Encapsulated Cell Therapy
Total Trials
28
As Lead Sponsor
23
As Collaborator
5
Total Enrollment
4,057
NCT00321997
A Clinical Trial to Explore Safety and Efficacy of Different Doses of Pegaptanib Sodium, Compared to Sham, in Patients With Wet AMD.
Phase: Phase 2/3
Role: Lead Sponsor
Start: May 31, 2001
Completion: Oct 31, 2007
NCT00021736
Phase II/III Study of Anti-VEGF in Neovascular AMD
Start: Jul 31, 2001
Completion: Jul 31, 2002
NCT00040313
Pegaptanib Sodium Compared to Sham Injection in Patients With DME Involving the Center of the Macula
Phase: Phase 2
Start: Oct 31, 2002
Completion: Feb 28, 2005
NCT00215670
Study of the Safety, Tolerability and Pharmacokinetics of 1 Mg/Eye and 3 Mg/Eye Pegaptanib Sodium in Patients With Exudative Age-Related Macular Degeneration (AMD)
Start: Nov 30, 2002
Completion: May 31, 2006
NCT00087763
Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD)
Start: Mar 31, 2004
NCT00088283
Pegaptanib Sodium Compared to Sham Injection in Patients With Recent Vision Loss Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO)
Start: May 31, 2004
Completion: Not specified
NCT00088192
Intravitreous Pegaptanib Sodium Injection in Patients With Exudative Age-Related Macular Degeneration (AMD)
Phase: N/A
Start: Jul 31, 2004
NCT00134667
Macugen (Pegaptanib Sodium) Alone, Versus Macugen in Combination With PDT (Photodynamic Therapy) With Visudyne (Verteporfin) in Patients With Age-Related Macular Degeneration (AMD)
Phase: Phase 4
Start: Mar 31, 2005
Completion: Oct 31, 2008
NCT00295828
A Pilot Study for the Treatment of Iris Neovascularization With Macugen
Phase: Phase 1
Role: Collaborator
Start: Jan 31, 2006
Completion: Sep 30, 2008
NCT00406107
Evaluation of Macugen Treatment of Macular Edema Due to Branch Retinal Vein Occlusion
Completion: Apr 30, 2008
NCT00312351
A Clinical Trial to Explore the Safety and Efficacy of Three Different Doses of Pegaptanib Sodium in Patients With Wet Age-Related Macular Degeneration (AMD)
Start: Apr 30, 2006
Completion: Nov 30, 2006
NCT00354445
A Clinical Trial to Explore the Safety and Efficacy of Injections of Macugen When Given Every 6 Weeks in Subjects With AMD
Start: Jun 30, 2006
NCT00346983
Macugen to Prevent Worsening of Macular Edema Following Cataract Surgery in Diabetics
Phase: Phase 1/2
Completion: May 31, 2007
NCT00358423
The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular Edema
Start: Jul 31, 2006
Completion: Feb 28, 2007
NCT00447954
A Study of an Encapsulated Cell Technology (ECT) Implant for Patients With Atrophic Macular Degeneration
Start: Jan 5, 2007
Completion: May 11, 2009
NCT00447993
A Study of Encapsulated Cell Technology (ECT) Implant for Patients With Late Stage Retinitis Pigmentosa
Start: Jan 8, 2007
Completion: May 26, 2009
NCT00447980
A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa
Start: Jan 22, 2007
Completion: Apr 19, 2010
NCT01327911
Ciliary Neurotrophic Factor (CNTF) Safety Trial in Patients With Macular Telangiectasia (Mactel)
Start: May 31, 2011
Completion: Sep 30, 2016
NCT01530659
Retinal Imaging in CNTF -Releasing Encapsulated Cell Implant Treated Patients for Early-stage Retinitis Pigmentosa
Start: Jan 31, 2012
Completion: Jul 1, 2019
NCT01949324
A Phase 2 Multicenter Randomized Clinical Trial of CNTF for MacTel
Start: Apr 30, 2014
Completion: May 22, 2017
NCT02228304
Study of the Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology (ECT) for the Treatment of Recurrent Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)
Start: Sep 30, 2014
Completion: Apr 30, 2016
NCT03071965
Extension Study of NT-501 Ciliary Neurotrophic Factor (CNTF) Implant for Macular Telangiectasia (MacTel)
Start: May 12, 2017
Completion: May 11, 2021
NCT03316300
A Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2 - Protocol A
Phase: Phase 3
Start: Nov 24, 2017
Completion: Sep 23, 2022
NCT03319849
A Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2 - Protocol B
Start: Jan 22, 2018
NCT04729972
Safety Study to Evaluate Bilateral CNTF Implants in Subjects With MacTel Type 2
Start: Jul 21, 2021
Completion: Dec 8, 2022
NCT06397131
A Study to Determine the Safety and Efficacy of NT-501 With MHFM
Start: Mar 6, 2025
Completion: Jul 24, 2026
NCT06971939
Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants
Start: Aug 15, 2025
Completion: Aug 15, 2030
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