Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

RecruitingOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

December 19, 2024

Primary Completion Date

February 15, 2026

Study Completion Date

February 15, 2027

Conditions
Graft Vs Host DiseaseVulvovaginal Signs and Symptoms
Interventions
OTHER

Vulvovaginal Symptom Questionnaire

Participants will undergo assessment of vulvovaginal symptoms via the vulvovaginal questionnaire once pre-transplant, six months, and develop months post-transplant.

DIAGNOSTIC_TEST

Vaginal Microbiome Evaluation

A vaginal microbiome evaluation will be performed via vaginal exam by a gynecologist with collection of vaginal samples once pre-transplant, six months, and twelve months post-transplant.

Trial Locations (1)

44195

RECRUITING

Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Incyte Corporation

INDUSTRY

lead

Case Comprehensive Cancer Center

OTHER