A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Therapies in Adult Participants in China With B-Cell Non-Hodgkin Lymphoma

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

March 10, 2022

Primary Completion Date

April 30, 2025

Study Completion Date

April 30, 2025

Conditions
B-Cell Non-Hodgkin Lymphoma
Interventions
DRUG

Epcoritamab

Subcutaneous Injection (SC)

DRUG

Cyclophosphamide

IV Injection

DRUG

Rituximab

Intravenous (IV) Infusion

DRUG

Doxorubicin

IV Infusion

DRUG

Vincristine

IV Infusion

DRUG

Prednisone

Oral; Tablet

DRUG

Lenalidomide

Oral; Capsule

Trial Locations (18)

100071

The Fifth Medical Center of PLA General Hospital /ID# 230520, Beijing

100191

Peking University Third Hospital /ID# 228138, Beijing

200065

Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 227724, Shanghai

215006

The First Affiliated Hospital of Soochow University /ID# 228024, Suzhou

221006

The Affiliated Hospital of Xuzhou Medical College /ID# 228774, Xuzhou

300000

Tianjin Cancer Hospital /ID# 228135, Tianjin

310003

The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 228154, Hangzhou

310022

Zhejiang Cancer hospital /ID# 228776, Hangzhou

330006

The First Affiliated Hospital of Nanchang University /ID# 228771, Nanchang

330029

Jiangxi Provincial Cancer Hospital /ID# 231944, Nanchang

350001

Fujian Medical University Union Hospital /ID# 231890, Fuzhou

410006

Hunan Cancer Hospital /ID# 231859, Changsha

430022

Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 231221, Wuhan

450008

Henan Cancer Hospital /ID# 228772, Zhengzhou

510060

Sun Yat-Sen University Cancer Center /ID# 228033, Guangzhou

510080

Guangdong Provincial People's Hospital /ID# 228028, Guangzhou

510515

Nanfang Hospital of Southern Medical University /ID# 227916, Guangzhou

610041

West China Hospital, Sichuan University /ID# 231434, Chengdu

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

AbbVie

INDUSTRY

lead

Genmab

INDUSTRY