Clinical Trials for Ono Pharmaceutical

Explore 50 clinical trials worldwide

Showing 1-50 of 50 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: Ono Pharmaceutical

Clinical Trials (50)

NCT07169708
A Retrospective Observational Study of Nivolumab in Combination With Chemotherapy as Neoadjuvant Therapy for Resectable NSCLC Patients: Real-World Experience in Taiwan (NEOREAL)
N/ANot yet recruiting
100 participants
Started: Jan 31, 2026 · Completed: Dec 31, 2026
1 condition2 sponsors0 locations
NCT07104032
Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)
PHASE3Not yet recruiting
132 participants
Started: Nov 30, 2025 · Completed: Dec 31, 2029
1 condition2 sponsors0 locations
NCT07198087
A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants
PHASE1Recruiting
32 participants
Started: Oct 1, 2025 · Completed: Dec 31, 2026
1 condition1 sponsor2 locations
NCT06936943
ONO-4538 Study in Patients With Richter's Transformation
PHASE2Recruiting
14 participants
Started: Sep 30, 2025 · Completed: Jul 31, 2030
1 condition1 sponsor8 locations
NCT06948448
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
PHASE2Not yet recruiting
144 participants
Started: Jul 31, 2025 · Completed: Oct 1, 2028
1 condition1 sponsor0 locations
NCT06803823
A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia
PHASE2Recruiting
90 participants
Started: May 1, 2025 · Completed: Mar 31, 2027
1 condition1 sponsor25 locations
NCT06881836
A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease
PHASE2Recruiting
240 participants
Started: Apr 24, 2025 · Completed: Aug 31, 2026
1 condition1 sponsor50 locations
NCT06816108
A Study of ONO-7428 in Participants With Unresectable Advanced or Recurrent Solid Tumors
PHASE1Recruiting
60 participants
Started: Apr 21, 2025 · Completed: Jul 31, 2029
2 conditions1 sponsor3 locations
NCT06752603
A Clinical Study of ONO-1110 in Patients With Hunner Type Interstitial Cystitis
PHASE2Recruiting
50 participants
Started: Apr 2, 2025 · Completed: Aug 31, 2026
1 condition1 sponsor18 locations
NCT06752590
A Clinical Study of ONO-1110 in Patients With Fibromyalgia
PHASE2Recruiting
160 participants
Started: Mar 26, 2025 · Completed: Sep 30, 2026
1 condition1 sponsor27 locations
NCT06708416
A Study of ONO-1110 in Patients With Postherpetic Neuralgia
PHASE2Recruiting
140 participants
Started: Feb 12, 2025 · Completed: Aug 31, 2026
1 condition1 sponsor28 locations
NCT06805565
A Study of ONO-1110 in Patients With Social Anxiety Disorder
PHASE2Recruiting
100 participants
Started: Jan 16, 2025 · Completed: Oct 31, 2026
1 condition1 sponsor1 location
NCT06792136
A Study of ONO-1110 in Patients With Major Depressive Disorder
PHASE2Recruiting
100 participants
Started: Jan 16, 2025 · Completed: Aug 31, 2026
1 condition1 sponsor1 location
NCT06714370
Real-World Evidence of Effectiveness and Safety of Tirabrutinib in Patients with Relapsed or Refractory Primary Central Nervous System Lymphoma in Taiwan: a Nationwide Study
N/ANot yet recruiting
35 participants
Started: Dec 31, 2024 · Completed: Dec 31, 2026
1 condition1 sponsor0 locations
NCT06622226
A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
PHASE1Active, not recruiting
24 participants
Started: Nov 27, 2024 · Completed: Dec 31, 2029
1 condition1 sponsor6 locations
NCT06622941
Study to ONO-4538 in Patients With Rhabdoid Tumor
PHASE2Recruiting
23 participants
Started: Nov 25, 2024 · Completed: Mar 31, 2030
1 condition1 sponsor3 locations
NCT06541665
Phase I Study Evaluating Tolerability, Safety, Pharmacokinetics, and Efficacy of Combined ONO-4059 and R-MPV Therapy for PCNSL
PHASE1Active, not recruiting
20 participants
Started: May 17, 2024 · Completed: Aug 31, 2028
1 condition1 sponsor44 locations
NCT06548217
A Phase I Study of ONO-4538HSC in Subjects With Advanced or Metastatic Solid Tumors
PHASE1Active, not recruiting
31 participants
Started: May 7, 2024 · Completed: Feb 29, 2028
1 condition1 sponsor8 locations
NCT06256328
A Study to Investigate the Efficacy and Safety of ONO-4578 in Combination With Nivolumab and Chemotherapy in Chemotherapy-naïve Participants With HER2-negative Unresectable Advanced or Recurrent Gastric Cancer (Including Esophagogastric Junction Cancer)
PHASE2Active, not recruiting
210 participants
Started: Dec 6, 2023 · Completed: Jul 31, 2027
1 condition1 sponsor63 locations
NCT06532331
A PhaseⅠStudy of ONO-7475 in Combination With ONO-4538 and Gemcitabine Plus Nab-paclitaxel (GnP), the Standard of Care, and ONO-7475 in Combination With GnP in Patients With Pancreatic Cancer
PHASE1Active, not recruiting
87 participants
Started: Dec 6, 2023 · Completed: Mar 31, 2028
1 condition1 sponsor9 locations
NCT06940791
Tirabrutinib Maintenance Versus Placebo in Patients With Primary CNS Lymphoma in Complete Remission (JCOG2104)
PHASE2Recruiting
92 participants
Started: Oct 6, 2023 · Completed: Feb 28, 2030
1 condition4 sponsors1 location
NCT06547528
A Phase I Study to Investigate the Tolerability and Safety of ONO-4685 Given as Monotherapy in T Cell Lymphoma and CLL/SLL
PHASE1Recruiting
108 participants
Started: Oct 1, 2023 · Completed: Apr 30, 2029
1 condition1 sponsor14 locations
NCT05923866
A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy
PHASE2Active, not recruiting
92 participants
Started: Sep 22, 2023 · Completed: Aug 31, 2025
1 condition1 sponsor35 locations
NCT06159478
Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume)
PHASE2Recruiting
32 participants
Started: Mar 29, 2023 · Completed: Sep 30, 2027
2 conditions2 sponsors6 locations
NCT05515406
A Study to Investigate the Safety, Tolerability, PK, PD, and Efficacy of ONO-7018 in Patients With R/R NHL or CLL
PHASE1Active, not recruiting
108 participants
Started: Feb 13, 2023 · Completed: Dec 31, 2027
2 conditions1 sponsor10 locations
NCT05779592
A Study to Evaluate Nivolumab in Japanese Participants With Muscle-invasive Urothelial Carcinoma
N/AActive, not recruiting
400 participants
Started: Nov 23, 2022 · Completed: Sep 30, 2027
1 condition2 sponsors1 location
NCT06590896
Safety of Cenobamate in Japanese Subjects With Partial Onset Seizures
PHASE2Recruiting
100 participants
Started: Nov 4, 2022 · Completed: Jan 31, 2027
1 condition1 sponsor29 locations
NCT06696716
ONO-4059 Study in Patients With Steroid-resistant Pemphigus
PHASE3Recruiting
34 participants
Started: Aug 15, 2022 · Completed: Mar 31, 2029
2 conditions1 sponsor20 locations
NCT06579573
ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures.
PHASE3Recruiting
15 participants
Started: Jul 12, 2022 · Completed: Jan 31, 2027
1 condition1 sponsor25 locations
NCT05334719
A Study of the Effectiveness and Safety of Nivolumab Plus Chemotherapy in Participants With Untreated Advanced/Recurrent Gastric Cancer
N/AActive, not recruiting
500 participants
Started: Jun 29, 2022 · Completed: Sep 30, 2026
1 condition2 sponsors1 location
NCT04947319
Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)
PHASE2Recruiting
112 participants
Started: Dec 29, 2021 · Completed: Mar 31, 2027
2 conditions1 sponsor45 locations
NCT05079282
Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma
PHASE1Recruiting
217 participants
Started: Dec 10, 2021 · Completed: Mar 31, 2027
1 condition1 sponsor17 locations
NCT06570031
ONO-4578-06:Phase I Study of ONO-4578 and Letrozole Plus CDK4 /6 Inhibitors in Breast Cancer
PHASE1Active, not recruiting
46 participants
Started: Nov 9, 2021 · Completed: Apr 30, 2026
4 conditions1 sponsor13 locations
NCT05144854
A Study to Evaluate the Efficacy and Safety of ONO-4538 in Combination With Ipilimumab and Chemotherapy in Chemotherapy-naïve Participants With HER2-negative Unresectable Advanced or Recurrent Gastric Cancer (Including Esophagogastric Junction Cancer)
PHASE3Active, not recruiting
626 participants
Started: Nov 5, 2021 · Completed: May 31, 2027
1 condition1 sponsor57 locations
NCT06540261
The Study of ONO-7913, ONO-4538 and the Standard of Care as First-line Treatment in Patients Colorectal Cancer
PHASE1Active, not recruiting
65 participants
Started: Sep 23, 2021 · Completed: Dec 31, 2027
1 condition1 sponsor17 locations
NCT06525246
Study of ONO-7475 in Combination With Osimertinib in EGFR Gene Mutation-positive Non-small Cell Lung Cancer
PHASE1Active, not recruiting
78 participants
Started: Aug 6, 2021 · Completed: Apr 30, 2026
5 conditions1 sponsor13 locations
NCT06532344
An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, the Standard of Care, as First-line Treatment in Patients With Metastatic Pancreatic Cancer
PHASE1Active, not recruiting
32 participants
Started: Jul 30, 2021 · Completed: Dec 31, 2026
1 condition1 sponsor9 locations
NCT06542731
An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Docetaxel and Ramucirumab as Second-line Therapy in Patients With Advanced or Recurrent Non-small Cell Lung Cancer
PHASE1Active, not recruiting
42 participants
Started: Jun 1, 2021 · Completed: Dec 31, 2026
1 condition1 sponsor13 locations
NCT06547385
Study of ONO-4578 and XELOX/FOLFOX Plus Bevacizumab in Colorectal Cancer
PHASE1Active, not recruiting
40 participants
Started: Jan 13, 2021 · Completed: Oct 31, 2027
1 condition1 sponsor9 locations
NCT04607421
A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer
PHASE3Active, not recruiting
831 participants
Started: Dec 21, 2020 · Completed: Dec 28, 2027
1 condition4 sponsors268 locations
NCT04566380
ONO-4538 Phase II Rollover Study (ONO-4538-98)
PHASE2Recruiting
59 participants
Started: Sep 10, 2020 · Completed: Dec 31, 2026
1 condition1 sponsor38 locations
NCT04078295
A Study of E7389 Liposomal Formulation (E7389-LF) Plus Nivolumab in Participants With Solid Tumor
PHASE1/PHASE2Active, not recruiting
125 participants
Started: Sep 5, 2019 · Completed: Mar 31, 2026
1 condition2 sponsors19 locations
NCT04008030
A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)
PHASE3Active, not recruiting
839 participants
Started: Aug 5, 2019 · Completed: Jun 10, 2026
1 condition2 sponsors157 locations
NCT05696548
Nivolumab Plus Lenvatinib Against Anaplastic Thyroid Cancer (NAVIGATION)
PHASE2Active, not recruiting
51 participants
Started: Jul 2, 2019 · Completed: Dec 31, 2026
1 condition2 sponsors10 locations
NCT03661320
A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Therapy After Surgery With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle Invasive Bladder Cancer
PHASE3Active, not recruiting
855 participants
Started: Nov 6, 2018 · Completed: Dec 30, 2027
2 conditions2 sponsors172 locations
NCT03383458
A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation
PHASE3Active, not recruiting
545 participants
Started: Apr 18, 2018 · Completed: Dec 16, 2025
2 conditions2 sponsors184 locations
NCT03141177
A Study of Nivolumab Combined With Cabozantinib Compared to Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma
PHASE3Active, not recruiting
701 participants
Started: Jul 23, 2017 · Completed: Jan 16, 2026
1 condition3 sponsors135 locations
NCT03155061
Study of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors
PHASE1Active, not recruiting
183 participants
Started: Apr 19, 2017 · Completed: Mar 31, 2027
1 condition1 sponsor22 locations
NCT03036098
Study of Nivolumab in Combination With Ipilimumab or Standard of Care Chemotherapy Compared to the Standard of Care Chemotherapy Alone in Treatment of Participants With Untreated Inoperable or Metastatic Urothelial Cancer
PHASE3Active, not recruiting
1,314 participants
Started: Mar 24, 2017 · Completed: Nov 24, 2025
1 condition2 sponsors174 locations
NCT02632409
An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer
PHASE3Active, not recruiting
709 participants
Started: Mar 22, 2016 · Completed: May 27, 2027
1 condition2 sponsors188 locations