Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

October 20, 2025

Primary Completion Date

March 13, 2028

Study Completion Date

June 24, 2030

Conditions
Non-Small Cell Lung CancerSarcomaHead &Amp; Neck CancerColorectal CarcinomaEndometrial
Interventions
DRUG

Zanidatamab

"Single arm study where the experimental regimen used for all patients will be zanidatamab, administered intravenously every 3 weeks :~* Patients \<70 kg: 1800 mg IV Q3W on Day 1 of each 21-day cycle~* Patients ≥70 kg: 2400 mg IV Q3W on Day 1 of each 21-day cycle."

Trial Locations (1)

Unknown

Gustave Roussy, Villejuif

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Cancer Institute, France

OTHER_GOV

collaborator

Jazz Pharmaceuticals

INDUSTRY

lead

UNICANCER

OTHER