Clinical Trials for Acerta Pharma

Explore 22 clinical trials worldwide

Showing 1-22 of 22 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: Acerta Pharma

Clinical Trials (22)

NCT06757647
Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
PHASE2Recruiting
61 participants
Started: May 27, 2025 · Completed: Dec 31, 2027
1 condition3 sponsors1 location
NCT05495464
"A Pilot Window-3 Study of Acalabrutinib Plus Rituximab Followed by Brexucabtagene Autoleucel Therapy in Patients With Previously Untreated High-risk Mantle Cell Lymphoma"
EARLY_PHASE1Active, not recruiting
22 participants
Started: Nov 18, 2022 · Completed: Mar 31, 2027
2 conditions3 sponsors1 location
NCT04529772
A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)
PHASE3Active, not recruiting
611 participants
Started: Oct 8, 2020 · Completed: Feb 1, 2027
1 condition2 sponsors255 locations
NCT03899337
A Trial of CHOP-R Therapy, With or Without Acalabrutinib, in Patients With Newly Diagnosed Richter's Syndrome
PHASE2Recruiting
105 participants
Started: Jul 23, 2019 · Completed: May 31, 2027
1 condition3 sponsors16 locations
NCT03836261
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
PHASE3Active, not recruiting
984 participants
Started: Feb 25, 2019 · Completed: Jan 31, 2027
1 condition2 sponsors170 locations
NCT03328273
A Study of AZD6738 and Acalabrutinib in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
PHASE1Active, not recruiting
12 participants
Started: Jan 31, 2018 · Completed: Aug 26, 2026
1 condition1 sponsor11 locations
NCT02972840
A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL
PHASE3Active, not recruiting
635 participants
Started: Apr 5, 2017 · Completed: Oct 28, 2025
1 condition2 sponsors228 locations
NCT02970318
A Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL
PHASE3Active, not recruiting
310 participants
Started: Feb 2, 2017 · Completed: Oct 1, 2027
1 condition1 sponsor157 locations
NCT02717624
A Study of Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL
PHASE1Active, not recruiting
72 participants
Started: Apr 20, 2016 · Completed: Aug 20, 2027
1 condition2 sponsors15 locations
NCT02717611
A Study of ACP-196 (Acalabrutinib) in Subjects With Relapsed/Refractory CLL and Intolerant of Ibrutinib Therapy
PHASE2Active, not recruiting
60 participants
Started: Mar 8, 2016 · Completed: Sep 6, 2026
1 condition1 sponsor23 locations
NCT02586857
A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)
PHASE1/PHASE2Active, not recruiting
24 participants
Started: Jan 25, 2016 · Completed: Apr 1, 2026
1 condition1 sponsor7 locations
NCT02477696
Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Participants With High Risk Chronic Lymphocytic Leukemia (CLL)
PHASE3Active, not recruiting
533 participants
Started: Jul 28, 2015 · Completed: Jan 3, 2028
1 condition1 sponsor131 locations
NCT02475681
Acalabrutinib, Obinutuzumab and Chlorambucil in Treatment naïve CLL
PHASE3Active, not recruiting
535 participants
Started: Jun 26, 2015 · Completed: Sep 30, 2025
1 condition1 sponsor155 locations
NCT02213926
An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma
PHASE2Active, not recruiting
124 participants
Started: Mar 2, 2015 · Completed: Sep 6, 2026
1 condition1 sponsor58 locations
NCT02362035
ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies
PHASE1/PHASE2Active, not recruiting
161 participants
Started: Feb 20, 2015 · Completed: Apr 1, 2026
13 conditions2 sponsors19 locations
NCT02337829
Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL
PHASE2Active, not recruiting
48 participants
Started: Jan 12, 2015 · Completed: Apr 1, 2026
2 conditions2 sponsors1 location
NCT02180711
Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma
PHASE1/PHASE2Active, not recruiting
113 participants
Started: Dec 29, 2014 · Completed: Dec 29, 2028
1 condition2 sponsors32 locations
NCT02296918
Acalabrutinib in Combination With Anti-CD20 and Venetoclax in Relapsed/Refractory or Untreated CLL/SLL/PLL
PHASE1Active, not recruiting
69 participants
Started: Dec 22, 2014 · Completed: Sep 6, 2027
3 conditions1 sponsor1 location
NCT02328014
Acalabrutinib (ACP-196) in Combination With ACP-319, for Treatment of B-Cell Malignancies
PHASE1/PHASE2Active, not recruiting
40 participants
Started: Dec 20, 2014 · Completed: Apr 1, 2026
3 conditions2 sponsors7 locations
NCT02180724
An Open-label, Phase 2 Study of ACP-196 in Subjects With Waldenström Macroglobulinemia
PHASE2Active, not recruiting
107 participants
Started: Sep 11, 2014 · Completed: Dec 31, 2026
1 condition1 sponsor38 locations
NCT02157324
Acalabrutinib in Combination With ACP-319, for Treatment of Chronic Lymphocytic Leukemia
PHASE1Active, not recruiting
12 participants
Started: Aug 18, 2014 · Completed: Apr 1, 2026
1 condition1 sponsor3 locations
NCT02029443
ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia, Richter's Syndrome or Prolymphocytic Leukemia
PHASE1/PHASE2Active, not recruiting
306 participants
Started: Jan 30, 2014 · Completed: Sep 6, 2027
4 conditions1 sponsor12 locations