tislelizUMaB in canceR Patients With molEcuLar residuaL Disease

PHASE3RecruitingINTERVENTIONAL
Enrollment

717

Participants

Timeline

Start Date

April 16, 2025

Primary Completion Date

April 30, 2029

Study Completion Date

April 30, 2030

Conditions
CancerLung CancerColo-rectal CancerPancreas CancerSoft Tissue Sarcoma
Interventions
DRUG

Tislelizumab

"Formulation : 100 mg of antibody in 10 mL of isotonic solution (25 mM citrate buffer, 15 mM L-histidine/histidine hydrochloride, 190 mM trehalose-dihydrate, and 0.02% polysorbate 20 at pH 6.5) in a single-use vial.~Dose Regimen: Tislelizumab 400 mg every 6 weeks (Q6W) for a maximum of 9 cycles, on the first day of each cycle, in IV."

OTHER

Blood sampling

Blood sampling for analyses of MRD (Molecular Residual Disease)

DRUG

Placebo

"Pharmaceutical form : Solvent IV bags used for dilution of tislelizumab (for example: CHLORURE DE SODIUM FRESENIUS 0,9 %, solution injectable) Dose Regimen: every 6 weeks (Q6W) for a maximum of 9 cycles, on the first day of each cycle, in IV."

Trial Locations (1)

94800

RECRUITING

Gustave Roussy, Villejuif

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

BeiGene

INDUSTRY

collaborator

Veracyte, Inc.

INDUSTRY

lead

Gustave Roussy, Cancer Campus, Grand Paris

OTHER

NCT06332274 - tislelizUMaB in canceR Patients With molEcuLar residuaL Disease | Biotech Hunter | Biotech Hunter