Clinical Trials for GlaxoSmithKline

Explore 254 clinical trials worldwide

Showing 1-50 of 254 trials

Active filters:Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruitingSponsor: GlaxoSmithKline

Clinical Trials (254)

NCT07104799
Momelotinib During and After HCT in Myelofibrosis
PHASE1Not yet recruiting
28 participants
Started: Jan 31, 2026 · Completed: Jan 31, 2030
2 conditions2 sponsors1 location
NCT07050732
Immunogenicity of RSVPreF3 Vaccine in Immunocompromised Persons
PHASE2Not yet recruiting
170 participants
Started: Dec 31, 2025 · Completed: Apr 30, 2028
1 condition2 sponsors1 location
NCT06412120
Study Evaluating Safety, Tolerability, and Metabolism of Niraparib
PHASE4Recruiting
70 participants
Started: Dec 1, 2025 · Completed: Oct 1, 2030
1 condition2 sponsors1 location
NCT07108270
A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Chinese Participants With Primary Advanced or Recurrent Endometrial Cancer (EC)
PHASE2Not yet recruiting
30 participants
Started: Nov 30, 2025 · Completed: Mar 31, 2030
1 condition1 sponsor0 locations
NCT07220109
A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus Given to Chinese Adults 18 to 59 Years of Age at Increased Risk of Respiratory Syncytial Virus Disease
PHASE3Not yet recruiting
750 participants
Started: Oct 31, 2025 · Completed: Dec 14, 2026
1 condition1 sponsor0 locations
NCT07098936
Momelotinib in VEXAS Syndrome
PHASE2Not yet recruiting
57 participants
Started: Oct 31, 2025 · Completed: Oct 31, 2028
2 conditions2 sponsors11 locations
NCT07218926
A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy
PHASE3Not yet recruiting
450 participants
Started: Oct 30, 2025 · Completed: Oct 28, 2030
1 condition1 sponsor0 locations
NCT07177339
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
PHASE3Not yet recruiting
1,196 participants
Started: Oct 20, 2025 · Completed: Dec 14, 2029
1 condition1 sponsor0 locations
NCT07204964
A Study to Evaluate the Immune Response and Safety of an Influenza Vaccine in Adults 18 Years of Age and Above
PHASE2Not yet recruiting
960 participants
Started: Oct 10, 2025 · Completed: Sep 18, 2026
1 condition1 sponsor0 locations
NCT07213609
A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
PHASE1/PHASE2Not yet recruiting
47 participants
Started: Oct 10, 2025 · Completed: Oct 27, 2028
1 condition1 sponsor0 locations
NCT07013851
Clinical Trial to Assess the Efficacy of Dostarlimab as Neoadjuvant Therapy in Patients With MMRd/MSI-H Stage II-III Endometrial Cancer
PHASE2Not yet recruiting
25 participants
Started: Oct 1, 2025 · Completed: Oct 1, 2029
1 condition2 sponsors1 location
NCT07115927
pReOperative Dostarlimab and Novel Therapies in EndOmetrial Cancer
PHASE2Not yet recruiting
40 participants
Started: Sep 30, 2025 · Completed: Jan 31, 2031
1 condition2 sponsors0 locations
NCT07201051
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
PHASE2Not yet recruiting
400 participants
Started: Sep 26, 2025 · Completed: Nov 8, 2027
1 condition1 sponsor0 locations
NCT07168356
A Study to Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease
PHASE1Recruiting
32 participants
Started: Sep 16, 2025 · Completed: Aug 18, 2026
1 condition1 sponsor1 location
NCT07121192
A Study to Assess the Immune Response and Safety of a Vaccine Against Influenza in Adults 18 Years of Age and Older
PHASE2Recruiting
770 participants
Started: Aug 25, 2025 · Completed: May 15, 2026
1 condition1 sponsor22 locations
NCT07105709
Open-label Extension Study in Participants With Early Alzheimer's Disease
PHASE2Recruiting
297 participants
Started: Aug 14, 2025 · Completed: Nov 24, 2028
1 condition2 sponsors5 locations
NCT07105722
A Trial to Evaluate the Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults 50 To 64 Years of Age
PHASE1Recruiting
120 participants
Started: Aug 12, 2025 · Completed: Jun 18, 2026
1 condition1 sponsor4 locations
NCT07099898
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)
PHASE3Recruiting
300 participants
Started: Aug 11, 2025 · Completed: Sep 11, 2028
1 condition1 sponsor14 locations
NCT07036159
A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months
PHASE2Recruiting
238 participants
Started: Aug 6, 2025 · Completed: Apr 23, 2027
1 condition1 sponsor2 locations
NCT07092865
A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant
PHASE2Recruiting
234 participants
Started: Aug 6, 2025 · Completed: Jul 16, 2027
1 condition1 sponsor2 locations
NCT07085702
A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of the GSK 4-component Strep A Vaccine With Aluminum Hydroxide (Alum) or AS37 in Healthy Young Adults
PHASE1Recruiting
108 participants
Started: Jul 31, 2025 · Completed: Nov 30, 2026
1 condition5 sponsors2 locations
NCT06897527
A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With Recurrent or Advanced Endometrial Cancer (EC)
PHASE4Not yet recruiting
100 participants
Started: Jul 15, 2025 · Completed: Jan 13, 2027
1 condition1 sponsor0 locations
NCT06995430
A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old)
PHASE3Recruiting
312 participants
Started: Jul 7, 2025 · Completed: Dec 10, 2025
1 condition1 sponsor3 locations
NCT07017803
Molecular Epidemiology, Strains Genotyping of Multi-drug Resistant Tuberculosis Circulating in Central Africa Region
N/ANot yet recruiting
460 participants
Started: Jul 1, 2025 · Completed: Jan 31, 2026
5 conditions4 sponsors0 locations
NCT06405230
Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Extracellular Vesicles (EVs), Patient-derived Organoid (PDOs)s and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)
PHASE1/PHASE2Not yet recruiting
40 participants
Started: Jun 27, 2025 · Completed: Jun 27, 2029
1 condition1 sponsor1 location
NCT06961214
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
PHASE3Recruiting
960 participants
Started: Jun 23, 2025 · Completed: Aug 21, 2029
1 condition1 sponsor1 location
NCT06959095
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)
PHASE3Recruiting
981 participants
Started: Jun 20, 2025 · Completed: Aug 20, 2029
1 condition1 sponsor15 locations
NCT06990880
A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer
PHASE1/PHASE2Recruiting
85 participants
Started: Jun 12, 2025 · Completed: Aug 9, 2028
1 condition1 sponsor5 locations
NCT06885034
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed
PHASE1/PHASE2Recruiting
320 participants
Started: Jun 11, 2025 · Completed: Jun 23, 2028
1 condition1 sponsor12 locations
NCT06847867
A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome
PHASE2Recruiting
80 participants
Started: Jun 5, 2025 · Completed: Mar 6, 2029
1 condition1 sponsor1 location
NCT06979323
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
PHASE3Recruiting
150 participants
Started: Jun 3, 2025 · Completed: Feb 11, 2028
1 condition1 sponsor1 location
NCT06979518
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GSK3862995B Administered as a Single Dose to Healthy Participants of Chinese, Japanese, and European Ancestry
PHASE1Not yet recruiting
30 participants
Started: May 20, 2025 · Completed: Apr 27, 2026
1 condition1 sponsor0 locations
NCT06806137
A Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Months After a First Dose at 12 to 15 Months of Age
PHASE3Recruiting
600 participants
Started: May 15, 2025 · Completed: Apr 2, 2027
1 condition1 sponsor1 location
NCT06747845
Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy
PHASE2Recruiting
68 participants
Started: May 7, 2025 · Completed: Jan 30, 2029
1 condition4 sponsors2 locations
NCT06911775
Eosinophil Subpopulations in Eosinophilic-associated Diseases
N/ANot yet recruiting
160 participants
Started: Apr 30, 2025 · Completed: Dec 31, 2026
3 conditions2 sponsors0 locations
NCT06887933
A Trial to Evaluate the Safety of Niraparib Tablets in Adult Female Participants With Advanced or Relapsed Epithelial Ovarian Cancer
PHASE4Not yet recruiting
67 participants
Started: Apr 22, 2025 · Completed: Jul 8, 2026
1 condition1 sponsor0 locations
NCT06855160
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age
PHASE3Recruiting
900 participants
Started: Apr 17, 2025 · Completed: Dec 24, 2026
1 condition1 sponsor6 locations
NCT06920043
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
PHASE2Recruiting
42 participants
Started: Apr 9, 2025 · Completed: Dec 31, 2027
1 condition2 sponsors35 locations
NCT06521567
A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
PHASE1/PHASE2Active, not recruiting
95 participants
Started: Mar 6, 2025 · Completed: Jan 2, 2032
12 conditions1 sponsor18 locations
NCT06796907
A Study of GSK5733584 in Combination With Anti-cancer Therapies for Advanced Solid Tumors
PHASE1/PHASE2Recruiting
392 participants
Started: Mar 4, 2025 · Completed: Apr 5, 2028
1 condition1 sponsor56 locations
NCT06702345
Clostridioides Difficile Controlled Human Infection Model
NANot yet recruiting
60 participants
Started: Mar 1, 2025 · Completed: Dec 31, 2026
3 conditions5 sponsors1 location
NCT06517875
Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis
PHASE2Recruiting
56 participants
Started: Feb 28, 2025 · Completed: Nov 13, 2026
2 conditions1 sponsor12 locations
NCT06757244
DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic Cancer
PHASE2Recruiting
35 participants
Started: Feb 18, 2025 · Completed: Feb 18, 2028
1 condition2 sponsors5 locations
NCT06567782
A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer
PHASE2Recruiting
120 participants
Started: Feb 17, 2025 · Completed: Jun 15, 2028
1 condition1 sponsor12 locations
NCT06748053
A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma
PHASE2Recruiting
300 participants
Started: Feb 10, 2025 · Completed: Jan 14, 2027
1 condition1 sponsor78 locations
NCT06740630
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age
PHASE3Recruiting
1,840 participants
Started: Jan 10, 2025 · Completed: May 13, 2027
1 condition1 sponsor5 locations
NCT06679101
A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)
PHASE3Recruiting
520 participants
Started: Dec 27, 2024 · Completed: Apr 6, 2032
2 conditions1 sponsor81 locations
NCT06763783
Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases
PHASE4Enrolling by invitation
240 participants
Started: Dec 17, 2024 · Completed: Jun 30, 2034
9 conditions2 sponsors1 location
NCT06710847
A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
PHASE1/PHASE2Recruiting
73 participants
Started: Dec 13, 2024 · Completed: Jun 16, 2028
5 conditions2 sponsors13 locations
NCT06716606
A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease
PHASE3Recruiting
225 participants
Started: Dec 12, 2024 · Completed: Jan 8, 2030
1 condition2 sponsors6 locations