Clinical Trials for BeiGene

Explore 118 clinical trials worldwide

Showing 1-50 of 118 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: BeiGene

Clinical Trials (118)

NCT07205731
Phase II Study Evaluating Safety and Efficacy of Tislelizumab for Elderly Patients Unfit for Chemotherapy, With Advanced Esophageal Squamous-cell Carcinoma
PHASE2Not yet recruiting
95 participants
Started: Oct 31, 2025 · Completed: Oct 31, 2030
1 condition3 sponsors10 locations
NCT07181681
A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors
PHASE1Not yet recruiting
63 participants
Started: Oct 22, 2025 · Completed: Nov 1, 2027
2 conditions1 sponsor0 locations
NCT07169331
A Study to Evaluate the Efficacy and Safety of Zanubrutinib in Chinese Adults With Treatment-Naive Waldenström Macroglobulinemia
PHASE4Not yet recruiting
18 participants
Started: Oct 15, 2025 · Completed: Oct 31, 2028
1 condition1 sponsor0 locations
NCT07141511
A Study to Investigate the Relative Bioavailability and Food Effect of a Fixed-Dose Combination Tablet Containing Zanubrutinib and Sonrotoclax (BG-71332) in Healthy Adults
PHASE1Not yet recruiting
24 participants
Started: Sep 30, 2025 · Completed: Jan 3, 2026
1 condition1 sponsor0 locations
NCT07136077
A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
PHASE2Active, not recruiting
20 participants
Started: Sep 18, 2025 · Completed: Apr 1, 2028
6 conditions3 sponsors1 location
NCT06973187
A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
PHASE3Recruiting
500 participants
Started: Sep 4, 2025 · Completed: Apr 17, 2028
2 conditions1 sponsor1 location
NCT06854003
BRAZAN Trial in Frontline MCL
PHASE2Not yet recruiting
60 participants
Started: Aug 31, 2025 · Completed: Nov 1, 2039
2 conditions2 sponsors2 locations
NCT07059299
A Phase Ib Trial Evaluating the Safety and Activity of Neoadjuvant Combination of Tislelizumab Plus FLOT for Resectable Esophagogastric Adenocarcinoma
PHASE1Not yet recruiting
18 participants
Started: Aug 31, 2025 · Completed: Aug 31, 2027
5 conditions3 sponsors1 location
NCT07043400
A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
PHASE3Recruiting
351 participants
Started: Aug 27, 2025 · Completed: Apr 22, 2028
2 conditions1 sponsor95 locations
NCT07100938
A Study Investigating the Efficacy and Safety of BGB-45035 Versus Placebo in Adults With Moderate to Severe Active Rheumatoid Arthritis
PHASE2Recruiting
90 participants
Started: Aug 21, 2025 · Completed: Oct 18, 2026
1 condition1 sponsor29 locations
NCT07005713
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple-Ascending Doses of BGB-16673 in Adults With Chronic Spontaneous Urticaria
PHASE1Recruiting
27 participants
Started: Jul 19, 2025 · Completed: Sep 22, 2026
1 condition1 sponsor10 locations
NCT07039162
Study of Tislelizumab Combined With Chemoradiotherapy and Surgery for Unresectable Esophageal Squamous Cell Carcinoma
PHASE2Not yet recruiting
45 participants
Started: Jul 1, 2025 · Completed: Dec 31, 2028
2 conditions2 sponsors4 locations
NCT06943872
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
PHASE3Recruiting
630 participants
Started: Jun 11, 2025 · Completed: Dec 31, 2032
2 conditions2 sponsors178 locations
NCT06839053
Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma
PHASE2Recruiting
20 participants
Started: Jun 2, 2025 · Completed: Jul 1, 2032
9 conditions2 sponsors1 location
NCT06547866
Study Evaluating the Efficacy and Tolerance of a Zanubrutinib and BGB-11417 Combination in Patients Previously Treated for Waldenström Macroglobulinemia
PHASE2Not yet recruiting
102 participants
Started: Jun 1, 2025 · Completed: Dec 31, 2031
1 condition2 sponsors37 locations
NCT07012980
Glofitamab, Polatuzumab Vedotin and Zanubrutinib in First-line Elderly DLBCL
PHASE2Not yet recruiting
38 participants
Started: Jun 1, 2025 · Completed: Jul 31, 2026
1 condition3 sponsors0 locations
NCT06970743
A Study of BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) Inhibitors
PHASE3Recruiting
150 participants
Started: May 29, 2025 · Completed: Nov 30, 2029
2 conditions1 sponsor64 locations
NCT06730542
Zanubrutinib in Combination With Pola-R-CHP and High-dose Methotrexate in Patients With Secondary CNS Lymphoma
PHASE1Recruiting
20 participants
Started: Apr 17, 2025 · Completed: Apr 30, 2030
1 condition2 sponsors1 location
NCT06332274
tislelizUMaB in canceR Patients With molEcuLar residuaL Disease
PHASE3Recruiting
717 participants
Started: Apr 16, 2025 · Completed: Apr 30, 2030
5 conditions3 sponsors1 location
NCT06846671
A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
PHASE3Recruiting
250 participants
Started: Apr 10, 2025 · Completed: Feb 14, 2030
2 conditions1 sponsor125 locations
NCT06906809
Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants
PHASE1Recruiting
30 participants
Started: Apr 3, 2025 · Completed: Oct 13, 2025
1 condition1 sponsor1 location
NCT06803680
A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors
PHASE1Recruiting
90 participants
Started: Mar 18, 2025 · Completed: Oct 30, 2027
2 conditions1 sponsor13 locations
NCT06742996
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma
PHASE3Recruiting
300 participants
Started: Mar 5, 2025 · Completed: Oct 30, 2032
2 conditions1 sponsor148 locations
NCT06558604
A Phase II Study Evaluating Glofitamab in Combination With Venetoclax Plus Zanubrutinib or Venetoclax Alone in Subjects With Untreated or Relapsed/Refractory High-risk Mantle-cell Lymphoma
PHASE2Recruiting
100 participants
Started: Feb 28, 2025 · Completed: Mar 31, 2032
1 condition3 sponsors17 locations
NCT06685887
A Clinical Study Evaluating the Efficacy of Systemic Chemotherapy and Immune Checkpoint Inhibitors Combined With Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Gastric Cancer Patients With Peritoneal Metastasis
PHASE2Recruiting
34 participants
Started: Feb 15, 2025 · Completed: Dec 31, 2027
1 condition2 sponsors1 location
NCT06756932
BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer
PHASE1Recruiting
120 participants
Started: Feb 4, 2025 · Completed: Jul 30, 2027
3 conditions1 sponsor16 locations
NCT06764355
Neoadjuvant Immunochemotherapy and Chemoradiotherapy Followed by Surgery for Advanced Esophageal Squamous Cell Carcinoma
PHASE2Not yet recruiting
50 participants
Started: Jan 31, 2025 · Completed: Dec 31, 2028
3 conditions2 sponsors0 locations
NCT06697184
A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.
PHASE1/PHASE2Recruiting
56 participants
Started: Jan 23, 2025 · Completed: Dec 31, 2027
2 conditions1 sponsor16 locations
NCT06563596
Epco, Zanu, Ritux for R/R FL or MZL
PHASE2Recruiting
45 participants
Started: Jan 21, 2025 · Completed: Mar 1, 2030
6 conditions3 sponsors2 locations
NCT06561347
Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM
PHASE2Recruiting
55 participants
Started: Dec 20, 2024 · Completed: Dec 1, 2027
1 condition2 sponsors3 locations
NCT06625593
A First-in-Human Study of BG-C137, an Anti-FGFR2b Antibody Drug Conjugate, in Participants With Advanced Solid Tumors
PHASE1Recruiting
68 participants
Started: Dec 9, 2024 · Completed: Dec 31, 2026
1 condition1 sponsor24 locations
NCT06634589
A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies
PHASE1/PHASE2Recruiting
80 participants
Started: Nov 27, 2024 · Completed: Dec 2, 2029
4 conditions1 sponsor50 locations
NCT06585488
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification
PHASE1Recruiting
514 participants
Started: Nov 26, 2024 · Completed: Dec 31, 2026
7 conditions1 sponsor17 locations
NCT06685718
A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer
PHASE1Recruiting
93 participants
Started: Nov 26, 2024 · Completed: Apr 30, 2028
6 conditions1 sponsor42 locations
NCT06520683
Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer
PHASE3Recruiting
180 participants
Started: Nov 1, 2024 · Completed: Nov 1, 2030
2 conditions2 sponsors1 location
NCT06630871
A Clinical Trial Evaluating the Efficacy and Safety of Disitamab Vedotin Plus Tislelizumab Combined with Re-TURBT in the Treatment of HER-2-high Expression(2+-3+) Non-muscle Invasive Bladder Cancer At High-risk and Very High-risk.
PHASE2Not yet recruiting
40 participants
Started: Oct 31, 2024 · Completed: Oct 31, 2028
1 condition3 sponsors1 location
NCT06598800
Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors
PHASE1Recruiting
87 participants
Started: Oct 18, 2024 · Completed: Jan 31, 2028
1 condition1 sponsor29 locations
NCT06589596
An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors
PHASE1Recruiting
237 participants
Started: Oct 11, 2024 · Completed: Jun 30, 2027
1 condition1 sponsor45 locations
NCT06596473
A Study of BG-C477 in Participants With Advanced Solid Tumors
PHASE1Recruiting
21 participants
Started: Oct 3, 2024 · Completed: Oct 27, 2028
1 condition1 sponsor21 locations
NCT06497062
Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemia
PHASE2Not yet recruiting
47 participants
Started: Sep 4, 2024 · Completed: Jun 30, 2028
1 condition3 sponsors1 location
NCT06540066
A Study of BGB-B3227 Alone and in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors
PHASE1Recruiting
75 participants
Started: Aug 30, 2024 · Completed: Jan 31, 2027
4 conditions1 sponsor12 locations
NCT06529523
Tislelizumab in People With Colorectal Cancer
PHASE2Recruiting
40 participants
Started: Jul 26, 2024 · Completed: Jul 31, 2028
1 condition2 sponsors3 locations
NCT06427941
A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors
PHASE1Recruiting
140 participants
Started: Jul 23, 2024 · Completed: Oct 30, 2026
6 conditions1 sponsor15 locations
NCT06487858
A Study of BGB-R046 as Monotherapy and in Combination With Tislelizumab in Solid Tumors
PHASE1Recruiting
74 participants
Started: Jul 16, 2024 · Completed: Dec 31, 2027
1 condition1 sponsor8 locations
NCT06422520
A First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in Participants With Advanced Solid Tumors
PHASE1Recruiting
120 participants
Started: Jul 8, 2024 · Completed: Jan 31, 2027
1 condition1 sponsor15 locations
NCT06093061
Tislelizumab and Metronomic Capecitabine as Maintenance in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma
PHASE2Recruiting
69 participants
Started: Jul 3, 2024 · Completed: Oct 31, 2029
1 condition3 sponsors2 locations
NCT06456138
Trametinib Plus Anlotinib Combined With Tislelizumab in KRAS-mutant NSCLC
PHASE1/PHASE2Not yet recruiting
60 participants
Started: Jul 1, 2024 · Completed: Dec 31, 2028
3 conditions4 sponsors1 location
NCT06342713
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases
PHASE1Recruiting
211 participants
Started: Jun 3, 2024 · Completed: May 23, 2026
7 conditions1 sponsor12 locations
NCT05635162
Zanubrutinib Plus Rituximab for Patients With Indolent Mantle Cell Lymphoma
PHASE2Recruiting
50 participants
Started: May 17, 2024 · Completed: Oct 31, 2028
1 condition2 sponsors13 locations
NCT06029309
Zanubrutinib and Tafasitamab in Mantle Cell Lymphoma
PHASE1/PHASE2Recruiting
27 participants
Started: May 3, 2024 · Completed: May 1, 2032
1 condition4 sponsors1 location