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Clinical Trials for Apellis Pharmaceuticals
Explore 10 clinical trials worldwide
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Showing 1-10 of 10 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Apellis Pharmaceuticals
Clinical Trials (10)
NCT07213960
A Sequential Phase 2/3 Study of APL2 in Patients With Focal Segmental Glomerulosclerosis
PHASE2/PHASE3
Not yet recruiting
270 participants
Started: Dec 31, 2025 · Completed: Dec 31, 2029
1 condition
1 sponsor
2 locations
NCT07214740
Study to Evaluate a Pegcetacoplan (Syfovre®) Prefilled Syringe
PHASE3
Not yet recruiting
36 participants
Started: Oct 31, 2025 · Completed: Jan 31, 2026
1 condition
1 sponsor
0 locations
NCT07020832
A Phase 3 Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults at High Risk of Delayed Graft Function (DGF) Following Kidney Allograft Transplantation
PHASE3
Not yet recruiting
320 participants
Started: Sep 30, 2025 · Completed: Aug 31, 2028
3 conditions
1 sponsor
0 locations
NCT07215390
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio
PHASE2
Recruiting
240 participants
Started: Jun 23, 2025 · Completed: Nov 30, 2027
1 condition
1 sponsor
2 locations
NCT06161584
A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration
N/A
Recruiting
300 participants
Started: Sep 28, 2023 · Completed: Jun 30, 2028
1 condition
1 sponsor
34 locations
NCT05809531
An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis
PHASE3
Active, not recruiting
100 participants
Started: May 29, 2023 · Completed: Jul 31, 2027
12 conditions
1 sponsor
47 locations
NCT04572854
Study Assessing the Safety and Efficacy of Pegcetacoplan in Post-Transplant Recurrence of C3G or IC-MPGN
PHASE2
Active, not recruiting
13 participants
Started: Sep 7, 2021 · Completed: Jan 31, 2026
12 conditions
1 sponsor
25 locations
NCT04770545
An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMD
PHASE3
Active, not recruiting
1,200 participants
Started: Mar 4, 2021 · Completed: Sep 30, 2026
1 condition
1 sponsor
175 locations
NCT04901936
A Study of Pegcetacoplan in Pediatric Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)
PHASE2
Recruiting
12 participants
Started: Feb 4, 2021 · Completed: Dec 31, 2028
2 conditions
1 sponsor
12 locations
NCT03531255
Pegcetacoplan Long Term Safety and Efficacy Extension Study
PHASE3
Active, not recruiting
160 participants
Started: Aug 27, 2018 · Completed: Jun 30, 2025
1 condition
1 sponsor
62 locations