Aprepitant + a 5HT3 + Dexamethasone in Patients With Germ Cell Tumors

PHASE3CompletedINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

December 31, 2007

Primary Completion Date

December 31, 2010

Study Completion Date

February 28, 2011

Conditions
Germ Cell Tumors
Interventions
DRUG

Aprepitant

Subjects will be randomized to receive aprepitant 125mg PO day 3 then 80mg on days 4-7 on either cycle 1 or cycle 2.

DRUG

Placebo

Subjects will be randomized to receive placebo on days 3-7 on either cycle 1 or cycle 2.

Trial Locations (6)

19104

University of Pennsylvania, Philadelphia

46202

Indiana University Simon Cancer Center, Indianapolis

47303

Medical Consultants, P.C., Muncie

53226

Froedtert/Medical College of Wisconsin, Milwaukee

63110

Siteman Cancer Center, St Louis

97213

Providence Portland Medical Center, Portland

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Hoosier Cancer Research Network

OTHER