Clinical Trials Directory

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat

EBD RCT Trial in Living Donor Liver Transplantation

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma

First-in-Human Study of the GDF-15 Neutralizing Antibody Visugromab (CTL-002) in Patients With Advanced Cancer (GDFATHER)

ROX Index for the Timing of Intubation in Nasal High Flow

Dacomitinib in Lung Cancer With Uncommon EGFR Mutations

Endoscopic Cyclophotocoagulation in Normal Tension Glaucoma

The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study

Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

Extracellular RNA Biomarkers of Myotonic Dystrophy

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

Upper-limb Active Function and Botulinum Toxin a

Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa

Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy

NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors

Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

Reduced Occupational Sitting in Type 2 Diabetes Using mHealth (Mobile Health)

Investigating Whether Acute Elevation of Fatty Acid Levels Alters Cerebral Glucose Transport and Metabolism

A Neuro-Technological Intervention for Adolescents With GAD

A Trial of Durvalumab (MEDI 4736) in Combination With Extended Neoadjuvant Regimens in Rectal Cancer

Triac Trial II in MCT8 Deficiency Patients

Does Chronic Obstructive Lung Disease Influence the Cognitive Function

Study of the Safety and Effectiveness of HIFU Combined With REGOTORI for Metastatic Colorectal Cancer

Prediction of Neoadjuvant Chemotherapy Response Using Contrast-Enhanced Ultrasound in Patients With Locally Advanced Breast Cancer

Interest of Medical Hypnosis in Anxious Patients Treated by Radiotherapy

Ketogenic Diet & Functional Recovery in Moderate to Severe Traumatic Brain Injury

Mechanisms for Activation of Beige Adipose Tissue in Humans

Dd-cfDNA and Treg in Prediction of Kidney Transplant Acute Rejection

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

Highly Suppressive Treg in Delayed and Slow Graft Function After Kidney Transplantation

Evaluation of Neuroinflammation FNOS PET/CT in HIV (+) and (-) Subjects With OUD and Healthy Controls

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study

Maintenance With Olaparib or Selumetinib + Durvaluma for m-PDAC Guided by BRCAness and KRAS Status.

Early Caries Lesion Management Observational Study

BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy

Artificial Intelligence for Screening of Multiple Corneal Diseases

Discovering Urinary Protein Biomarkers for Hepatocellular Carcinoma in Chronic Hepatitis B Population

RCT of EF Family Training for P ADHD

Evolocumab in STEMI

A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Creating Peace: Community-based Youth Violence Prevention to Address Racism and Discrimination

A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

Tofacitinib in Adult Patients With Moderate to Severe Ulcerative Colitis