Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

November 1, 2024

Primary Completion Date

November 1, 2027

Study Completion Date

November 1, 2030

Conditions
Colorectal CancerMicrosatellite Instability High
Interventions
DRUG

Tislelizumab

\- Tislelizumab 200mg (day 1 and day 22), administered after surgery

DRUG

Adjuvant chemotherapy

"* Adjuvant therapy is not mandatory.~* Optional adjuvant regimens include FOLFOX, CapeOX, 5-FU+LV, or Capecitabine."

Trial Locations (1)

510060

RECRUITING

Dept. of Colorectal Surgery, Sun Yat-sen University Cancer Center. Yuexiu District, Dongfeng East Road 651, Guangzhou

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

BeiGene

INDUSTRY

lead

Sun Yat-sen University

OTHER

NCT06520683 - Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer | Biotech Hunter | Biotech Hunter