Clinical Trials for Iovance Biotherapeutics

Explore 17 clinical trials worldwide

Showing 1-17 of 17 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: Iovance Biotherapeutics

Clinical Trials (17)

NCT07192900
Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease
PHASE1Not yet recruiting
10 participants
Started: Oct 31, 2025 · Completed: Oct 31, 2037
4 conditions4 sponsors1 location
NCT05639972
E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
PHASE1/PHASE2Recruiting
15 participants
Started: Aug 11, 2025 · Completed: Oct 1, 2026
17 conditions2 sponsors2 locations
NCT06940739
A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel
PHASE1/PHASE2Recruiting
42 participants
Started: Mar 11, 2025 · Completed: Jul 31, 2032
3 conditions1 sponsor2 locations
NCT06481592
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.
PHASE2Recruiting
60 participants
Started: Oct 29, 2024 · Completed: Nov 30, 2029
1 condition1 sponsor10 locations
NCT06566092
Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants
PHASE1Recruiting
40 participants
Started: Mar 28, 2024 · Completed: Jul 31, 2028
5 conditions1 sponsor5 locations
NCT06151847
Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma
PHASE2Recruiting
12 participants
Started: Dec 21, 2023 · Completed: Nov 27, 2025
4 conditions3 sponsors1 location
NCT05727904
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
PHASE3Recruiting
670 participants
Started: Mar 30, 2023 · Completed: Mar 1, 2030
3 conditions1 sponsor72 locations
NCT05686226
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
PHASE2Recruiting
20 participants
Started: Mar 7, 2023 · Completed: Jan 1, 2027
21 conditions3 sponsors2 locations
NCT05640193
A Study of LN-144 in People With Metastatic Melanoma to the Brain
PHASE1Active, not recruiting
10 participants
Started: Nov 25, 2022 · Completed: Nov 30, 2026
1 condition3 sponsors1 location
NCT05607095
A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma
PHASE1Recruiting
20 participants
Started: Nov 1, 2022 · Completed: May 1, 2026
4 conditions2 sponsors2 locations
NCT05483491
KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer
PHASE1Recruiting
30 participants
Started: Sep 26, 2022 · Completed: Dec 31, 2028
4 conditions3 sponsors2 locations
NCT05361174
A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
PHASE1/PHASE2Recruiting
53 participants
Started: Jul 20, 2022 · Completed: Jun 30, 2027
4 conditions1 sponsor10 locations
NCT05176470
Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients
PHASE1Active, not recruiting
2 participants
Started: Jul 1, 2022 · Completed: Dec 31, 2025
5 conditions2 sponsors1 location
NCT04614103
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
PHASE2Recruiting
170 participants
Started: May 7, 2021 · Completed: Dec 31, 2031
1 condition1 sponsor64 locations
NCT03645928
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
PHASE2Recruiting
245 participants
Started: May 7, 2019 · Completed: Aug 9, 2029
3 conditions1 sponsor45 locations
NCT03449108
LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas
PHASE2Active, not recruiting
30 participants
Started: Apr 27, 2018 · Completed: Apr 30, 2027
16 conditions3 sponsors1 location
NCT01937468
Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease
PHASE1Active, not recruiting
25 participants
Started: Nov 30, 2013 · Completed: Dec 31, 2025
3 conditions4 sponsors2 locations