A Study of Avonex to Determine the Effects of Dose Titration on the Incidence of Flu Like Symptoms in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

May 5, 2010

Primary Completion Date

October 23, 2010

Study Completion Date

October 23, 2010

Conditions
Healthy Volunteers
Interventions
DRUG

Avonex

Group 1 subjects will receive weekly Avonex 30 mcg (full dose) IM injections from Week 1 to Week 8. Group 2 subjects will titrate in quarter dose increments every week up to a full dose of Avonex over a 3 week period from Week 1 to Week 3 and then continue on full dose from Week 4 to Week 8. Group 3 subjects will titrate in quarter dose increments every 2 weeks up to a full dose of Avonex over a 6 week period from Week 1 to Week 6 and continue on full dose from Week 7 to Week 8

Trial Locations (1)

Unknown

Research Site, Saint Paul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Biogen

INDUSTRY