640

Sage Investigational Site, Chicago

63304

Sage Investigational Site, Saint Charles

68526

Sage Investigational Site, Lincoln

73112

Sage Investigational Site, Oklahoma City

75231

Sage Investigational Site, Dallas

76309

Sage Investigational Site, Wichita Falls

77030

Sage Investigational Site, Houston

77081

Sage Investigational Site, Houston

78759

Sage Investigational Site, Austin

80910

Sage Investigational Site, Colorado Springs

85012

Sage Investigational Site, Phoenix

87109

Sage Investigational Site, Albuquerque

90720

Sage Investigational Site, Los Alamitos

91206

Sage Investigational Site, Glendale

92056

Sage Investigational Site, Oceanside

92103

Sage Investigational Site, San Diego

92503

Sage Investigational Site, Riverside

92591

Sage Investigational Site, Temecula

92614

Sage Investigational Site, Irvine

92626

Sage Investigational Site, Costa Mesa

92805

Sage Investigational Site, Anaheim

92868

Sage Investigational Site, Orange

98007

Sage Investigational Site, Bellevue

06416

Sage Investigational Site, Cromwell

06360

Sage Investigational Site, Norwich

02472

Sage Investigational Site, Watertown

08002

Sage Investigational Site, Cherry Hill

08053

Sage Investigational Site, Marlton

08540

Sage Investigational Site, Princeton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Biogen

INDUSTRY

NCT04476030 - A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder | Biotech Hunter | Biotech Hunter