Study of Orally Administered AG-881 in Patients With Advanced Hematologic Malignancies With an IDH1 and/or IDH2 Mutation

PHASE1CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

August 7, 2015

Primary Completion Date

March 21, 2018

Study Completion Date

March 21, 2018

Conditions
Acute Myeloid Leukemia (AML)Myelodysplastic SyndromeHematologic Malignancies
Interventions
DRUG

AG881

AG-881 administered continuously as a single agent dosed orally on Days 1 to 28 of a 28-day cycle. Patients may continue treatment with AG-881 until disease progression or development of other unacceptable toxicity

Trial Locations (6)

10065

New York

60611

Chicago

77030

Houston

80045

Aurora

94800

Villejuif

02215

Boston

Sponsors
All Listed Sponsors
lead

Agios Pharmaceuticals, Inc.

INDUSTRY