686
Participants
Start Date
October 7, 2025
Primary Completion Date
March 5, 2030
Study Completion Date
July 5, 2032
Trastuzumab Deruxtecan
T-DXd will be administered at a dose of 5.4 mg/kg intravenously (IV) every 3 weeks (Q3W)
pembrolizumab
pembrolizumab will be administered at a dose of 200 mg IV Q3W
Pemetrexed
Pemetrexed will be administered at a dose of 500 mg/m2 IV Q3W
Chemotherapy
"One of the following two will be administered in Arm B:~Cisplatin at a dose of 75 mg/m2 IV or carboplatin AUC at a dose of 5 mg/mL/min IV"
RECRUITING
Clinical Research Alliance, Westbury
RECRUITING
BRCR Global Plantation, Plantation
RECRUITING
Lumi Research, Kingwood
RECRUITING
California Research Institute, Los Angeles
RECRUITING
Alaska Oncology & Hematology, LLC, Anchorage
RECRUITING
Nanfang Hospital of Southern Medical University, Guangzhou
RECRUITING
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou
RECRUITING
Shanghai East Hospital, Shanghai
RECRUITING
Saitama Medical University International Medical Center, Hidaka-shi
RECRUITING
Kansai Medical University Hospital, Hirakata-shi
RECRUITING
Hospital of the University of Occupational and Environmental Health, Kitakyushu-shi
RECRUITING
Saiseikai Kumamoto Hospital, Kumamoto
RECRUITING
Matsusaka Municipal Hospital, Matsusaka-shi
RECRUITING
NHO Kinki-Chuo Chest Medical Center, Sakaishi
RECRUITING
Keijinkai Teine Keijinkai Hospital, Sapporo
RECRUITING
Shizuoka Cancer Center, Sunto-gun
RECRUITING
Wakayama Medical University Hospital, Wakayama
RECRUITING
Kanagawa Cancer Center, Yokohama
RECRUITING
Tottori University Hospital, Yonago-shi
RECRUITING
Asan Medical Center, Seoul
RECRUITING
Samsung Medical Center, Seoul
RECRUITING
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City
RECRUITING
National Cheng Kung University Hospital, Tainan City
RECRUITING
Taipei Veterans General Hospital, Taipei
RECRUITING
Tri-Service General Hospital, Taipei
RECRUITING
Chang Gung Memorial Hospital,Linkou, Taoyuan
Lead Sponsor
Merck Sharp & Dohme LLC
INDUSTRY
Daiichi Sankyo
INDUSTRY