127
Participants
Start Date
November 30, 1999
Primary Completion Date
September 30, 2004
Study Completion Date
September 30, 2004
sipuleucel-T
Autologous peripheral blood mononuclear cells, including antigen presenting cells, that have been activated in vitro with a recombinant fusion protein, PAP-GM-CSF. Treatment consist of 3 doses administered approximately 2 weeks apart.
Placebo
Approximately one-third of the autologous quiescent antigen presenting cells (APCs) prepared from a single leukapheresis procedure. A course of therapy consists of 3 complete doses given at approximately 2-week intervals.
St. Vincents Comprehensive Cancer Center, New York
NYU School of Medicine's Kaplan Comprehensive Cancer Center, New York
St. Luke's-Roosevelt Hospital, New York
New York Presbyterian Hospital - Cornell Campus, New York
Albert Einstein Comprehensive Cancer Center, The Bronx
New York Medical College, Valhalla
Center for Medical Oncology, Garden City
Albany Regional Cancer Center, Albany
University of Rochester Cancer Center, Rochester
Hematology/Oncology Associates of NE Pennsylvania, P.C., Scranton
Abington Hematology Oncology Associates, Incorporated, Abington
Bryn Mawr Urology, Bryn Mawr
Office of Guy Bernstein, M.D., Bryn Mawr
Saint Mary Regional Cancer Center, Langhorne
Devine Tidewater Urology, Norfolk
Office of Barry S. Berman, Orlando
AKSM Clinical Research Corporation, Columbus
Mayo Clinic Cancer Center, Rochester
American Oncology Resources, Dallas
Office of Glenn Tisman, Whittier
Sidney Kimmel Cancer Center, San Diego
Cancer and Blood Institute of the Desert, Rancho Mirage
Eisenhower Medical Center, Rancho Mirage
Loma Linda University Medical Center, Loma Linda
Seattle Cancer Care Alliance, Seattle
Hematology Oncology Northwest, P.C., Tacoma
Cancer Care Northwest, Spokane
Cancer Center and Beckman Research Institute, City of Hope, Duarte
UCSF Cancer Center and Cancer Research Institute, San Francisco
Hackensack University Medical Center, Hackensack
St. Barnabas Medical Center, Livingston
Morristown Memorial Hospital, Morristown
Earle A. Chiles Research Institute at Providence Portland Medical Center, Portland
North Penn Hospital, Lansdale
Lead Sponsor
Dendreon
INDUSTRY