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Clinical Trials for PYC Therapeutics
Explore 7 clinical trials worldwide
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Showing 1-7 of 7 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: PYC Therapeutics
Clinical Trials (7)
NCT06970106
Safety of Single and Repeat Dose of PYC-001 Eye Injections in People With Autosomal Dominant Optic Atrophy
PHASE1/PHASE2
Recruiting
21 participants
Started: Sep 30, 2025 · Completed: Jan 1, 2027
4 conditions
1 sponsor
2 locations
NCT06852963
A Study of Two Doses of VP-001 Administered Intravitreally in Participants with Confirmed PRPF31 Mutation-Associated Retinal Dystrophy Previously Treated with VP001
PHASE1/PHASE2
Not yet recruiting
12 participants
Started: Jun 1, 2025 · Completed: Aug 1, 2027
5 conditions
1 sponsor
6 locations
NCT06714006
Phase 1 Study to Evaluate the Safety and Tolerability of Intravenously Administered PYC-003
PHASE1
Recruiting
56 participants
Started: Apr 7, 2025 · Completed: Jan 31, 2026
1 condition
1 sponsor
6 locations
NCT06461286
SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)
PHASE1
Recruiting
18 participants
Started: Oct 31, 2024 · Completed: Aug 31, 2025
4 conditions
1 sponsor
2 locations
NCT06455826
MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)
PHASE1
Recruiting
12 participants
Started: Jun 13, 2024 · Completed: Nov 30, 2025
5 conditions
1 sponsor
5 locations
NCT05902962
SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects
PHASE1
Active, not recruiting
20 participants
Started: Apr 20, 2023 · Completed: Aug 30, 2025
3 conditions
1 sponsor
6 locations
NCT05573984
Natural History of PRPF31 Mutation-Associated Retinal Dystrophy
N/A
Active, not recruiting
50 participants
Started: Jul 7, 2022 · Completed: Feb 28, 2026
5 conditions
1 sponsor
7 locations