NCT04427826View on ClinicalTrials.gov

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

December 8, 2020

Primary Completion Date

June 30, 2026

Study Completion Date

January 31, 2027

Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG

Morphine hydrochloride

A single open-label injection of morphine (T0) at the dose closest to that defined by the model (estimation by Bayesian method) from among the following 4 doses: 0.02; 0.04; 0.07 and 0.1mg/kg will be adminestred to the patients.

Trial Locations (1)

38043

RECRUITING

Emergency Department of Grenoble Alpes University Hospital, Grenoble

All Listed Sponsors
lead

University Hospital, Grenoble

OTHER