Dovitinib in BCG Refractory Urothelial Carcinoma With FGFR3 Mutations or Over-expression

PHASE2TerminatedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

March 31, 2013

Primary Completion Date

March 6, 2017

Study Completion Date

March 6, 2017

Conditions
Bladder Cancer
Interventions
DRUG

Dovitinib

Dovitinib will be administered 500mg orally in a 5 days on, 2 days off dosing schedule. Day 12 assessments are intended to be performed on the last dosing day of the 2nd week in cycle 1 and cycle 2 and day 26 assessments are intended to be performed on the last dosing day of the 4th week in cycle 1 and cycle 2.

Trial Locations (3)

19046

Fox Chase Cancer Center Extramural Research Program, Rockledge

21231

Johns Hopkins University: Sidney Kimmel Comprehensive Cancer Center, Baltimore

46202

Indiana University Melvin and Bren Simon Cancer Center, Indianapolis

All Listed Sponsors
collaborator

Novartis Pharmaceuticals

INDUSTRY

collaborator

Hoosier Cancer Research Network

OTHER

lead

Noah Hahn, M.D.

OTHER