Clinical Research
Total Trials
72
As Lead Sponsor
29
As Collaborator
43
Total Enrollment
3,774
NCT00216060
Risedronate to Prevent Skeletal Related Events in Patients With Metastatic Prostate Cancer Commencing Hormonal Therapy
Phase: Phase 3
Role: Collaborator
Start: Oct 31, 2003
Completion: Mar 31, 2008
NCT00216021
Capecitabine and Oxaliplatin in Treating Patients With Metastatic Breast Cancer
Phase: Phase 2
Role: Lead Sponsor
Start: Mar 31, 2004
Completion: Jun 30, 2007
NCT00216073
Capecitabine, Oxaliplatin and Trastuzumab in Treating Patients With HER2 Positive Metastatic Breast Cancer
Completion: Oct 31, 2006
NCT00216138
Docetaxel and Capecitabine for First Line Treatment of Metastatic Squamous Cell Carcinoma of the Head & Neck
Completion: Sep 30, 2007
NCT00216047
PTK787 + Trastuzumab for HER2 Overexpressing Metastatic Breast Cancer
Phase: Phase 1/2
Start: Jan 31, 2005
Completion: Aug 31, 2006
NCT00216216
Pemetrexed in Patients With Chemosensitive and Chemoresistant Relapsed Small Cell Lung Cancer
Completion: Oct 31, 2005
NCT00216164
Rituximab and Gemcitabine for Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Start: Apr 30, 2005
Completion: Mar 31, 2007
NCT00216151
Zoledronic Acid in the Management of Patients With Asymptomatic/Early Stage Multiple Myeloma
Start: Jun 30, 2005
NCT00235235
A Correlative Study for Predicting Response and Toxicity in Patients Receiving Chemotherapy for Breast Cancer
Phase: N/A
Start: Sep 30, 2005
Completion: Dec 31, 2010
NCT00234494
Cisplatin, Gemcitabine and Bevacizumab in Combination for Metastatic Transitional Cell Cancer
Start: Nov 30, 2005
Completion: Dec 31, 2008
NCT00317200
A Study of Paclitaxel Plus Bevacizumab in Patients With Chemosensitive Relapsed Small Cell Lung Cancer
Start: Apr 30, 2006
Completion: Nov 30, 2007
NCT00367601
Erlotinib + Bevacizumab for PS 2 Chemotherapy Naïve Non-Small Cell Lung Cancer
Start: Aug 31, 2006
NCT00472589
A Biological Sample Collection Protocol of Women With and Without Breast Cancer
Start: May 31, 2007
Completion: Aug 31, 2008
NCT00522665
Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer
Start: Aug 31, 2007
Completion: Feb 28, 2015
NCT00537173
Predicting Response and Toxicity in Patients Receiving Paclitaxel and Avastin for Breast Cancer
Start: Sep 30, 2007
Completion: Aug 31, 2009
NCT00526799
Sorafenib + Topotecan for Platinum-Resistant Recurrent Ovarian Cancer
Completion: Aug 31, 2010
NCT00632541
A Phase II Study of Bevacizumab + Sorafenib in Metastatic Breast Cancer
Start: Oct 31, 2007
Completion: Mar 31, 2009
NCT01085552
Bioequivalence of a Single Subcutaneous Dose of Epoetin Beta in Healthy Japanese and Caucasian Male Subjects
Phase: Phase 1
Start: Nov 30, 2007
Completion: Oct 31, 2008
NCT00572572
Aprepitant + a 5HT3 + Dexamethasone in Patients With Germ Cell Tumors
Start: Dec 31, 2007
Completion: Feb 28, 2011
NCT00613626
Cisplatin + Etoposide +/- Concurrent ZD6474 in Previously Untreated Extensive Stage Small Cell Lung Cancer
Start: Jan 31, 2008
Completion: Aug 31, 2015
NCT00608140
Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure
Start: Mar 31, 2008
Completion: Mar 31, 2010
NCT00706641
Neoadjuvant Dasatinib and Radical Cystectomy for Transitional Cell Carcinoma of the Bladder
Start: Jun 30, 2008
Completion: Dec 31, 2012
NCT00730353
Sutent + Taxol for Advanced Esophageal Cancer
Start: Aug 31, 2008
NCT00773474
Lonafarnib in Metastatic Breast Cancer
Start: Oct 31, 2008
Completion: Nov 30, 2010
NCT00732303
Pemetrexed and Radiation for Poor-Risk Stage III Non-Small Cell Lung Cancer
Start: Jan 31, 2009
NCT00859339
Neoadjuvant Cisplatin, Gemcitabine, Sunitinib Malate + Radical Cystectomy for TCC
Start: Mar 31, 2009
Completion: Apr 30, 2011
NCT00890955
Amrubicin + Cyclophosphamide in Advanced Solid Organ Malignancies
Completion: Jul 31, 2010
NCT01232881
Predicting Response and Toxicity in Patients Receiving Lonafarnib for Breast Cancer
Start: Aug 31, 2009
NCT01034631
BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma
Start: Jan 31, 2010
Completion: Dec 31, 2016
NCT01074970
PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations
Start: Feb 28, 2010
Completion: Dec 15, 2018
NCT01596803
Effects Antioxidants Supplementation on Muscular Function Patients Facioscapulohumeral Dystrophy (FSHD)
Start: May 1, 2010
Completion: Jun 1, 2012
NCT01071928
Second-Line Docetaxel + ASA404 for Advanced Urothelial Carcinoma
Start: Jun 30, 2010
Completion: Jun 30, 2010
NCT01177683
Bendamustine in Combination With Bortezomib and Pegylated Liposomal Doxorubicin for Multiple Myeloma
Start: Jul 31, 2010
Completion: Dec 31, 2017
NCT01186458
Fludarabine, Velcade and Rituximab for Relapsed or Refractory Follicular Non-Hodgkin Lymphoma
Start: Oct 31, 2010
Completion: Oct 31, 2013
NCT01215136
First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma
Start: Dec 31, 2010
Completion: Apr 24, 2018
NCT01485874
Doxorubicin + BIBF 1120 in Patients for Ovarian Cancer
Start: Nov 30, 2011
Completion: Dec 31, 2015
NCT01524991
First-Line Gemcitabine, Cisplatin + Ipilimumab for Metastatic Urothelial Carcinoma
Start: Jan 31, 2012
Completion: Dec 31, 2018
NCT01624493
BNC105P Combination Study in Partially Platinum Sensitive Ovarian Cancer Patients
Start: Oct 31, 2012
Completion: Oct 31, 2014
NCT01681433
OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific Antigen Progression While Receiving Abiraterone
Start: Dec 31, 2012
Completion: Jun 21, 2017
NCT01736917
Fosaprepitant + 5HT3 Receptor Antagonists + Dexamethasone in Germ Cell Tumors
Start: Jan 31, 2013
Completion: Jun 30, 2015
NCT01732107
Dovitinib in BCG Refractory Urothelial Carcinoma With FGFR3 Mutations or Over-expression
Start: Mar 31, 2013
Completion: Mar 6, 2017
NCT01780545
Phase 2 Study of Docetaxel +/- OGX-427 in Patients With Relapsed or Refractory Metastatic Bladder Cancer
Start: Apr 30, 2013
Completion: Oct 31, 2017
NCT02101385
Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer
Start: Apr 3, 2014
Completion: Sep 9, 2022
NCT02343952
Consolidation Pembrolizumab Following Chemoradiation in Patients With Inoperable/Unresectable Stage III NSCLC
Start: Mar 9, 2015
Completion: Jan 1, 2021
NCT02365766
Neoadjuvant Pembrolizumab in Combination With Gemcitabine Therapy in Cis-eligible/Ineligible UC Subjects
Start: May 27, 2015
Completion: Feb 23, 2024
NCT02375672
Study of Pembrolizumab in Combination With Chemotherapy for Patients With Advanced Colorectal Cancer
Start: May 28, 2015
Completion: Oct 8, 2020
NCT02382406
Carboplatin/Nab-Paclitaxel and Pembrolizumab in NSCLC
Start: Jun 4, 2015
Completion: Apr 14, 2022
NCT02500121
Testing the PD-1 Inhibitor Pembrolizumab as Maintenance Therapy After Initial Chemotherapy in Metastatic Bladder Cancer
Start: Nov 11, 2015
NCT02499952
Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors
Start: Jan 31, 2016
Completion: Jan 13, 2017
NCT02500901
Enzalutamide and Niraparib in the Treatment of Metastatic Castrate-Resistant Prostate Cancer (CRPC)
Start: Mar 31, 2016
Completion: May 10, 2016
NCT02581059
Efficacy of Ginseng for Patients on Regorafenib
Start: Apr 30, 2016
Completion: Jun 22, 2018
NCT02582749
Androgen Deprivation Therapy +/- Radium-223 Dichloride in Metastatic Prostate Cancer With Bone Metastases
Completion: Sep 14, 2017
NCT02581215
Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer
Start: Sep 11, 2016
Completion: Jan 27, 2022
NCT02586610
Trial of Chemoradiation and Pembrolizumab in Patients With Rectal Cancer
Start: Oct 31, 2016
Completion: Dec 31, 2020
NCT03041181
Single Agent Chemotherapy +/- Nivolumab in Patients With Advanced Squamous or Non-squamous NSCLC With Primary Resistance to Prior PD-1 or PDL-1 Inhibitor
Start: Jan 27, 2017
Completion: May 23, 2019
NCT03099564
Pembrolizumab Plus Y90 Radioembolization in HCC Subjects
Phase: Early Phase 1
Start: Mar 28, 2017
Completion: Jun 30, 2023
NCT03117309
Study of Front Line Therapy With Nivolumab and Salvage Nivolumab + Ipilimumab in Patients With Advanced Renal Cell Carcinoma
Start: Apr 24, 2017
Completion: Jan 23, 2025
NCT03035630
Sunitinib Followed by Avelumab or the Reverse for Metastatic Renal Cell Carcinoma
Start: May 23, 2017
NCT02982720
Evaluating Combination Immunotherapy for Advanced Cholangiocarcinoma With Pembrolizumab and PEG-Intron
Start: Jul 5, 2017
Completion: Feb 9, 2018
NCT02643043
UC-GENOME: Urothelial Cancer-GENOmic Analysis to iMprove Patient Outcomes and rEsearch
Start: Jul 26, 2017
Completion: Sep 13, 2023
NCT02549209
Pembro/Carbo/Taxol in Endometrial Cancer
Start: Aug 22, 2017
Completion: Feb 10, 2022
NCT03241186
Ipilimumab and Nivolumab as Adjuvant Treatment of Mucosal Melanoma
Start: Sep 12, 2017
Completion: Sep 30, 2023
NCT03272217
Atezolizumab With Bevacizumab in Previously Untreated Metastatic/Unresectable Urothelial Cancer
Start: Sep 13, 2017
Completion: Mar 17, 2022
NCT03317158
Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder
Start: Nov 21, 2017
Completion: Dec 31, 2026
NCT03396471
Study of Pembrolizumab and Concurrent Radiation in Patients With Previously Treated Carcinoma of Unknown Primary
Start: Feb 1, 2018
Completion: Mar 2, 2023
NCT03451331
Gemcitabine + Carboplatin + Nivolumab Versus Gemcitabine + Oxaliplatin + Nivolumab in Cisplatin-ineligible Patients With Metastatic Urothelial Cancer
Start: May 10, 2018
Completion: Jul 28, 2023
NCT03547999
A Trial of Perioperative CV301 Vaccination in Combination With Nivolumab and Systemic Chemotherapy for Metastatic CRC
Start: Jun 26, 2018
Completion: Mar 13, 2024
NCT03400254
"Gedatolisib, Hydroxychloroquine or the Combination for Prevention of Recurrent Breast Cancer (GLACIER)"
Start: Feb 26, 2019
Completion: Nov 12, 2019
NCT03971409
Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer
Start: Jul 8, 2019
Completion: Jun 30, 2026
NCT04848337
Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer
Start: May 25, 2021
Completion: Dec 31, 2025
NCT05520099
Observational Basket Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform
Start: Jun 26, 2023
Completion: Jan 31, 2027
NCT05956041
Pembrolizumab and Mogamulizumab in Advanced-stage, Relapsed/Refractory Cutaneous T-cell Lymphomas
Start: Dec 6, 2023
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