T Cell Receptor Fragment Therapies
Total Trials
18
As Lead Sponsor
14
As Collaborator
4
Total Enrollment
4,541
NCT01211262
Study to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant Melanoma
Phase: Phase 1
Role: Lead Sponsor
Start: Sep 28, 2010
Completion: Feb 16, 2017
NCT02535078
Phase 1b/2 Study of the Combination of IMCgp100 With Durvalumab and/or Tremelimumab in Advanced Cutaneous Melanoma
Phase: Phase 1/2
Start: Nov 30, 2015
Completion: Sep 6, 2023
NCT02570308
A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma
Start: Feb 29, 2016
Completion: Oct 17, 2022
NCT02889861
IMCgp100-401 Rollover Study
Phase: Phase 2
Start: Jan 11, 2017
Completion: Apr 22, 2019
NCT03070392
Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal Melanoma
Start: Oct 16, 2017
Completion: Dec 31, 2025
NCT03515551
Safety and Efficacy of IMCnyeso in Advanced NY-ESO-1 and/or LAGE-1A Positive Cancers
Start: Jun 15, 2018
Completion: May 10, 2021
NCT03973333
Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab
Start: May 17, 2019
Completion: Sep 25, 2023
NCT04262466
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors
Start: Feb 25, 2020
Completion: Aug 31, 2026
NCT05867056
Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection
Start: Aug 12, 2020
Completion: Dec 15, 2024
NCT05315258
Tebentafusp in Molecular Relapsed Disease (MRD) Melanoma
Role: Collaborator
Start: Jul 25, 2022
Completion: Jun 30, 2027
NCT05549297
Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)
Phase: Phase 3
Start: Dec 19, 2022
Completion: Jul 31, 2028
NCT06840119
Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers
Start: Jan 10, 2024
Completion: Nov 30, 2027
NCT06112314
IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)
Start: Jun 5, 2024
Completion: Oct 16, 2027
NCT07156136
Study of IMC-P115C in Advanced PRAME-Positive Cancers
Start: Nov 7, 2024
Completion: Aug 30, 2029
NCT06246149
Adjuvant Tebentafusp in High Risk Ocular Melanoma
Start: Nov 11, 2024
Completion: Nov 30, 2032
NCT06627244
Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma
Start: Feb 14, 2025
Completion: Feb 17, 2031
NCT06070012
Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma
Start: Mar 10, 2025
Completion: Mar 31, 2030
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