A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 29, 2024

Primary Completion Date

May 31, 2028

Study Completion Date

November 30, 2029

Conditions
Endometrial Cancer
Interventions
BIOLOGICAL

Lifileucel

A tumor sample is resected from each patient and cultured ex vivo to expand the population of tumor infiltrating lymphocytes. After lymphodepleting chemotherapy including cyclophosphamide and fludarabine, participant is infused with lifileucel, followed by IL-2.

Trial Locations (10)

14203

RECRUITING

Roswell Park Cancer Institute, Buffalo

15524

RECRUITING

Allegheny Health, Pittsburgh

32806

RECRUITING

Orlando Health, Orlando

33612

RECRUITING

H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa

40202

RECRUITING

UofL Health - Brown Cancer Center, Louisville

48201

RECRUITING

Barbara Ann Karmanos Cancer Hospital, Detroit

57105

RECRUITING

Avera Medical Group Oncology, Sioux Falls

73117

RECRUITING

University of Oklahoma, Oklahoma City

77030

RECRUITING

MD Anderson Cancer Center - U of Texas, Houston

90007

RECRUITING

University of Southern California, Los Angeles

Sponsors
All Listed Sponsors
lead

Iovance Biotherapeutics, Inc.

INDUSTRY