Genome Editing Therapies (CRISPR)
Total Trials
7
As Lead Sponsor
6
As Collaborator
1
Total Enrollment
418
NCT03396042
Natural History Study of CEP290-Related Retinal Degeneration
Phase: N/A
Role: Lead Sponsor
Start: Dec 17, 2017
Completion: May 6, 2022
NCT03872479
Single Ascending Dose Study in Participants With LCA10
Phase: Phase 1/2
Start: Sep 26, 2019
Completion: May 23, 2025
NCT04853576
A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)
Start: May 4, 2021
Completion: Aug 31, 2025
NCT05444894
EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT)
Start: Apr 29, 2022
Completion: Dec 31, 2025
NCT06752512
Remote Temperature Monitoring of Patients At Risk for Developing Fever
Role: Collaborator
Start: Aug 9, 2023
Completion: Jan 31, 2025
NCT06363760
A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301
Start: Jun 17, 2024
Completion: Aug 31, 2040
NCT06950190
Evaluating Cognitive Changes on Patients in Chemotherapy (ECCPC)
Phase: Phase 3
Start: Jun 9, 2025
Completion: Feb 20, 2027
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