Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM

PHASE2RecruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

December 20, 2024

Primary Completion Date

December 1, 2026

Study Completion Date

December 1, 2027

Conditions
Waldenstrom Macroglobulinemia
Interventions
DRUG

Zanubrutinib

A potent, specific, and irreversible Bruton tyrosine kinase (BTK) inhibitor

DRUG

Bendamustine

Alkylating agent

DRUG

Rituximab

Monoclonal antibody

Trial Locations (3)

02114

RECRUITING

Massachusetts General Hospital, Boston

02215

RECRUITING

Beth Israel Deaconess Medical Center, Boston

RECRUITING

Dana Farber Cancer Institute, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

BeiGene

INDUSTRY

lead

Massachusetts General Hospital

OTHER

NCT06561347 - Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM | Biotech Hunter | Biotech Hunter