Study of Pembrolizumab and Concurrent Radiation in Patients With Previously Treated Carcinoma of Unknown Primary

PHASE2TerminatedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

February 1, 2018

Primary Completion Date

August 12, 2021

Study Completion Date

March 2, 2023

Conditions
Carcinoma, Unspecified Site
Interventions
DRUG

Pembrolizumab

200mg IV at day -21, then day 1 of each 21-day cycle for a maximum of 24 continuous months of Pembrolizumab (35 cycles) from Cycle 1 Day 1 (C1D1) can be administered.

RADIATION

External Beam Radiation Therapy

20-30 Gy over five fractions for up to two cycles.

Trial Locations (2)

55905

Mayo Clinic, Rochester

77030

MD Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Hoosier Cancer Research Network

OTHER