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Clinical Trials for Jazz Pharmaceuticals
Explore 51 clinical trials worldwide
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Showing 1-50 of 51 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Jazz Pharmaceuticals
Clinical Trials (51)
NCT06924827
"A Study to Investigate the Transition of Children From 'Artisanal Cannabidiol (CBD) to Epidiolex"
PHASE4
Not yet recruiting
25 participants
Started: Feb 2, 2026 · Completed: Dec 31, 2028
2 conditions
4 sponsors
1 location
NCT06738368
Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia
PHASE2
Not yet recruiting
30 participants
Started: Dec 1, 2025 · Completed: Jun 30, 2028
2 conditions
2 sponsors
1 location
NCT07153055
Phase I/II Trial of Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer
PHASE1/PHASE2
Not yet recruiting
16 participants
Started: Nov 30, 2025 · Completed: Oct 31, 2029
2 conditions
2 sponsors
1 location
NCT07192068
Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.
PHASE2
Not yet recruiting
105 participants
Started: Oct 20, 2025 · Completed: Jun 24, 2030
5 conditions
3 sponsors
1 location
NCT07102381
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
PHASE2
Recruiting
125 participants
Started: Sep 24, 2025 · Completed: Aug 1, 2030
2 conditions
2 sponsors
10 locations
NCT06113237
Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy
N/A
Recruiting
50 participants
Started: Aug 5, 2025 · Completed: Aug 31, 2033
4 conditions
1 sponsor
1 location
NCT06961266
A Study to Investigate Efficacy, Safety, Tolerability, and Pharmacokinetics of JZP441 Compared With Placebo in Participants With Narcolepsy Type 1
PHASE1
Recruiting
8 participants
Started: May 13, 2025 · Completed: Apr 1, 2026
1 condition
2 sponsors
4 locations
NCT06261502
Effect of CANnabidiol on Anxiety and GABAergic Function in Individuals with Fragile-X Syndrome
PHASE2
Not yet recruiting
40 participants
Started: May 1, 2025 · Completed: Dec 1, 2027
1 condition
4 sponsors
0 locations
NCT06261450
Effect of CBD on the Brain
PHASE2
Not yet recruiting
50 participants
Started: May 1, 2025 · Completed: Dec 15, 2027
1 condition
4 sponsors
0 locations
NCT05485831
Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY
N/A
Recruiting
100 participants
Started: Feb 24, 2025 · Completed: Jan 31, 2026
3 conditions
2 sponsors
18 locations
NCT06695845
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
PHASE2
Recruiting
200 participants
Started: Jan 14, 2025 · Completed: Dec 31, 2027
12 conditions
2 sponsors
21 locations
NCT06435429
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
PHASE3
Recruiting
550 participants
Started: Aug 13, 2024 · Completed: Nov 26, 2031
1 condition
1 sponsor
163 locations
NCT06282575
Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer
PHASE3
Recruiting
286 participants
Started: Jul 19, 2024 · Completed: Apr 1, 2030
1 condition
1 sponsor
183 locations
NCT06043427
Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma
PHASE2
Recruiting
168 participants
Started: Apr 16, 2024 · Completed: Jun 30, 2026
1 condition
2 sponsors
18 locations
NCT06143839
VYxeoS Liposomal Italian Observational Study iN the Real Practice
N/A
Active, not recruiting
112 participants
Started: Dec 7, 2023 · Completed: Feb 1, 2026
3 conditions
2 sponsors
24 locations
NCT06108050
JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors
PHASE1
Recruiting
177 participants
Started: Nov 7, 2023 · Completed: May 31, 2028
2 conditions
2 sponsors
10 locations
NCT05850676
Disentangling the Role of Depression in Hypersomnia
N/A
Recruiting
45 participants
Started: Aug 1, 2023 · Completed: Jun 30, 2026
1 condition
2 sponsors
1 location
NCT05918640
Lurbinectedin in FET-Fused Tumors
PHASE1/PHASE2
Recruiting
63 participants
Started: Jul 27, 2023 · Completed: Jul 30, 2028
4 conditions
3 sponsors
6 locations
NCT05636111
Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer
PHASE1
Recruiting
34 participants
Started: Jul 12, 2023 · Completed: Dec 31, 2026
1 condition
2 sponsors
1 location
NCT05864846
A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex
PHASE4
Active, not recruiting
79 participants
Started: Jun 29, 2023 · Completed: Mar 26, 2026
1 condition
1 sponsor
19 locations
NCT05734066
Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma
PHASE1/PHASE2
Recruiting
60 participants
Started: May 23, 2023 · Completed: Jun 1, 2027
3 conditions
1 sponsor
15 locations
NCT04990102
Phase IB/II of CPX-351 for Relapse Prevention in AML
PHASE1/PHASE2
Recruiting
24 participants
Started: May 22, 2023 · Completed: Dec 31, 2025
1 condition
3 sponsors
3 locations
NCT05260528
CPX-351 vs Intensive Chemotherapy in Patients With de Novo Intermediate or Adverse Risk AML Stratified by Genomics
PHASE2
Recruiting
210 participants
Started: May 3, 2023 · Completed: Oct 31, 2027
1 condition
3 sponsors
30 locations
NCT05772429
Long-Term Follow-Up of a Cohort of Participants Prescribed Epidyolex in France in a Real-life Setting
N/A
Active, not recruiting
158 participants
Started: Apr 17, 2023 · Completed: Jul 31, 2026
1 condition
1 sponsor
29 locations
NCT05558124
CPX-351 in Combination With Gemtuzumab Ozogamicin in Newly Diagnosed AML
PHASE1
Recruiting
18 participants
Started: Feb 16, 2023 · Completed: Nov 30, 2025
1 condition
2 sponsors
1 location
NCT05629702
ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids
PHASE2
Recruiting
120 participants
Started: Feb 3, 2023 · Completed: Apr 30, 2027
4 conditions
4 sponsors
22 locations
NCT05580562
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
PHASE3
Recruiting
450 participants
Started: Jan 23, 2023 · Completed: Aug 31, 2026
2 conditions
1 sponsor
162 locations
NCT05656248
Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms
PHASE2
Active, not recruiting
25 participants
Started: Jan 17, 2023 · Completed: Aug 31, 2028
1 condition
2 sponsors
1 location
NCT05557045
A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815
PHASE1
Recruiting
332 participants
Started: Oct 10, 2022 · Completed: Apr 1, 2028
3 conditions
1 sponsor
8 locations
NCT05476939
Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0
PHASE3
Recruiting
409 participants
Started: Sep 29, 2022 · Completed: Sep 30, 2031
2 conditions
4 sponsors
42 locations
NCT05244239
Palliative Radiotherapy with Lurbinectedin in Patients with Extensive Stage Small Cell Lung Cancer
PHASE1
Recruiting
22 participants
Started: Jul 27, 2022 · Completed: Jul 28, 2025
2 conditions
3 sponsors
3 locations
NCT05024552
Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML
PHASE1
Recruiting
22 participants
Started: Feb 25, 2022 · Completed: Mar 31, 2027
1 condition
2 sponsors
1 location
NCT05099666
Lurbinectedin + Doxorubicin In Leiomyosarcoma
PHASE1/PHASE2
Active, not recruiting
62 participants
Started: Feb 4, 2022 · Completed: Jul 31, 2027
4 conditions
2 sponsors
6 locations
NCT05152147
A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers
PHASE3
Active, not recruiting
920 participants
Started: Dec 2, 2021 · Completed: May 15, 2026
3 conditions
3 sponsors
226 locations
NCT05091567
A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer
PHASE3
Active, not recruiting
660 participants
Started: Nov 18, 2021 · Completed: Aug 13, 2026
1 condition
2 sponsors
92 locations
NCT04732065
ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors
PHASE1
Recruiting
208 participants
Started: Aug 23, 2021 · Completed: Jul 31, 2027
8 conditions
7 sponsors
5 locations
NCT04269213
CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old
PHASE2
Recruiting
46 participants
Started: Jul 29, 2021 · Completed: Jan 29, 2027
4 conditions
2 sponsors
4 locations
NCT05044819
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
PHASE4
Active, not recruiting
154 participants
Started: Jul 7, 2021 · Completed: Mar 31, 2028
3 conditions
2 sponsors
19 locations
NCT04652115
Defibrotide for the Treatment of Severe COVID-19
PHASE2
Recruiting
42 participants
Started: Jan 1, 2021 · Completed: Mar 1, 2025
1 condition
2 sponsors
1 location
NCT07156435
Vyxeos® With Clofarabine for Pediatric AML
PHASE1
Recruiting
25 participants
Started: Nov 6, 2020 · Completed: Dec 31, 2028
2 conditions
2 sponsors
13 locations
NCT04541082
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
PHASE1
Recruiting
102 participants
Started: Oct 26, 2020 · Completed: Dec 31, 2026
23 conditions
2 sponsors
1 location
NCT04899947
Child and Adolescent Registry for Participants With Narcolepsy
N/A
Recruiting
500 participants
Started: Oct 10, 2020 · Completed: Oct 1, 2024
1 condition
1 sponsor
25 locations
NCT05826756
Project PEER: Understanding the Lung Cancer Patient ExperiEnce in the Real-World Setting
N/A
Recruiting
1,300 participants
Started: Aug 15, 2020 · Completed: Dec 31, 2025
2 conditions
14 sponsors
1 location
NCT04195945
CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients
PHASE2
Active, not recruiting
60 participants
Started: Mar 11, 2020 · Completed: Dec 31, 2027
2 conditions
2 sponsors
1 location
NCT04231851
CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia
PHASE2
Active, not recruiting
30 participants
Started: Feb 19, 2020 · Completed: Jun 30, 2027
2 conditions
3 sponsors
4 locations
NCT03897127
Study of Standard Intensive Chemotherapy Versus Intensive Chemotherapy With CPX-351 in Adult Patients With Newly Diagnosed AML and Intermediate- or Adverse Genetics
PHASE3
Active, not recruiting
882 participants
Started: Sep 4, 2019 · Completed: Jun 30, 2027
1 condition
2 sponsors
62 locations
NCT03825796
CPX-351 Plus Enasidenib for Relapsed AML
PHASE2
Active, not recruiting
2 participants
Started: Apr 12, 2019 · Completed: Sep 1, 2024
1 condition
2 sponsors
3 locations
NCT03202303
Cannabidivarin (CBDV) vs. Placebo in Children With Autism Spectrum Disorder (ASD)
PHASE2
Recruiting
100 participants
Started: Apr 12, 2019 · Completed: Feb 28, 2027
1 condition
4 sponsors
2 locations
NCT03865589
Using Ultrasound Elastography to Predict Development of Hepatic Sinusoidal Obstruction Syndrome
NA
Active, not recruiting
250 participants
Started: Apr 1, 2019 · Completed: Jun 30, 2027
4 conditions
7 sponsors
7 locations
NCT03572764
CPX-351 (Vyxeos™) for Transplant Eligible, Higher Risk Patients With Myelodysplastic Syndrome
PHASE1
Active, not recruiting
20 participants
Started: Dec 14, 2018 · Completed: Mar 25, 2027
1 condition
2 sponsors
3 locations
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