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Clinical Trials for Iovance Biotherapeutics
Explore 17 clinical trials worldwide
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Showing 1-17 of 17 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Iovance Biotherapeutics
Clinical Trials (17)
NCT07192900
Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease
PHASE1
Not yet recruiting
10 participants
Started: Oct 31, 2025 · Completed: Oct 31, 2037
4 conditions
4 sponsors
1 location
NCT05639972
E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
PHASE1/PHASE2
Recruiting
15 participants
Started: Aug 11, 2025 · Completed: Oct 1, 2026
17 conditions
2 sponsors
2 locations
NCT06940739
A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel
PHASE1/PHASE2
Recruiting
42 participants
Started: Mar 11, 2025 · Completed: Jul 31, 2032
3 conditions
1 sponsor
2 locations
NCT06481592
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.
PHASE2
Recruiting
60 participants
Started: Oct 29, 2024 · Completed: Nov 30, 2029
1 condition
1 sponsor
10 locations
NCT06566092
Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants
PHASE1
Recruiting
40 participants
Started: Mar 28, 2024 · Completed: Jul 31, 2028
5 conditions
1 sponsor
5 locations
NCT06151847
Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma
PHASE2
Recruiting
12 participants
Started: Dec 21, 2023 · Completed: Nov 27, 2025
4 conditions
3 sponsors
1 location
NCT05727904
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
PHASE3
Recruiting
670 participants
Started: Mar 30, 2023 · Completed: Mar 1, 2030
3 conditions
1 sponsor
72 locations
NCT05686226
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
PHASE2
Recruiting
20 participants
Started: Mar 7, 2023 · Completed: Jan 1, 2027
21 conditions
3 sponsors
2 locations
NCT05640193
A Study of LN-144 in People With Metastatic Melanoma to the Brain
PHASE1
Active, not recruiting
10 participants
Started: Nov 25, 2022 · Completed: Nov 30, 2026
1 condition
3 sponsors
1 location
NCT05607095
A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma
PHASE1
Recruiting
20 participants
Started: Nov 1, 2022 · Completed: May 1, 2026
4 conditions
2 sponsors
2 locations
NCT05483491
KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer
PHASE1
Recruiting
30 participants
Started: Sep 26, 2022 · Completed: Dec 31, 2028
4 conditions
3 sponsors
2 locations
NCT05361174
A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
PHASE1/PHASE2
Recruiting
53 participants
Started: Jul 20, 2022 · Completed: Jun 30, 2027
4 conditions
1 sponsor
10 locations
NCT05176470
Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients
PHASE1
Active, not recruiting
2 participants
Started: Jul 1, 2022 · Completed: Dec 31, 2025
5 conditions
2 sponsors
1 location
NCT04614103
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
PHASE2
Recruiting
170 participants
Started: May 7, 2021 · Completed: Dec 31, 2031
1 condition
1 sponsor
64 locations
NCT03645928
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
PHASE2
Recruiting
245 participants
Started: May 7, 2019 · Completed: Aug 9, 2029
3 conditions
1 sponsor
45 locations
NCT03449108
LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas
PHASE2
Active, not recruiting
30 participants
Started: Apr 27, 2018 · Completed: Apr 30, 2027
16 conditions
3 sponsors
1 location
NCT01937468
Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease
PHASE1
Active, not recruiting
25 participants
Started: Nov 30, 2013 · Completed: Dec 31, 2025
3 conditions
4 sponsors
2 locations