A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

PHASE2RecruitingINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

May 13, 2025

Primary Completion Date

March 12, 2032

Study Completion Date

March 12, 2032

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL

Raludotatug Deruxtecan

IV Infusion

BIOLOGICAL

Ifinatamab Deruxtecan

IV Infusion

DRUG

Docetetaxel

IV Infusion

Trial Locations (15)

6000

RECRUITING

Bacs-Kiskun Varmegyei Oktatokorhaz ( Site 0063), Kecskemét

21237

RECRUITING

MedStar Franklin Square Medical Center ( Site 0033), Baltimore

28223

RECRUITING

Hospital Universitario Quiron Madrid ( Site 0091), Madrid

3109601

RECRUITING

Rambam Health Care Campus ( Site 0076), Haifa

4428164

RECRUITING

Meir Medical Center ( Site 0071), Kfar Saba

4941492

RECRUITING

Rabin Medical Center ( Site 0074), Petah Tikva

5265601

RECRUITING

Sheba Medical Center ( Site 0070), Ramat Gan

6423906

RECRUITING

Sourasky Medical Center ( Site 0077), Tel Aviv

7500653

RECRUITING

Centro de Estudios Clínicos SAGA ( Site 0161), Santiago

7500921

RECRUITING

FALP ( Site 0160), Santiago

8420383

RECRUITING

Bradfordhill ( Site 0162), Santiago

9103102

RECRUITING

Shaare Zedek Medical Center ( Site 0075), Jerusalem

40536-0293

RECRUITING

University of Kentucky Chandler Medical Center ( Site 0019), Lexington

60-569

RECRUITING

Wielkopolskie Centrum Pulmonologii i Torakochirurgii ( Site 0153), Poznan

80-214

RECRUITING

Uniwersyteckie Centrum Kliniczne-Early Clinical Trials Unit ( Site 0150), Gdansk

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Daiichi Sankyo

INDUSTRY

lead

Merck Sharp & Dohme LLC

INDUSTRY