NCT01596803 - Effects Antioxidants Supplementation on Muscular Function Patients Facioscapulohumeral Dystrophy (FSHD) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 1, 2010

Primary Completion Date

February 20, 2012

Study Completion Date

June 1, 2012

Conditions

Facioscapulohumeral Muscular Dystrophy

Interventions

PROCEDURE

Taking of blood

Taking venous blood samples to analyse oxidant stress

DIETARY_SUPPLEMENT

needle biopsy of the vastus lateralis muscle

T0 needle biopsy of the vastus lateralis muscle (analysis of oxidative stress and inflammatory markers)During 17 weeks supplementation by Vit E, C , Zn Se After 17 weeks: veinous blood samples and needle biopsy

DIETARY_SUPPLEMENT

Vit C Vit E Zn Se

T0 venous blood samples and needle biopsy of the vastus lateralis muscle During 17 weeks vit E 400mg/d, Se 200µg/d, Vit C 500mg/day, Zn 25 mg/d After the supplementation of 17 weeks:venous blood samples and needle biopsy of the vastus lateralis muscle

DIETARY_SUPPLEMENT

Placebo Vit E Placebo Vit C Zn Se

venous blood samples and needle biopsy

Trial Locations (1)

34294

Montpellier University Hospital- Saint Eloi Hospital, Montpellier