Clinical Trials for Daiichi Sankyo

Explore 158 clinical trials worldwide

Showing 1-50 of 158 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: Daiichi Sankyo

Clinical Trials (158)

NCT07206472
A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia
N/ANot yet recruiting
2,560 participants
Started: Nov 30, 2025 · Completed: Mar 1, 2029
2 conditions1 sponsor0 locations
NCT07022483
Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
PHASE3Not yet recruiting
710 participants
Started: Oct 31, 2025 · Completed: Mar 23, 2032
1 condition2 sponsors0 locations
NCT06899126
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
PHASE3Recruiting
686 participants
Started: Oct 7, 2025 · Completed: Jul 5, 2032
1 condition2 sponsors26 locations
NCT07201545
Evaluating Bioequivalence of a Fixed Dose Combination Versus Tablets of Bempedoic Acid / Ezetimibe and Rosuvastatin
PHASE1Not yet recruiting
58 participants
Started: Oct 7, 2025 · Completed: Nov 26, 2025
1 condition1 sponsor1 location
NCT07182591
A Study of DS5361b in Participants With Advanced Solid Tumors
PHASE1Recruiting
192 participants
Started: Oct 2, 2025 · Completed: Dec 3, 2030
1 condition1 sponsor2 locations
NCT07159126
A Study of DS3610a in Participants With Advanced Solid Tumor
PHASE1Not yet recruiting
70 participants
Started: Oct 1, 2025 · Completed: Feb 1, 2031
2 conditions1 sponsor0 locations
NCT07189403
A Study of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma and Metastatic Castration-resistant Prostate Cancer
PHASE1Not yet recruiting
40 participants
Started: Oct 1, 2025 · Completed: Mar 1, 2028
2 conditions1 sponsor6 locations
NCT07205822
A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer
PHASE3Not yet recruiting
100 participants
Started: Sep 30, 2025 · Completed: Feb 2, 2028
1 condition2 sponsors37 locations
NCT07182383
Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Rosuvastatin
PHASE1Not yet recruiting
58 participants
Started: Sep 29, 2025 · Completed: Nov 18, 2025
1 condition1 sponsor1 location
NCT07129993
Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma
PHASE2/PHASE3Recruiting
630 participants
Started: Sep 26, 2025 · Completed: Jan 22, 2030
2 conditions2 sponsors5 locations
NCT07092254
Patterns of Care and Outcomes in Locally Recurrent Inoperable or Metastatic Triple-Negative Breast Cancer
N/ANot yet recruiting
760 participants
Started: Sep 1, 2025 · Completed: Apr 8, 2026
1 condition1 sponsor0 locations
NCT07098338
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
PHASE2Recruiting
278 participants
Started: Aug 7, 2025 · Completed: Apr 6, 2029
1 condition2 sponsors57 locations
NCT06780111
Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)
PHASE1/PHASE2Recruiting
228 participants
Started: Jul 30, 2025 · Completed: Jan 4, 2032
1 condition2 sponsors21 locations
NCT07060807
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
PHASE3Recruiting
1,000 participants
Started: Jul 21, 2025 · Completed: Jul 14, 2033
1 condition2 sponsors19 locations
NCT06824168
Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission
PHASE2Recruiting
130 participants
Started: Jul 18, 2025 · Completed: Jul 14, 2032
2 conditions1 sponsor57 locations
NCT07015697
A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors
PHASE1Recruiting
76 participants
Started: Jul 17, 2025 · Completed: Dec 31, 2028
1 condition2 sponsors5 locations
NCT06863272
A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)
PHASE1/PHASE2Recruiting
360 participants
Started: Jul 3, 2025 · Completed: Feb 24, 2030
2 conditions2 sponsors35 locations
NCT06750484
Trial of Trastuzumab Deruxtecan in Previously Treated HER2
PHASE2Recruiting
40 participants
Started: Jun 20, 2025 · Completed: Dec 31, 2028
1 condition3 sponsors1 location
NCT06973161
ESPERANZA: External Control Arm Study for T-DXd for Patients With HER2 IHC3+ Solid Tumors
N/ARecruiting
384 participants
Started: Jun 10, 2025 · Completed: Nov 3, 2025
9 conditions3 sponsors27 locations
NCT06780098
Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)
PHASE2Recruiting
144 participants
Started: May 28, 2025 · Completed: Mar 2, 2032
1 condition2 sponsors14 locations
NCT06941272
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
PHASE1/PHASE2Recruiting
50 participants
Started: May 26, 2025 · Completed: Dec 30, 2030
1 condition2 sponsors22 locations
NCT06780085
A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)
PHASE2Recruiting
96 participants
Started: May 13, 2025 · Completed: Mar 12, 2032
1 condition2 sponsors15 locations
NCT06925737
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
PHASE3Recruiting
1,440 participants
Started: May 13, 2025 · Completed: Jan 6, 2031
2 conditions2 sponsors216 locations
NCT06927895
Breast Cancer Implementation Science Study With Educational Intervention
NANot yet recruiting
30 participants
Started: Apr 30, 2025 · Completed: Dec 31, 2025
1 condition3 sponsors1 location
NCT06843447
A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)
PHASE1/PHASE2Recruiting
280 participants
Started: Apr 15, 2025 · Completed: Mar 27, 2029
1 condition2 sponsors15 locations
NCT06925100
A Study to Investigate the Effectiveness and Safety of Bempedoic Acid in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia in Taiwan
PHASE4Recruiting
180 participants
Started: Apr 1, 2025 · Completed: Nov 30, 2025
1 condition1 sponsor3 locations
NCT06864169
A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers (MK-5909-005)
PHASE2Recruiting
160 participants
Started: Apr 1, 2025 · Completed: Jan 4, 2029
1 condition2 sponsors41 locations
NCT06731907
A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)
PHASE2Recruiting
90 participants
Started: Mar 30, 2025 · Completed: Mar 12, 2032
1 condition2 sponsors33 locations
NCT06644781
A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)
PHASE3Recruiting
510 participants
Started: Mar 27, 2025 · Completed: Nov 1, 2029
1 condition2 sponsors46 locations
NCT06989112
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
PHASE3Recruiting
600 participants
Started: Mar 27, 2025 · Completed: Feb 19, 2031
1 condition4 sponsors244 locations
NCT06731803
Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma
PHASE1/PHASE2Recruiting
36 participants
Started: Mar 25, 2025 · Completed: Dec 31, 2027
1 condition2 sponsors11 locations
NCT06797635
Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
PHASE2Recruiting
372 participants
Started: Mar 20, 2025 · Completed: Dec 31, 2034
2 conditions2 sponsors12 locations
NCT06819007
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)
PHASE3Recruiting
582 participants
Started: Mar 19, 2025 · Completed: Jan 31, 2032
1 condition1 sponsor59 locations
NCT06610825
Castrate Resistant Prostate Cancer Enhertu Therapy
PHASE2Recruiting
60 participants
Started: Mar 5, 2025 · Completed: Oct 31, 2028
3 conditions4 sponsors1 location
NCT06222489
Whole Body HER3 Quantification With Radiolabelled Patritumab Deruxtecan (HER3-DXd) PET/CT
PHASE2Recruiting
16 participants
Started: Mar 3, 2025 · Completed: May 1, 2028
3 conditions2 sponsors1 location
NCT06846996
Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China
N/ARecruiting
260 participants
Started: Feb 27, 2025 · Completed: Jul 31, 2027
2 conditions1 sponsor36 locations
NCT06780137
A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)
PHASE1/PHASE2Recruiting
242 participants
Started: Feb 27, 2025 · Completed: Aug 31, 2029
1 condition2 sponsors28 locations
NCT06731478
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer
PHASE3Recruiting
726 participants
Started: Feb 27, 2025 · Completed: Feb 1, 2030
2 conditions2 sponsors245 locations
NCT06686394
Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
PHASE1/PHASE2Recruiting
81 participants
Started: Feb 26, 2025 · Completed: Sep 10, 2029
2 conditions2 sponsors14 locations
NCT06809764
Clinical Effectiveness and Safety of Trastuzumab Deruxtecan (T-DXd) in Chinese Patients With HER2m NSCLC (RERUN)
N/ARecruiting
150 participants
Started: Feb 21, 2025 · Completed: Feb 12, 2027
1 condition1 sponsor23 locations
NCT06686615
A Study of Bempedoic Acid in Combination With Ezetimibe and Either Rosuvastatin or Atorvastatin in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
N/ARecruiting
2,000 participants
Started: Feb 12, 2025 · Completed: Jan 31, 2028
2 conditions1 sponsor43 locations
NCT06925113
A Study to Investigate the Prevalence of Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemistry (IHC) 3+ and Characterize the Clinicopathologic Features of Gynecologic Cancers in Taiwan
N/ARecruiting
510 participants
Started: Jan 31, 2025 · Completed: Sep 30, 2025
3 conditions1 sponsor5 locations
NCT06807632
A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer
PHASE1Recruiting
24 participants
Started: Jan 29, 2025 · Completed: Jan 31, 2027
1 condition2 sponsors7 locations
NCT06812117
A Study to Evaluate the Safety and Effectiveness of Mirogabalin in Chinese Adult Patients With Diabetic Peripheral Neuropathic Pain (DPNP) in Real-world Clinical Practice Setting (ReMIssion Study)
N/ARecruiting
720 participants
Started: Jan 25, 2025 · Completed: Apr 13, 2026
1 condition1 sponsor30 locations
NCT06660654
A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors (REJOICE-PanTumor01)
PHASE2Recruiting
200 participants
Started: Jan 6, 2025 · Completed: Sep 30, 2027
2 conditions2 sponsors48 locations
NCT06402851
Vitamin K AntagonISt, Factor Xa Inhibitor or No Anticoagulation in Atrial Fibrillation and DIalytic End-stage Renal DiseasE (VISIONAIRE)
PHASE4Recruiting
1,500 participants
Started: Dec 18, 2024 · Completed: Dec 31, 2026
2 conditions2 sponsors6 locations
NCT06578247
Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
PHASE3Recruiting
700 participants
Started: Nov 19, 2024 · Completed: Jun 26, 2030
1 condition1 sponsor274 locations
NCT06644755
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
PHASE1Recruiting
150 participants
Started: Nov 14, 2024 · Completed: Nov 30, 2028
2 conditions1 sponsor7 locations
NCT06596694
Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)
PHASE1/PHASE2Recruiting
180 participants
Started: Nov 3, 2024 · Completed: Jul 24, 2028
1 condition2 sponsors62 locations
NCT06644768
A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations
PHASE1/PHASE2Recruiting
137 participants
Started: Oct 30, 2024 · Completed: Apr 30, 2030
2 conditions2 sponsors45 locations