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Clinical Trials for Chugai Pharma
Explore 33 clinical trials worldwide
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Showing 1-33 of 33 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Chugai Pharma
Clinical Trials (33)
NCT06793215
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
PHASE3
Recruiting
600 participants
Started: Dec 1, 2025 · Completed: Oct 31, 2030
2 conditions
2 sponsors
10 locations
NCT07107490
A PHASE I STUDY OF ALPS12 IN PATIENTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER
PHASE1
Not yet recruiting
122 participants
Started: Sep 1, 2025 · Completed: Sep 30, 2028
1 condition
1 sponsor
1 location
NCT07030959
Study of AUBE00 in Patients With Solid Tumors
PHASE1
Recruiting
100 participants
Started: Jun 5, 2025 · Completed: Jun 30, 2030
1 condition
1 sponsor
4 locations
NCT06819891
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
PHASE3
Recruiting
425 participants
Started: May 12, 2025 · Completed: Dec 31, 2028
1 condition
2 sponsors
112 locations
NCT06819878
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
PHASE3
Recruiting
600 participants
Started: Mar 17, 2025 · Completed: Dec 31, 2033
1 condition
2 sponsors
249 locations
NCT06723106
Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)
PHASE1
Enrolling by invitation
144 participants
Started: Dec 9, 2024 · Completed: Apr 30, 2027
6 conditions
1 sponsor
54 locations
NCT06497556
A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer
PHASE3
Recruiting
320 participants
Started: Sep 23, 2024 · Completed: Nov 30, 2029
2 conditions
2 sponsors
253 locations
NCT06589986
A Study to Assess the Efficacy and Safety of Afimkibart (Also Known as RO7790121) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis
PHASE3
Recruiting
400 participants
Started: Sep 17, 2024 · Completed: Dec 30, 2029
1 condition
2 sponsors
307 locations
NCT06793553
Induction Therapy of PTX+BV Followed by Atezolizumab+Nab-PTX for PD-L1+ TNBC
PHASE2
Recruiting
106 participants
Started: Sep 13, 2024 · Completed: Sep 30, 2028
1 condition
2 sponsors
1 location
NCT06371417
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
PHASE1
Recruiting
144 participants
Started: Aug 19, 2024 · Completed: Jun 30, 2026
6 conditions
1 sponsor
67 locations
NCT05867121
A Study to Evaluate Safety, Pharmacokinetics, & Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors; Urothelial Carcinoma Substudy in Association With RO7496353 Study GO44010
PHASE1
Active, not recruiting
102 participants
Started: Oct 2, 2023 · Completed: Jun 30, 2026
3 conditions
2 sponsors
29 locations
NCT05902078
Eldecalcitol and Calcitriol in Postmenopausal Women With Low Bone Mineral Density or Mild Osteoporosis
PHASE4
Recruiting
300 participants
Started: Sep 27, 2023 · Completed: Dec 31, 2025
2 conditions
2 sponsors
21 locations
NCT05904886
A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) (IMbrave152)
PHASE3
Active, not recruiting
687 participants
Started: Sep 14, 2023 · Completed: Sep 1, 2026
1 condition
2 sponsors
172 locations
NCT05884372
Comparison of Efficacy of Denosumab With Eldecalcitol or Native Vitamin D in Postmenopausal Women With Osteoporosis.
PHASE4
Recruiting
100 participants
Started: Aug 24, 2023 · Completed: Jun 30, 2025
1 condition
2 sponsors
1 location
NCT05907980
A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors
PHASE1
Recruiting
219 participants
Started: May 24, 2023 · Completed: Dec 31, 2026
1 condition
1 sponsor
4 locations
NCT05802836
Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab
N/A
Recruiting
100 participants
Started: Apr 26, 2023 · Completed: Dec 31, 2029
3 conditions
3 sponsors
1 location
NCT05735366
A Phase 1 Study of SAIL66 in Patients With CLDN6-positive Locally Advanced or Metastatic Solid Tumors
PHASE1
Active, not recruiting
231 participants
Started: Apr 18, 2023 · Completed: Oct 31, 2029
1 condition
1 sponsor
9 locations
NCT05503264
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) Encephalitis
PHASE3
Recruiting
152 participants
Started: Sep 27, 2022 · Completed: Dec 14, 2029
2 conditions
2 sponsors
87 locations
NCT05271409
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
PHASE3
Recruiting
152 participants
Started: Aug 30, 2022 · Completed: Dec 31, 2028
1 condition
2 sponsors
82 locations
NCT05679570
Satralizumab in the Treatment of Pulmonary Arterial Hypertension (SATISFY-JP Trial)
PHASE2
Active, not recruiting
20 participants
Started: Jul 12, 2022 · Completed: Jun 30, 2026
1 condition
4 sponsors
9 locations
NCT04958265
A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
PHASE3
Active, not recruiting
41 participants
Started: Nov 17, 2021 · Completed: May 19, 2029
1 condition
2 sponsors
22 locations
NCT04861259
A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
PHASE3
Active, not recruiting
83 participants
Started: Oct 22, 2021 · Completed: Aug 20, 2029
1 condition
2 sponsors
45 locations
NCT05012618
A Dose-escalation Study of LUNA18 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).
PHASE1
Active, not recruiting
195 participants
Started: Oct 8, 2021 · Completed: Aug 31, 2026
1 condition
1 sponsor
20 locations
NCT04928677
A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment
PHASE1
Recruiting
50 participants
Started: Jun 9, 2021 · Completed: Jun 30, 2026
2 conditions
2 sponsors
5 locations
NCT05022927
A Phase I Study of ERY974 in Patients With Hepatocellular Carcinoma
PHASE1
Active, not recruiting
179 participants
Started: Jun 1, 2021 · Completed: Dec 31, 2025
1 condition
1 sponsor
11 locations
NCT04732598
A Phase III Study of Bevacizumab and Paclitaxel in Combination with Atezolizumab As a Treatment for Locally Advanced Unresectable or Metastatic Hormone Receptor-positive HER2 Negative Breast Cancer
PHASE3
Active, not recruiting
280 participants
Started: Jan 21, 2021 · Completed: Sep 30, 2025
1 condition
2 sponsors
1 location
NCT04434092
A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors
PHASE3
Active, not recruiting
204 participants
Started: Oct 8, 2020 · Completed: Sep 30, 2027
1 condition
2 sponsors
56 locations
NCT04432584
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors
PHASE3
Active, not recruiting
190 participants
Started: Sep 30, 2020 · Completed: Sep 30, 2027
1 condition
2 sponsors
69 locations
NCT04511845
A Dose-Escalation Study of SPYK04 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).
PHASE1
Active, not recruiting
113 participants
Started: Sep 10, 2020 · Completed: Sep 30, 2026
1 condition
1 sponsor
15 locations
NCT03805022
Benefit of Intensified Peri-operative Chemotherapy Within High-risk CINSARC Patients With Resectable Soft-tissue Sarcomas
PHASE3
Recruiting
351 participants
Started: Feb 14, 2019 · Completed: Dec 31, 2028
2 conditions
3 sponsors
10 locations
NCT03157635
Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria
PHASE1/PHASE2
Active, not recruiting
59 participants
Started: Nov 14, 2016 · Completed: Jan 31, 2026
1 condition
2 sponsors
14 locations
NCT02407509
Phase I Trial of VS-6766 Alone and in Combination With Everolimus
PHASE1
Active, not recruiting
104 participants
Started: Jun 17, 2013 · Completed: Sep 30, 2025
4 conditions
4 sponsors
3 locations
NCT00470223
Combined Chemotherapy With or Without Zoledronic Acid for Patients With Osteosarcoma
PHASE3
Active, not recruiting
318 participants
Started: Mar 31, 2007 · Completed: Dec 31, 2026
1 condition
6 sponsors
37 locations