Autologous Cell Therapy, Contract Cell Therapy Manufacturing
Total Trials
30
As Lead Sponsor
20
As Collaborator
10
Total Enrollment
5,226
NCT00005947
Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
Phase: Phase 3
Role: Lead Sponsor
Start: Nov 30, 1999
Completion: Sep 30, 2004
NCT01133704
Immunotherapy With APC8015 (Sipuleucel-T, Provenge) for Asymptomatic, Metastatic, Hormone-Refractory Prostate Cancer
Start: May 31, 2000
Completion: May 31, 2005
NCT00779402
PROvenge Treatment and Early Cancer Treatment
Start: Oct 31, 2001
Completion: May 31, 2015
NCT00065442
Provenge® (Sipuleucel-T) Active Cellular Immunotherapy Treatment of Metastatic Prostate Cancer After Failing Hormone Therapy
Start: Jul 31, 2003
Completion: Jan 31, 2009
NCT00849290
Immunotherapy For Men With Objective Disease Progression On Protocol D9902 Part B (NCT00065442)
Phase: Phase 2
Start: Apr 30, 2004
Completion: Apr 30, 2009
NCT00715104
Sipuleucel-T as Neoadjuvant Treatment in Prostate Cancer
Start: Jul 31, 2008
Completion: Dec 31, 2013
NCT00715078
To Evaluate Sipuleucel-T Manufactured With Different Concentrations of (PA2024) Antigen
Start: Oct 31, 2008
NCT00839631
Dose Escalation Study of EC D-3263 HCl in Advanced Solid Tumors
Phase: Phase 1
Start: Mar 31, 2009
Completion: Apr 30, 2012
NCT00901342
Open Label Study of Sipuleucel-T in Metastatic Prostate Cancer
Start: Oct 31, 2009
Completion: Jun 30, 2015
NCT01306890
A Registry of Sipuleucel-T Therapy in Men With Advanced Prostate Cancer
Phase: N/A
Start: Jan 27, 2011
Completion: Jan 17, 2017
NCT01353222
DN24-02 as Adjuvant Therapy in Subjects With High Risk HER2+ Urothelial Carcinoma
Start: Jun 30, 2011
Completion: Jul 31, 2015
NCT01431391
Sequencing of Sipuleucel-T and ADT in Men With Non-metastatic Prostate Cancer
Start: Sep 30, 2011
Completion: Dec 31, 2014
NCT01338012
Sipuleucel-T in Metastatic Castrate Resistant Prostate Cancer
Start: Dec 31, 2011
Completion: Apr 30, 2015
NCT01487863
Concurrent vs. Sequential Sipuleucel-T & Abiraterone Treatment in Men With Metastatic Castrate Resistant Prostate Cancer
Completion: Jun 30, 2016
NCT01981109
Positive Imaging Study for Distant Metastases in Patients With Castration-Resistant Prostate Cancer
Start: Jan 31, 2012
Completion: Jul 31, 2017
NCT01477749
Sipuleucel-T Manufacturing Demonstration Study
Start: Jun 30, 2012
Completion: Jun 30, 2014
NCT01727154
Immune Monitoring Protocol in Men With Prostate Cancer Enrolled in a Clinical Trial of Sipuleucel-T
Start: Oct 31, 2012
NCT01706458
Provenge With or Without pTVG-HP DNA Booster Vaccine in Prostate Cancer
Role: Collaborator
Start: May 20, 2013
Completion: Aug 13, 2020
NCT01833208
Radiation Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Receiving Sipuleucel-T
Start: Jul 3, 2013
Completion: Jan 23, 2021
NCT01981122
A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate Cancer
Start: Sep 30, 2013
Completion: Jun 30, 2017
NCT02042053
PET/MR Assessment of Sipuleucel T Treatment for Metastatic Castration Resistant Prostate Cancer
Start: Jan 31, 2014
Completion: Oct 31, 2015
NCT01804465
Sipuleucel-T With Immediate vs. Delayed Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Blockade for Prostate Cancer
Start: Apr 22, 2014
Completion: Aug 31, 2020
NCT02232230
A Multicenter Trial Enrolling Men With Advanced Prostate Cancer Who Are to Receive Combination Radiation and Sipuleucel-T
Start: Jun 30, 2014
Completion: Jun 5, 2018
NCT02463799
Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC
Start: Feb 22, 2016
Completion: Dec 12, 2019
NCT03024216
Clinical Study of Atezolizumab (Anti-PD-L1) and Sipuleucel-T in Patients With Asymptomatic or Minimally Symptomatic Metastatic Castrate Resistant Prostate Cancer
Start: Feb 6, 2017
Completion: Dec 31, 2020
NCT03686683
Open- Label Trial of Sipuleucel-T Administered to Active Surveillance Patients for Newly Diagnosed Prostate Cancer
Start: Oct 18, 2018
Completion: Mar 10, 2023
NCT05751941
Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate Cancer
Start: Feb 14, 2023
Completion: Dec 31, 2026
NCT06134232
Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T
Start: Oct 2, 2023
Completion: Jun 30, 2032
NCT05806814
Sipuleucel-T Based Autologous Cellular Immunotherapy for Advanced Prostate Cancer
Start: Nov 12, 2023
NCT06100705
Sipuleucel-T Combined with Bipolar Androgen Therapy in Men with MCRPC
Start: Dec 20, 2023
Completion: Mar 31, 2028
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