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Clinical Trials for Kura Oncology
Explore 12 clinical trials worldwide
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Showing 1-12 of 12 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Kura Oncology
Clinical Trials (12)
NCT06930352
Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy
PHASE2
Not yet recruiting
70 participants
Started: Jan 10, 2026 · Completed: Dec 31, 2027
1 condition
2 sponsors
1 location
NCT07007312
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
PHASE3
Recruiting
1,300 participants
Started: Sep 26, 2025 · Completed: Nov 30, 2031
1 condition
1 sponsor
2 locations
NCT06655246
A Study of Ziftomenib, an Oral Menin Inhibitor, in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
PHASE1
Recruiting
157 participants
Started: Mar 27, 2025 · Completed: Dec 31, 2028
6 conditions
1 sponsor
23 locations
NCT06376162
Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia
PHASE1
Recruiting
20 participants
Started: Mar 18, 2025 · Completed: Jan 31, 2027
3 conditions
2 sponsors
20 locations
NCT06448013
A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia
PHASE1
Recruiting
22 participants
Started: Mar 7, 2025 · Completed: Dec 31, 2030
1 condition
2 sponsors
1 location
NCT06397027
A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine in Pediatric Relapsed and Refractory Acute Leukemias
PHASE1
Recruiting
22 participants
Started: Dec 27, 2024 · Completed: Dec 31, 2030
2 conditions
2 sponsors
1 location
NCT06001788
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
PHASE1
Recruiting
171 participants
Started: Feb 22, 2024 · Completed: Aug 31, 2027
12 conditions
1 sponsor
43 locations
NCT05848687
TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II
PHASE1/PHASE2
Recruiting
90 participants
Started: Nov 3, 2023 · Completed: Dec 31, 2033
1 condition
5 sponsors
25 locations
NCT06026410
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
PHASE1
Recruiting
270 participants
Started: Oct 18, 2023 · Completed: Apr 30, 2027
6 conditions
2 sponsors
32 locations
NCT05735184
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
PHASE1
Recruiting
420 participants
Started: Jul 18, 2023 · Completed: Apr 30, 2030
10 conditions
1 sponsor
44 locations
NCT04997902
Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)
PHASE1/PHASE2
Active, not recruiting
40 participants
Started: Dec 7, 2021 · Completed: Dec 31, 2025
1 condition
1 sponsor
11 locations
NCT04067336
First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia
PHASE1/PHASE2
Recruiting
263 participants
Started: Sep 12, 2019 · Completed: Oct 16, 2028
7 conditions
1 sponsor
56 locations