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Clinical Trials for Genmab
Explore 51 clinical trials worldwide
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Showing 1-50 of 51 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Genmab
Clinical Trials (51)
NCT06919939
Epcoritamab in Combination With Loncastuximab Tesirine in Relapsed/Refractory Large B-cell Lymphoma
PHASE2
Not yet recruiting
26 participants
Started: Dec 1, 2025 · Completed: Dec 1, 2030
2 conditions
3 sponsors
1 location
NCT07166094
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
PHASE3
Not yet recruiting
544 participants
Started: Oct 15, 2025 · Completed: Feb 28, 2029
2 conditions
1 sponsor
0 locations
NCT06796998
Epcoritamab in Patients With Newly Diagnosed Marginal Zone Lymphoma (MZL)
PHASE2
Recruiting
25 participants
Started: Oct 1, 2025 · Completed: Apr 30, 2030
4 conditions
3 sponsors
1 location
NCT07030699
A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma
PHASE2
Recruiting
27 participants
Started: Aug 13, 2025 · Completed: Aug 31, 2028
1 condition
3 sponsors
7 locations
NCT07108998
Study of Epcoritamab as a Consolidation Therapy in CLL/SLL
PHASE2
Not yet recruiting
22 participants
Started: Aug 1, 2025 · Completed: Jul 1, 2029
7 conditions
2 sponsors
1 location
NCT06984328
Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07)
PHASE2
Recruiting
90 participants
Started: Jul 25, 2025 · Completed: Jul 15, 2029
3 conditions
1 sponsor
2 locations
NCT07079631
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
PHASE1/PHASE2
Recruiting
482 participants
Started: Jul 18, 2025 · Completed: May 31, 2031
1 condition
2 sponsors
1 location
NCT06672705
Epcoritamab for the Treatment of Relapsed or Refractory Post Transplant Lymphoproliferative Disorders
PHASE1
Recruiting
26 participants
Started: Jun 16, 2025 · Completed: Dec 31, 2026
6 conditions
3 sponsors
2 locations
NCT06811272
Outpatient Epcoritamab as 2L in NTE R/R DLBCL
PHASE2
Recruiting
30 participants
Started: Jun 5, 2025 · Completed: Oct 1, 2028
2 conditions
2 sponsors
2 locations
NCT06952660
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
PHASE4
Recruiting
100 participants
Started: May 7, 2025 · Completed: Dec 13, 2028
1 condition
2 sponsors
25 locations
NCT06536049
Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma
PHASE1/PHASE2
Recruiting
38 participants
Started: Apr 2, 2025 · Completed: Dec 31, 2028
14 conditions
3 sponsors
2 locations
NCT06830759
Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma
N/A
Recruiting
700 participants
Started: Mar 28, 2025 · Completed: Sep 30, 2031
2 conditions
2 sponsors
39 locations
NCT06619236
Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer
PHASE3
Recruiting
530 participants
Started: Feb 7, 2025 · Completed: May 23, 2028
1 condition
1 sponsor
83 locations
NCT06563596
Epco, Zanu, Ritux for R/R FL or MZL
PHASE2
Recruiting
45 participants
Started: Jan 21, 2025 · Completed: Mar 1, 2030
6 conditions
3 sponsors
2 locations
NCT06447376
Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab
PHASE1
Recruiting
20 participants
Started: Jan 14, 2025 · Completed: Sep 1, 2028
2 conditions
4 sponsors
1 location
NCT06510491
Epcoritamab in Previously Treated WM
PHASE2
Recruiting
20 participants
Started: Dec 6, 2024 · Completed: Dec 31, 2027
2 conditions
2 sponsors
3 locations
NCT06635824
Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)
PHASE3
Recruiting
702 participants
Started: Nov 25, 2024 · Completed: Oct 31, 2029
1 condition
1 sponsor
221 locations
NCT06510361
Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy
PHASE2
Recruiting
35 participants
Started: Nov 20, 2024 · Completed: May 1, 2028
4 conditions
2 sponsors
1 location
NCT06685068
A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors
PHASE1/PHASE2
Recruiting
260 participants
Started: Nov 13, 2024 · Completed: Jun 29, 2028
1 condition
1 sponsor
4 locations
NCT06458439
Epcoritamab-CAR T Cells for Large B-cell Lymphomas
PHASE2
Recruiting
31 participants
Started: Sep 24, 2024 · Completed: Dec 31, 2027
5 conditions
2 sponsors
1 location
NCT06573294
Trial to Assess the Safety and Antitumor Activity of GEN1057 in Malignant Solid Tumors
PHASE1
Recruiting
45 participants
Started: Aug 28, 2024 · Completed: Jan 31, 2026
2 conditions
1 sponsor
5 locations
NCT06508658
A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to Intravenously (IV) Infused Rituximab Plus IV Infused Gemcitabine and IV Infused Oxaliplatin in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
PHASE3
Recruiting
360 participants
Started: Aug 13, 2024 · Completed: Jan 31, 2028
1 condition
2 sponsors
164 locations
NCT06391775
Trial to Assess the Safety and Preliminary Efficacy of GEN1055 on Malignant Solid Tumors as Monotherapy and as Combination Therapy
PHASE1/PHASE2
Active, not recruiting
21 participants
Started: May 14, 2024 · Completed: May 31, 2028
1 condition
2 sponsors
4 locations
NCT06191744
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
PHASE3
Recruiting
1,095 participants
Started: Feb 5, 2024 · Completed: Nov 30, 2037
1 condition
2 sponsors
249 locations
NCT06150183
Safety and Preliminary Efficacy of BNT314 in Cancer Patients With Malignant Solid Tumors
PHASE1
Active, not recruiting
41 participants
Started: Nov 30, 2023 · Completed: Sep 30, 2026
1 condition
2 sponsors
14 locations
NCT06057038
A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors
PHASE1
Active, not recruiting
42 participants
Started: Nov 24, 2023 · Completed: Dec 26, 2026
1 condition
2 sponsors
3 locations
NCT05852717
Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma
PHASE2
Recruiting
32 participants
Started: Oct 31, 2023 · Completed: Nov 30, 2028
3 conditions
2 sponsors
4 locations
NCT05848765
Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapy
PHASE2
Recruiting
284 participants
Started: Sep 4, 2023 · Completed: Nov 30, 2031
2 conditions
3 sponsors
25 locations
NCT05783609
Epcoritamab and Rituximab for First-line Follicular Lymphoma
PHASE2
Recruiting
100 participants
Started: Jun 21, 2023 · Completed: Feb 28, 2030
2 conditions
3 sponsors
4 locations
NCT05721222
Trial of PRO1160 (GEN1160) in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) (PRO1160-001)
PHASE1/PHASE2
Recruiting
110 participants
Started: Mar 15, 2023 · Completed: Dec 31, 2026
3 conditions
1 sponsor
17 locations
NCT05660967
Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma
PHASE2
Active, not recruiting
111 participants
Started: Mar 6, 2023 · Completed: Jul 31, 2027
1 condition
2 sponsors
74 locations
NCT05578976
A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)
PHASE3
Active, not recruiting
900 participants
Started: Feb 8, 2023 · Completed: Dec 31, 2029
1 condition
1 sponsor
331 locations
NCT05579366
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
PHASE1/PHASE2
Recruiting
569 participants
Started: Dec 7, 2022 · Completed: Sep 30, 2027
15 conditions
1 sponsor
38 locations
NCT05586321
Study of Safety and Antitumor Activity of GEN1056 in Participants With Advanced Solid Tumors
PHASE1
Active, not recruiting
26 participants
Started: Oct 24, 2022 · Completed: Oct 21, 2025
1 condition
2 sponsors
7 locations
NCT05206357
Study of the Adverse Events and Change in Disease State of Pediatric Participants (and Young Adults Between the Ages of 18-25) With Relapsed/Refractory Aggressive Mature B-cell Neoplasms Receiving Subcutaneous (SC) Injections of Epcoritamab
PHASE1
Active, not recruiting
17 participants
Started: Oct 4, 2022 · Completed: Nov 30, 2028
1 condition
2 sponsors
41 locations
NCT05409066
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma
PHASE3
Active, not recruiting
549 participants
Started: Sep 20, 2022 · Completed: Dec 31, 2029
1 condition
2 sponsors
273 locations
NCT05451810
A Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the Outpatient Setting in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Classic Follicular Lymphoma
PHASE2
Active, not recruiting
184 participants
Started: Aug 17, 2022 · Completed: Mar 31, 2027
2 conditions
2 sponsors
72 locations
NCT05283720
A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma
PHASE2
Recruiting
565 participants
Started: Jun 14, 2022 · Completed: Nov 30, 2032
1 condition
2 sponsors
74 locations
NCT05201248
A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Therapies in Adult Participants in China With B-Cell Non-Hodgkin Lymphoma
PHASE1/PHASE2
Active, not recruiting
49 participants
Started: Mar 10, 2022 · Completed: Apr 30, 2025
1 condition
2 sponsors
18 locations
NCT05180474
GEN1047 for Solid Tumors - First in Human (FIH) Trial
PHASE1/PHASE2
Active, not recruiting
179 participants
Started: Dec 13, 2021 · Completed: Mar 26, 2026
4 conditions
1 sponsor
36 locations
NCT05117242
Safety and Efficacy Study of GEN1046 as a Single Agent or in Combination With Pembrolizumab for Treatment of Recurrent (Non-small Cell) Lung Cancer
PHASE2
Active, not recruiting
125 participants
Started: Oct 27, 2021 · Completed: Mar 31, 2027
1 condition
2 sponsors
42 locations
NCT04697628
Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer
PHASE3
Active, not recruiting
502 participants
Started: Feb 22, 2021 · Completed: May 7, 2026
1 condition
2 sponsors
217 locations
NCT04628494
A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)
PHASE3
Active, not recruiting
556 participants
Started: Jan 13, 2021 · Completed: Apr 30, 2028
1 condition
2 sponsors
208 locations
NCT04623541
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
PHASE1/PHASE2
Recruiting
424 participants
Started: Nov 25, 2020 · Completed: Aug 31, 2029
4 conditions
3 sponsors
87 locations
NCT04663347
Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)
PHASE1/PHASE2
Active, not recruiting
543 participants
Started: Nov 3, 2020 · Completed: Sep 30, 2028
2 conditions
2 sponsors
57 locations
NCT04542824
Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL)
PHASE1/PHASE2
Active, not recruiting
78 participants
Started: Aug 20, 2020 · Completed: Sep 30, 2027
6 conditions
2 sponsors
15 locations
NCT04083599
GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
PHASE1/PHASE2
Active, not recruiting
350 participants
Started: Sep 17, 2019 · Completed: Nov 30, 2026
6 conditions
2 sponsors
76 locations
NCT03917381
GEN1046 Safety Trial in Patients With Malignant Solid Tumors
PHASE1/PHASE2
Active, not recruiting
429 participants
Started: May 14, 2019 · Completed: Feb 28, 2026
7 conditions
1 sponsor
57 locations
NCT03786081
Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer
PHASE1/PHASE2
Active, not recruiting
214 participants
Started: Feb 27, 2019 · Completed: Mar 31, 2026
1 condition
6 sponsors
71 locations
NCT03625037
First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma
PHASE1/PHASE2
Active, not recruiting
666 participants
Started: Jun 26, 2018 · Completed: Jan 31, 2029
9 conditions
2 sponsors
85 locations
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