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Clinical Trials for Incyte
Explore 157 clinical trials worldwide
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Showing 1-50 of 157 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Incyte
Clinical Trials (157)
NCT06551584
Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT
PHASE1
Not yet recruiting
24 participants
Started: Jan 31, 2026 · Completed: Dec 31, 2026
4 conditions
2 sponsors
1 location
NCT07128381
Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)
PHASE1/PHASE2
Not yet recruiting
66 participants
Started: Jan 31, 2026 · Completed: Jul 31, 2033
2 conditions
2 sponsors
1 location
NCT07219576
Retifanlimab and Ruxolitinib In Solid Malignancies
PHASE1/PHASE2
Not yet recruiting
40 participants
Started: Dec 31, 2025 · Completed: Dec 31, 2029
2 conditions
2 sponsors
1 location
NCT07195916
A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies
PHASE1
Not yet recruiting
280 participants
Started: Dec 31, 2025 · Completed: Aug 18, 2028
2 conditions
1 sponsor
0 locations
NCT07124078
A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
PHASE2
Not yet recruiting
60 participants
Started: Dec 15, 2025 · Completed: Jul 31, 2029
1 condition
1 sponsor
0 locations
NCT07213973
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
PHASE2
Not yet recruiting
40 participants
Started: Dec 14, 2025 · Completed: Mar 25, 2028
1 condition
1 sponsor
0 locations
NCT07214779
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
PHASE3
Not yet recruiting
466 participants
Started: Dec 1, 2025 · Completed: May 14, 2029
1 condition
3 sponsors
0 locations
NCT06728410
A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement
PHASE2
Not yet recruiting
38 participants
Started: Nov 30, 2025 · Completed: Jul 31, 2027
3 conditions
4 sponsors
1 location
NCT07023627
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
PHASE2
Recruiting
160 participants
Started: Nov 15, 2025 · Completed: Oct 24, 2027
1 condition
2 sponsors
82 locations
NCT07218744
Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB123667 in Healthy Male Participants
PHASE1
Not yet recruiting
9 participants
Started: Nov 13, 2025 · Completed: Dec 8, 2025
1 condition
1 sponsor
0 locations
NCT06906562
A Phase II Nationwide, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations
PHASE2
Recruiting
40 participants
Started: Nov 1, 2025 · Completed: Dec 31, 2026
5 conditions
2 sponsors
71 locations
NCT06233110
Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD
PHASE1
Recruiting
30 participants
Started: Oct 31, 2025 · Completed: Jul 1, 2029
1 condition
4 sponsors
1 location
NCT06616155
Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer
PHASE1/PHASE2
Recruiting
39 participants
Started: Oct 30, 2025 · Completed: Oct 30, 2029
3 conditions
2 sponsors
3 locations
NCT07104565
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
PHASE2
Not yet recruiting
56 participants
Started: Oct 15, 2025 · Completed: Mar 9, 2028
1 condition
1 sponsor
0 locations
NCT07049575
Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa
PHASE1
Recruiting
24 participants
Started: Oct 15, 2025 · Completed: Dec 9, 2026
1 condition
1 sponsor
20 locations
NCT06804811
A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Children (6 to < 12 Years Old) With Nonsegmental Vitiligo
PHASE3
Recruiting
250 participants
Started: Oct 15, 2025 · Completed: Dec 1, 2027
1 condition
1 sponsor
2 locations
NCT07085039
Ruxolitinib in Previously Treated Idiopathic Multicentric Castleman Disease
PHASE2
Recruiting
14 participants
Started: Oct 15, 2025 · Completed: Dec 31, 2028
2 conditions
3 sponsors
1 location
NCT07008118
A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms
PHASE1
Recruiting
120 participants
Started: Oct 1, 2025 · Completed: Dec 14, 2029
1 condition
1 sponsor
17 locations
NCT07015853
ASTRAEA: ReinvigorAting ReSponse To ImmunotheRApy in MEtAstatic TNBC With Combination Myeloid Inhibition and Radiation
PHASE2
Not yet recruiting
34 participants
Started: Sep 30, 2025 · Completed: Dec 31, 2032
2 conditions
3 sponsors
1 location
NCT06752694
Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia
PHASE2
Recruiting
20 participants
Started: Sep 25, 2025 · Completed: Jun 1, 2027
1 condition
2 sponsors
1 location
NCT06896188
9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With Advanced Pancreatic Adenocarcinoma (RiLEY)
PHASE1
Recruiting
12 participants
Started: Sep 22, 2025 · Completed: Dec 31, 2028
1 condition
3 sponsors
1 location
NCT06218082
Vitiligo Registry for Adults and Children in the UK
N/A
Not yet recruiting
30 participants
Started: Sep 15, 2025 · Completed: Jul 31, 2029
2 conditions
2 sponsors
1 location
NCT06991101
Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma
PHASE2
Not yet recruiting
190 participants
Started: Aug 31, 2025 · Completed: Jul 31, 2031
7 conditions
2 sponsors
1 location
NCT07030699
A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma
PHASE2
Recruiting
27 participants
Started: Aug 13, 2025 · Completed: Aug 31, 2028
1 condition
3 sponsors
7 locations
NCT06792825
HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL
PHASE2
Recruiting
65 participants
Started: Aug 7, 2025 · Completed: Jul 8, 2031
2 conditions
2 sponsors
1 location
NCT07126236
Response-adaptive to Epcoritamab In First Relapse: Study to Evaluate the Efficacy of Eptoritamab in Patients With Relapse/Refractory Large B Cell Lymphoma
PHASE2
Recruiting
80 participants
Started: Aug 4, 2025 · Completed: Dec 31, 2031
1 condition
4 sponsors
15 locations
NCT07011810
Axatilimab for Sclerotic Chronic Graft-versus-Host Disease
PHASE2
Recruiting
50 participants
Started: Jul 31, 2025 · Completed: Feb 10, 2030
1 condition
2 sponsors
3 locations
NCT07039929
Study to Assess the Safety, Tolerability, and Pharmacokinetics of INCB000631 When Administered Orally to Healthy Adult Participants
PHASE1
Recruiting
48 participants
Started: Jul 28, 2025 · Completed: Jan 3, 2026
1 condition
1 sponsor
1 location
NCT06859424
A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
PHASE2
Recruiting
358 participants
Started: Jul 25, 2025 · Completed: Jun 30, 2028
11 conditions
3 sponsors
3 locations
NCT07018635
A Study to Assess the Effect of Itraconazole, Rifampin, and Acid-Reducing Agents on INCB161734 Pharmacokinetics When Administered Orally in Healthy Participants
PHASE1
Recruiting
72 participants
Started: Jul 16, 2025 · Completed: Oct 29, 2025
1 condition
1 sponsor
1 location
NCT06873789
A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors
PHASE1/PHASE2
Active, not recruiting
9 participants
Started: Jun 30, 2025 · Completed: Oct 30, 2028
3 conditions
1 sponsor
9 locations
NCT06934980
A Study to Evaluate Microneedle-based Collection of Dermal Interstitial Skin Fluid in Healthy Participants and Atopic Dermatitis Participants
N/A
Recruiting
20 participants
Started: Jun 27, 2025 · Completed: Nov 21, 2025
2 conditions
1 sponsor
1 location
NCT06843408
A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD
PHASE1/PHASE2
Recruiting
30 participants
Started: Jun 25, 2025 · Completed: Dec 31, 2027
1 condition
1 sponsor
9 locations
NCT06959225
Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)
PHASE3
Recruiting
400 participants
Started: Jun 23, 2025 · Completed: Jul 11, 2027
1 condition
1 sponsor
108 locations
NCT06832618
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
PHASE3
Recruiting
240 participants
Started: Jun 17, 2025 · Completed: May 18, 2028
1 condition
1 sponsor
96 locations
NCT06958211
Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)
PHASE3
Recruiting
450 participants
Started: Jun 12, 2025 · Completed: Jul 11, 2027
1 condition
1 sponsor
111 locations
NCT06821542
A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy
PHASE3
Active, not recruiting
9 participants
Started: Jun 4, 2025 · Completed: Nov 30, 2032
1 condition
1 sponsor
130 locations
NCT06936566
MAGIC Ruxolitinib for aGVHD
PHASE2
Recruiting
98 participants
Started: May 14, 2025 · Completed: Apr 14, 2028
3 conditions
3 sponsors
11 locations
NCT06663722
Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease
PHASE2
Recruiting
49 participants
Started: May 5, 2025 · Completed: May 5, 2030
2 conditions
2 sponsors
1 location
NCT06615050
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)
PHASE3
Recruiting
572 participants
Started: Apr 2, 2025 · Completed: Jan 17, 2031
1 condition
5 sponsors
26 locations
NCT06818812
A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
PHASE1
Active, not recruiting
30 participants
Started: Mar 27, 2025 · Completed: Mar 27, 2027
1 condition
1 sponsor
9 locations
NCT06653777
Efficacy of Pemigatinib in Patients With Solid Tumors Characterized by an Alteration of the Gene FGFR in Tumor Cells
PHASE2
Recruiting
40 participants
Started: Mar 27, 2025 · Completed: Jun 30, 2028
1 condition
3 sponsors
6 locations
NCT06760156
Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell Lym
PHASE2
Recruiting
28 participants
Started: Mar 19, 2025 · Completed: Jan 31, 2028
1 condition
2 sponsors
1 location
NCT06855498
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
PHASE3
Recruiting
600 participants
Started: Feb 28, 2025 · Completed: Feb 28, 2028
1 condition
1 sponsor
342 locations
NCT06300528
Pemigatinib in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphomas
PHASE2
Recruiting
27 participants
Started: Feb 4, 2025 · Completed: Dec 31, 2030
1 condition
2 sponsors
1 location
NCT06548360
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo
PHASE3
Recruiting
180 participants
Started: Jan 24, 2025 · Completed: Mar 13, 2027
1 condition
1 sponsor
98 locations
NCT06585774
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
PHASE3
Recruiting
240 participants
Started: Jan 21, 2025 · Completed: Mar 31, 2030
1 condition
1 sponsor
95 locations
NCT06773195
A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis
PHASE1/PHASE2
Recruiting
37 participants
Started: Jan 7, 2025 · Completed: Jan 31, 2028
1 condition
3 sponsors
9 locations
NCT06660355
Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy
PHASE2
Recruiting
120 participants
Started: Dec 23, 2024 · Completed: Dec 31, 2028
1 condition
2 sponsors
1 location
NCT06649201
Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation
N/A
Recruiting
40 participants
Started: Dec 19, 2024 · Completed: Feb 15, 2027
2 conditions
2 sponsors
1 location
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