70
Participants
Start Date
May 12, 2017
Primary Completion Date
May 11, 2021
Study Completion Date
May 11, 2021
Ciliary neurotrophic factor (CNTF)
The investigational product is the NT-501 encapsulated cell system, which consists of cells encapsulated within a semi-permeable polymer membrane and supportive matrices. NT-501 contains NTC-201 cells that secrete recombinant human CNTF, which were derived from genetically modified NTC-200 cells.
Surgery
Surgery to implant device for NT-501
Surgery
Sham surgery
Sydney Eye Hospital, Sydney
Centre for Eye Research Australia, East Melbourne
Lions Eye Institute, Nedlands
NIH Clinical Center, Rockville
Emory University School of Medicine, Dept of Ophthalmology, Emory University Eye Center, Atlanta
University of Miami-Miller School of Medicine, Bascom Palmer Eye Institute, Miami
Retina Associates of Cleveland, Inc, Cleveland
University of Michigan, Kellogg Eye Center, Ann Arbor
University of Wisconsin-Madison, Department of Ophthalmology and Visual Sciences, Madison
Stein Eye Institute / David Geffen School of Medicine, Los Angeles
Massachusetts Eye and Ear Infirmary, Boston
Lead Sponsor
Neurotech Pharmaceuticals
INDUSTRY