Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

PHASE2RecruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

July 18, 2025

Primary Completion Date

June 6, 2028

Study Completion Date

July 14, 2032

Conditions
Acute Myeloid LeukemiaLeukemia
Interventions
DRUG

Quizartinib High Dose

Participants in Arm 1 will receive oral daily higher dose of quizartinib,

DRUG

Quizartinib Low Dose

Participants in Arm 2 will receive oral daily lower dose of quizartinib

Trial Locations (57)

6591

NOT_YET_RECRUITING

The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul

10408

NOT_YET_RECRUITING

National Cancer Center, Goyang-si

10595

WITHDRAWN

Westchester Medical College, Valhalla

11590

RECRUITING

Clinical Research Allicance, Westbury

14263

WITHDRAWN

Roswell Park Cancer Institute, Buffalo

18045

NOT_YET_RECRUITING

Spoknwrd Clinical Trials Inc., Easton

21287

NOT_YET_RECRUITING

John Hopkins School of Medicine, Baltimore

77030

NOT_YET_RECRUITING

The Methodist Hospital Research Institute, Houston

NOT_YET_RECRUITING

The University of Texas MD Anderson Cancer Center, Houston

01655

NOT_YET_RECRUITING

Umass Memorial Health Care Systems, Worcester

10021-9800

NOT_YET_RECRUITING

Weill Cornell, New York

Unknown

NOT_YET_RECRUITING

Royal Adelaide Hospital, Adelaide

NOT_YET_RECRUITING

Austin Health, Australia

NOT_YET_RECRUITING

St. Vincent's Hospital Melbourne, Darlinghurst

NOT_YET_RECRUITING

The Alfred Hospital, Melbourne

NOT_YET_RECRUITING

Royal Perth Hospital, Perth

NOT_YET_RECRUITING

Gold Coast University Hospital, Southport

NOT_YET_RECRUITING

Westmead Hospital, Sydney

NOT_YET_RECRUITING

Hospital Erasto Gaertner - Liga Paranaense de Combate ao Cancer, Curitiba

NOT_YET_RECRUITING

Cetus Hospital Dia Oncologia, Minas Gerai

NOT_YET_RECRUITING

Hospital de Clínicas de Porto Alegre, Porto Alegre

RECRUITING

Irmandade da Santa Casa de Misericórdia de Porto Alegre Centro Multidisciplinar de Pesquisa, Porto Alegre

NOT_YET_RECRUITING

INCA - Instituto Nacional de Câncer, Rio de Janeiro

NOT_YET_RECRUITING

"Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto CIP - Centro Integrado de Pesquisa", San Jose Rio Preto

NOT_YET_RECRUITING

Hospital Santa Marcelina, São Paulo

NOT_YET_RECRUITING

ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, São Paulo

NOT_YET_RECRUITING

Peking Union Medical College Hospital, Beijing

NOT_YET_RECRUITING

Peking University Third Hospital, Beijing

NOT_YET_RECRUITING

The First Hospital of Jilin University, Changchun

NOT_YET_RECRUITING

Guangdong Provincial People's Hospital, Guangzhou

NOT_YET_RECRUITING

Nanfang Hospital of Southern Medical University, Guangzhou

NOT_YET_RECRUITING

Sun Yat-sen University Cancer center, Guangzhou

NOT_YET_RECRUITING

The First Affiliated Hosptial of Zhejiang University School of Medicine, Hangzhou

NOT_YET_RECRUITING

The First Affiliated Hospital of Nanchang University, Nanchang

NOT_YET_RECRUITING

Zhong Da Hospital, Southeast University, Nanjing

NOT_YET_RECRUITING

The First Affiliated Hospital of Guangxi Medical University, Nanning

NOT_YET_RECRUITING

The Affiliated Hospital of Qingdao University, Qingdao

NOT_YET_RECRUITING

Huashan Hospital, Fudan University, Shanghai

NOT_YET_RECRUITING

The First Affiliated Hospital of Soochow University, Suzhou

NOT_YET_RECRUITING

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou

NOT_YET_RECRUITING

The First Affiliated Hospital of Jiaotong University, Xi'an

NOT_YET_RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

NOT_YET_RECRUITING

The Affiliated Hospital of Xuzhou Medical College, Xuzhou

NOT_YET_RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

RECRUITING

Inje University Haeundae Paik Hospital, Busan

RECRUITING

Pusan National University Hospital, Busan

NOT_YET_RECRUITING

Kyungpook National University Hospital, Daegu

NOT_YET_RECRUITING

Yeungnam University Hospital, Daegu

RECRUITING

Gachon University Gil Medical Center, Incheon

RECRUITING

Jeonbuk National University Hospital, Jeonju

RECRUITING

Seoul National University Bundang Hospital, Seongnam

NOT_YET_RECRUITING

Samsung Medical Center, Seoul

NOT_YET_RECRUITING

Seoul National University Hospital, Seoul

NOT_YET_RECRUITING

Severance Hospital, Yonsei University Health System, Seoul

NOT_YET_RECRUITING

The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul

NOT_YET_RECRUITING

Ajou University Hospital, Suwon

RECRUITING

Ulsan University Hospital, Ulsan

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Daiichi Sankyo

INDUSTRY