Sequencing of Sipuleucel-T and ADT in Men With Non-metastatic Prostate Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

September 30, 2011

Primary Completion Date

December 31, 2014

Study Completion Date

December 31, 2014

Conditions
Prostatic NeoplasmProstate CancerProstatic Adenocarcinoma
Interventions
BIOLOGICAL

sipuleucel-T

Sipuleucel-T is an autologous cellular product consisting of antigen presenting cells (APCs) activated with PA2024, a recombinant fusion protein composed of prostatic acid phosphatase (PAP), linked to granulocyte-macrophage colony-stimulating factor (GM-CSF).

DRUG

leuprolide acetate

45.0 mg depot injection, 2 doses 6 months apart

Trial Locations (14)

12206

NYOH Albany Cancer Center at Patroon Creek, Albany

12208

Community Care Physicians, PC, Albany

21287

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

29572

Grand Strand Urology, Myrtle Beach

35209

Urology Center of Alabama, Homewood

78229

Urology San Antonio Research, San Antonio

80211

The Urology Center of Colorado, Denver

89169

Comprehensive Cancer Centers of Nevada, Las Vegas

90033

Keck Hospital of USC, Los Angeles

LAC + USC Medical Center, Los Angeles

USC / Norris Comprehensive Cancer Center, Los Angeles

91914

University of California San Diego / Moores Cancer Center, La Jolla

98101

Virginia Mason Medical Center, Seattle

98109

Seattle Cancer Care Alliance, Seattle

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Dendreon

INDUSTRY

NCT01431391 - Sequencing of Sipuleucel-T and ADT in Men With Non-metastatic Prostate Cancer | Biotech Hunter | Biotech Hunter