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Clinical Trials for Merck
Explore 813 clinical trials worldwide
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Showing 1-50 of 813 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: Merck
Clinical Trials (813)
NCT05093972
Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)
PHASE1
Not yet recruiting
22 participants
Started: Apr 7, 2026 · Completed: Sep 10, 2026
1 condition
1 sponsor
0 locations
NCT07187778
Phase II Trial of Single Agent Belzutifan or Pembrolizumab Versus Combination as Neoadjuvant Therapy in Clear Cell Renal Cell Carcinoma (BLAZE)
PHASE2
Not yet recruiting
10 participants
Started: Feb 28, 2026 · Completed: Jul 19, 2029
1 condition
2 sponsors
1 location
NCT04901741
Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancer
PHASE2
Not yet recruiting
60 participants
Started: Jan 31, 2026 · Completed: Mar 31, 2029
1 condition
2 sponsors
0 locations
NCT07004413
Continuous or Intermittent Cetuximab Plus FOLFIRI as First-line Treatment in RAS/BRAF Wild-type mCRC Patients
PHASE3
Not yet recruiting
267 participants
Started: Jan 1, 2026 · Completed: Jan 1, 2031
1 condition
3 sponsors
1 location
NCT06271681
Evaluation of PCV21 Vaccination Among PPSV23-experienced, Immunocompromised Elderly Veterans
PHASE4
Not yet recruiting
45 participants
Started: Jan 1, 2026 · Completed: Jun 1, 2027
2 conditions
2 sponsors
0 locations
NCT06926062
Interpersonal Communication Training and Vaccination Workflow Training Alone and in Combination to Improve Communication and Recommendations About HPV Vaccination in Pharmacies, IMPACT HPV Trial
NA
Not yet recruiting
1,900 participants
Started: Dec 1, 2025 · Completed: Oct 1, 2027
1 condition
2 sponsors
2 locations
NCT06704308
Parents' HPV Stories
NA
Not yet recruiting
58 participants
Started: Nov 30, 2025 · Completed: Nov 30, 2026
1 condition
3 sponsors
1 location
NCT07217262
Proactive Costs of Care Study
NA
Not yet recruiting
24 participants
Started: Nov 30, 2025 · Completed: Apr 30, 2027
5 conditions
2 sponsors
1 location
NCT07209111
A Clinical Study of MK-1084 in People With Advanced Solid Tumors (MK-1084-014)
PHASE2
Not yet recruiting
150 participants
Started: Nov 24, 2025 · Completed: Apr 9, 2032
1 condition
1 sponsor
0 locations
NCT07199465
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
PHASE1
Recruiting
40 participants
Started: Nov 19, 2025 · Completed: May 19, 2028
1 condition
1 sponsor
1 location
NCT07216482
A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)
PHASE3
Not yet recruiting
975 participants
Started: Nov 19, 2025 · Completed: Mar 1, 2027
1 condition
1 sponsor
0 locations
NCT07216703
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)
PHASE3
Not yet recruiting
1,023 participants
Started: Nov 18, 2025 · Completed: Oct 29, 2031
1 condition
1 sponsor
0 locations
NCT07094893
Anti-EGFR Agents in Patients With Right-sided Advanced Colorectal Cancer With Wild-type RAS and AREG/EREG High Status
PHASE4
Not yet recruiting
280 participants
Started: Nov 15, 2025 · Completed: Mar 31, 2030
1 condition
2 sponsors
0 locations
NCT07218029
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
PHASE3
Not yet recruiting
815 participants
Started: Nov 14, 2025 · Completed: Dec 7, 2028
1 condition
1 sponsor
0 locations
NCT07089992
A Study of Pembrolizumab in People With Ultra-Rare Sarcomas
PHASE2
Not yet recruiting
32 participants
Started: Nov 11, 2025 · Completed: Aug 31, 2028
1 condition
2 sponsors
6 locations
NCT07219550
A Study of MK-1084 in Participants With Hepatic Impairment and Healthy Volunteers (MK-1084-017)
PHASE1
Not yet recruiting
58 participants
Started: Nov 3, 2025 · Completed: Apr 17, 2026
2 conditions
1 sponsor
0 locations
NCT06351345
129 Xenon Imaging in Patients Treated With Sotatercept
PHASE2
Not yet recruiting
14 participants
Started: Nov 1, 2025 · Completed: Aug 1, 2026
2 conditions
2 sponsors
1 location
NCT07110038
DEPECA-1 - A Phase II Study to Evaluate a First-line Systemic Therapy With Enfortumab Vedotin Plus Avelumab for Advanced and Metastatic Penile Carcinoma
PHASE2
Not yet recruiting
25 participants
Started: Oct 31, 2025 · Completed: Nov 30, 2030
1 condition
4 sponsors
1 location
NCT06876259
Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds
NA
Not yet recruiting
300 participants
Started: Oct 31, 2025 · Completed: Jul 1, 2026
2 conditions
2 sponsors
2 locations
NCT07194980
Nemtabrutinib and Lisocabtagene Maraleucel for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
PHASE2
Not yet recruiting
20 participants
Started: Oct 31, 2025 · Completed: Oct 20, 2029
2 conditions
2 sponsors
1 location
NCT07071623
A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)
PHASE3
Not yet recruiting
4,580 participants
Started: Oct 31, 2025 · Completed: Oct 18, 2027
2 conditions
1 sponsor
0 locations
NCT07199452
A Study of Rifabutin and MK-4646 in Healthy Participants (MK-4646-004)
PHASE1
Not yet recruiting
18 participants
Started: Oct 28, 2025 · Completed: Dec 27, 2025
1 condition
1 sponsor
0 locations
NCT06587243
"Facts Tell… and With Stories Sell? Combining Viewer-tailored Personal Human Papillomavirus (HPV) Narrative Video With HPV Vaccine Information Video to Improve HPV Vaccine Uptake"
NA
Not yet recruiting
1,100 participants
Started: Oct 16, 2025 · Completed: Jan 31, 2027
1 condition
2 sponsors
0 locations
NCT06655883
A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)
PHASE3
Not yet recruiting
300 participants
Started: Oct 13, 2025 · Completed: Jun 24, 2027
1 condition
1 sponsor
0 locations
NCT07166601
M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors
PHASE1
Recruiting
77 participants
Started: Oct 10, 2025 · Completed: Feb 23, 2029
1 condition
2 sponsors
5 locations
NCT07168915
A Study of V118E in Healthy Participants (V118E-003)
PHASE1
Recruiting
126 participants
Started: Oct 8, 2025 · Completed: Apr 8, 2027
1 condition
1 sponsor
1 location
NCT07176390
A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)
PHASE2
Recruiting
182 participants
Started: Oct 8, 2025 · Completed: Sep 3, 2029
1 condition
1 sponsor
4 locations
NCT07190248
A Clinical Study of MK-1084 and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)
PHASE3
Recruiting
675 participants
Started: Oct 8, 2025 · Completed: Aug 6, 2032
1 condition
1 sponsor
2 locations
NCT06899126
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
PHASE3
Recruiting
686 participants
Started: Oct 7, 2025 · Completed: Jul 5, 2032
1 condition
2 sponsors
26 locations
NCT07140484
Sotatercept in Pulmonary Arterial Hypertension
PHASE4
Recruiting
27 participants
Started: Oct 6, 2025 · Completed: Jan 1, 2030
1 condition
3 sponsors
1 location
NCT07135453
Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines
PHASE4
Not yet recruiting
105 participants
Started: Sep 30, 2025 · Completed: Aug 31, 2026
2 conditions
2 sponsors
1 location
NCT07015853
ASTRAEA: ReinvigorAting ReSponse To ImmunotheRApy in MEtAstatic TNBC With Combination Myeloid Inhibition and Radiation
PHASE2
Not yet recruiting
34 participants
Started: Sep 30, 2025 · Completed: Dec 31, 2032
2 conditions
3 sponsors
1 location
NCT07101055
Pharmacokinetics of Oral Letermovir in Adults With End-Stage Kidney Disease With or Without Haemodialysis
PHASE1
Not yet recruiting
20 participants
Started: Sep 30, 2025 · Completed: Dec 31, 2027
1 condition
3 sponsors
0 locations
NCT06822543
A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer)
PHASE2
Recruiting
46 participants
Started: Sep 30, 2025 · Completed: Nov 1, 2028
3 conditions
3 sponsors
1 location
NCT05992480
REVIVE (Response to the Ebola Virus Vaccine)
PHASE4
Not yet recruiting
40 participants
Started: Sep 30, 2025 · Completed: May 31, 2026
1 condition
3 sponsors
1 location
NCT07133633
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
PHASE2
Recruiting
315 participants
Started: Sep 26, 2025 · Completed: Feb 5, 2030
1 condition
1 sponsor
3 locations
NCT07086079
A Study of Doravirine/Islatravir in Healthy Lactating Females (MK-8591A-061)
PHASE1
Recruiting
12 participants
Started: Sep 26, 2025 · Completed: Jun 1, 2026
1 condition
1 sponsor
1 location
NCT07200570
Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy
NA
Not yet recruiting
1,800 participants
Started: Sep 26, 2025 · Completed: May 31, 2026
1 condition
2 sponsors
0 locations
NCT07089784
Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)
PHASE1
Recruiting
64 participants
Started: Sep 22, 2025 · Completed: Jan 12, 2026
1 condition
1 sponsor
8 locations
NCT07025551
A Clinical Study of MK-8527 in Participants With Mild and Moderate Hepatic Impairment (MK-8527-015)
PHASE1
Recruiting
18 participants
Started: Sep 19, 2025 · Completed: Jan 7, 2026
2 conditions
1 sponsor
1 location
NCT06890403
Can Stories Encourage the Elderly to Vaccinate? Combining Viewer-tailored Personal Narrative Videos With Informational Videos to Improve Vaccine Uptake Among Older Adults
NA
Recruiting
6,000 participants
Started: Sep 16, 2025 · Completed: Jan 31, 2027
1 condition
2 sponsors
1 location
NCT07082439
Pembrolizumab and Odetiglucan in Liver Predominant Metastatic Colorectal Adenocarcinoma
PHASE2
Recruiting
27 participants
Started: Sep 10, 2025 · Completed: Sep 30, 2029
1 condition
2 sponsors
1 location
NCT07058077
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
PHASE2/PHASE3
Recruiting
153 participants
Started: Aug 21, 2025 · Completed: Jan 24, 2037
1 condition
1 sponsor
2 locations
NCT07049939
A Study of Bomedemstat (MK-3543) in Participants With Mild or Moderate Hepatic Impairment (MK-3543-023)
PHASE1
Recruiting
24 participants
Started: Aug 20, 2025 · Completed: Mar 16, 2026
1 condition
1 sponsor
3 locations
NCT07063238
A Clinical Study of MK-8527 in Healthy Adult Participants (MK-8527-014)
PHASE1
Active, not recruiting
42 participants
Started: Aug 12, 2025 · Completed: Dec 15, 2025
1 condition
1 sponsor
1 location
NCT06979596
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
PHASE2
Recruiting
250 participants
Started: Aug 11, 2025 · Completed: Nov 4, 2027
1 condition
1 sponsor
11 locations
NCT07158918
ABL103 in Combination With Pembrolizumab, With or Without Taxane in Advanced or Metastatic Solid Tumors
PHASE1/PHASE2
Recruiting
65 participants
Started: Aug 6, 2025 · Completed: Dec 2, 2027
1 condition
2 sponsors
6 locations
NCT06799494
HPV Vaccine Reduced Dose
PHASE4
Recruiting
100 participants
Started: Aug 6, 2025 · Completed: Sep 30, 2028
1 condition
2 sponsors
1 location
NCT06624644
A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma
PHASE2/PHASE3
Recruiting
135 participants
Started: Aug 6, 2025 · Completed: Feb 28, 2031
4 conditions
2 sponsors
7 locations
NCT06960655
Improving Lipid Optimization Quality and Treatment Options in ASCVD
NA
Not yet recruiting
300 participants
Started: Aug 1, 2025 · Completed: Nov 1, 2026
2 conditions
2 sponsors
1 location
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