Antibody-Oligonucleotide Conjugates
Total Trials
10
As Lead Sponsor
9
As Collaborator
1
Total Enrollment
1,384
NCT04635891
Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)
Phase: N/A
Role: Collaborator
Start: Dec 15, 2020
Completion: Jan 31, 2028
NCT05027269
Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients
Phase: Phase 1/2
Role: Lead Sponsor
Start: Oct 28, 2021
Completion: Feb 14, 2023
NCT05479981
Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients
Phase: Phase 2
Start: Aug 4, 2022
Completion: Sep 10, 2025
NCT05670730
Study of AOC 1044 in Healthy Adult Volunteers and Participants With Duchenne Muscular Dystrophy (DMD) Mutations Amenable to Exon 44 Skipping
Start: Nov 9, 2022
Completion: Nov 25, 2024
NCT05747924
Phase 1/2 Study of AOC 1020 in Participants With Facioscapulohumeral Muscular Dystrophy (FSHD)
Start: Apr 4, 2023
Completion: Apr 30, 2027
NCT06244082
Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy Participants With Mutations Amenable to Exon44 Skipping
Start: Jan 22, 2024
Completion: Jul 31, 2027
NCT06411288
Global Study of Del-desiran for the Treatment of DM1
Phase: Phase 3
Start: May 30, 2024
Completion: Sep 30, 2026
NCT06547216
Phase 2 Open-label Extension Study of AOC 1020 in Participants with Facioscapulohumeral Muscular Dystrophy (FSHD)
Start: Jul 25, 2024
Completion: Apr 30, 2028
NCT07038200
A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD
Start: Jun 10, 2025
Completion: Jul 31, 2028
NCT07008469
Global Open-Label Extension Study of Del-desiran for the Treatment of DM1
Start: Jul 25, 2025
Completion: Oct 31, 2030
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