Epcoritamab for the Treatment of Relapsed or Refractory Post Transplant Lymphoproliferative Disorders

PHASE1RecruitingINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

June 16, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative DisorderEBV-Related Post-Transplant Lymphoproliferative DisorderRecurrent Monomorphic Post-Transplant Lymphoproliferative DisorderRecurrent Polymorphic Post-Transplant Lymphoproliferative DisorderRefractory Monomorphic Post-Transplant Lymphoproliferative DisorderRefractory Polymorphic Post-Transplant Lymphoproliferative Disorder
Interventions
PROCEDURE

Biopsy

Undergo biopsy

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Computed Tomography

Undergo PET/CT

BIOLOGICAL

Epcoritamab

Given SC

PROCEDURE

Positron Emission Tomography

Undergo PET/CT

Trial Locations (2)

43210

RECRUITING

Ohio State University Comprehensive Cancer Center, Columbus

63110

RECRUITING

Washington University, St Louis

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

AbbVie

INDUSTRY

collaborator

Genmab

INDUSTRY

lead

Timothy Voorhees

OTHER