NCT01949324 - A Phase 2 Multicenter Randomized Clinical Trial of CNTF for MacTel | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

April 30, 2014

Primary Completion Date

April 14, 2017

Study Completion Date

May 22, 2017

Conditions

Macular Telangiectasia Type 2

Interventions

BIOLOGICAL

Ciliary neurotrophic factor (CNTF)

Ciliary neurotrophic factor released from NT-501 encapsulated cell implant

PROCEDURE

Sham procedure

Sham surgery for Sham arm

DEVICE

NT-501 Implant

NT-501 encapsulated cell implant

PROCEDURE

NT-501 Implant procedure

Surgery to implant device for NT-501 encapsulated cell implant releasing human ciliary neurotrophic factor arm

Trial Locations (11)

National Eye Institute, Bethesda

Emory University, Atlanta

Bascom Palmer, Miami

Retina Associates of Cleveland, Inc., Beachwood

University of Michigan, Kellogg Eye Center, Ann Arbor

University of Wisconsin, Madison

Jules Stein Eye Institute, Los Angeles

Massachusetts Eye and Ear Infirmary, Retina Service, Boston

Save Sight Institute, Sydney

Centre for Eye Research Australia, East Melbourne

Lions Eye Institute, Nedlands