NCT03991312View on ClinicalTrials.gov

Study to Evaluate the Effect of Multiple Doses of Itraconazole and Rifampin on the Single-Dose Pharmacokinetics of Mitapivat Sulfate (AG-348) in Healthy Adult Participants

PHASE1CompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

June 20, 2019

Primary Completion Date

August 14, 2019

Study Completion Date

September 10, 2019

Conditions
Healthy Volunteers
Interventions
DRUG

itraconazole

Participants will receive an oral solution as described in the arm description.

DRUG

rifampin

Participants will receive oral capsule(s) as described in the arm description.

DRUG

mitapivat sulfate

Participants will receive an oral tablet as described in the arm description.

Trial Locations (1)

85283

Celerion, Inc, Tempe

Sponsors
All Listed Sponsors
lead

Agios Pharmaceuticals, Inc.

INDUSTRY