Agios Pharmaceuticals

NCT01114750

A Study to Determine the Absorption of Peroral Insulin in Dextran Matrix (ORA3)

NCT02108106

A Phase I Study of AG-348 in Healthy Volunteers

NCT02149966

A Phase I Study of AG-348 in Healthy Volunteers

NCT02218346

Food Effect Study of AG-221 in Healthy Male Subjects

NCT02489513

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-AG-120

NCT02492737

Study of Orally Administered AG-881 in Patients With Advanced Hematologic Malignancies With an IDH1 and/or IDH2 Mutation

NCT02579707

Food Effect Study of AG120 in Healthy Subjects

NCT02630927

A Safety and Tolerability Study of AG-519 in Healthy Subjects

NCT02831972

Drug-Drug Interaction Study of AG120 in Healthy Subjects

NCT03071770

Japanese Bridging Study of Ivosidenib (AG-120) in Healthy Subjects

NCT03250598

Study to Evaluate the Pharmacokinetics, Safety, and QTc Effect of AG-348 in Healthy Subjects of Japanese Origin and Non-Asian Origin

NCT03282513

A Study of AG-120 (Ivosidenib) in Subjects With Mild or Moderate Hepatic Impairment or Normal Hepatic Function

NCT03397329

Study to Evaluate the Relative Bioavailability and Safety of the AG-348 Tablet and Capsule Formulations in Healthy Adults

NCT03703505

A Study to Evaluate the Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability of AG-348 in Healthy Male Participants Following Administration of a Single Oral Dose of [14C]AG-348 and Concomitant Single Intravenous Microdose of [13C6]AG-348

NCT03564821

IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation

NCT03960502

A Safety and Pharmacokinetic Study of AG-881 in Healthy Male Participants Following Administration of a Single Oral Dose of [14C] AG-881 and Concomitant Intravenous Microdose of [13C315N3] AG-881

NCT03834584

A Study of AG-636 in the Treatment of Subjects With Advanced Lymphoma

NCT03991312

Study to Evaluate the Effect of Multiple Doses of Itraconazole and Rifampin on the Single-Dose Pharmacokinetics of Mitapivat Sulfate (AG-348) in Healthy Adult Participants

NCT04015687

A Study to Evaluate the Effect of AG-881 on the Pharmacokinetics of a Single Dose of Lamotrigine in Healthy Adults

NCT04128787

A Study to Compare the Relative Bioavailability of Two AG-881 Formulations and Evaluate the Effect of Food and Omeprazole on the Pharmacokinetics of AG-881

NCT04145128

A Study to Evaluate AG-881 in Healthy Japanese and Non-Asian Participants

NCT04472832

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Mitapivat (AG-348) in Healthy Adult Participants

NCT04536792

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease

NCT04565678

A Study to Assess the Relative Bioavailability and Effect of Food on the Coated Granule Formulation of Mitapivat in Healthy Participants

NCT04696393

A Study to Compare the Pharmacokinetics and Safety of Mitapivat 100 mg Tablet Formulation With Mitapivat 2 × 50 mg Tablet Formulation in Healthy Adult Participants

NCT05610657

A Pharmacokinetic Study of Mitapivat in Participants With Moderate Hepatic Impairment Compared to Matched Healthy Control Participants With Normal Hepatic Function

NCT06286033

Single and Multiple Ascending Dose Study and Food Effect Study for AG181

NCT06648824

Study of How Mitapivat Affects Midazolam Blood Levels in Healthy Participants

NCT06745271

A Study to Determine How Tebapivat is Absorbed, Broken Down, and Removed From the Body and the Extent to Which Tebapivat is Made Available in the Body in Healthy Participants

NCT07075640

A Study to Determine the Safety and Tolerability of AG-236 and How it is Absorbed, Broken Down, and Eliminated From the Body in Healthy Participants