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Clinical Trials for GlaxoSmithKline
Explore 254 clinical trials worldwide
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Showing 1-50 of 254 trials
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Status: Recruiting, Active, not recruiting, Enrolling by invitation, Not yet recruiting
Sponsor: GlaxoSmithKline
Clinical Trials (254)
NCT07104799
Momelotinib During and After HCT in Myelofibrosis
PHASE1
Not yet recruiting
28 participants
Started: Jan 31, 2026 · Completed: Jan 31, 2030
2 conditions
2 sponsors
1 location
NCT07050732
Immunogenicity of RSVPreF3 Vaccine in Immunocompromised Persons
PHASE2
Not yet recruiting
170 participants
Started: Dec 31, 2025 · Completed: Apr 30, 2028
1 condition
2 sponsors
1 location
NCT06412120
Study Evaluating Safety, Tolerability, and Metabolism of Niraparib
PHASE4
Recruiting
70 participants
Started: Dec 1, 2025 · Completed: Oct 1, 2030
1 condition
2 sponsors
1 location
NCT07108270
A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Chinese Participants With Primary Advanced or Recurrent Endometrial Cancer (EC)
PHASE2
Not yet recruiting
30 participants
Started: Nov 30, 2025 · Completed: Mar 31, 2030
1 condition
1 sponsor
0 locations
NCT07220109
A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus Given to Chinese Adults 18 to 59 Years of Age at Increased Risk of Respiratory Syncytial Virus Disease
PHASE3
Not yet recruiting
750 participants
Started: Oct 31, 2025 · Completed: Dec 14, 2026
1 condition
1 sponsor
0 locations
NCT07098936
Momelotinib in VEXAS Syndrome
PHASE2
Not yet recruiting
57 participants
Started: Oct 31, 2025 · Completed: Oct 31, 2028
2 conditions
2 sponsors
11 locations
NCT07218926
A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy
PHASE3
Not yet recruiting
450 participants
Started: Oct 30, 2025 · Completed: Oct 28, 2030
1 condition
1 sponsor
0 locations
NCT07177339
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
PHASE3
Not yet recruiting
1,196 participants
Started: Oct 20, 2025 · Completed: Dec 14, 2029
1 condition
1 sponsor
0 locations
NCT07204964
A Study to Evaluate the Immune Response and Safety of an Influenza Vaccine in Adults 18 Years of Age and Above
PHASE2
Not yet recruiting
960 participants
Started: Oct 10, 2025 · Completed: Sep 18, 2026
1 condition
1 sponsor
0 locations
NCT07213609
A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
PHASE1/PHASE2
Not yet recruiting
47 participants
Started: Oct 10, 2025 · Completed: Oct 27, 2028
1 condition
1 sponsor
0 locations
NCT07013851
Clinical Trial to Assess the Efficacy of Dostarlimab as Neoadjuvant Therapy in Patients With MMRd/MSI-H Stage II-III Endometrial Cancer
PHASE2
Not yet recruiting
25 participants
Started: Oct 1, 2025 · Completed: Oct 1, 2029
1 condition
2 sponsors
1 location
NCT07115927
pReOperative Dostarlimab and Novel Therapies in EndOmetrial Cancer
PHASE2
Not yet recruiting
40 participants
Started: Sep 30, 2025 · Completed: Jan 31, 2031
1 condition
2 sponsors
0 locations
NCT07201051
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
PHASE2
Not yet recruiting
400 participants
Started: Sep 26, 2025 · Completed: Nov 8, 2027
1 condition
1 sponsor
0 locations
NCT07168356
A Study to Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease
PHASE1
Recruiting
32 participants
Started: Sep 16, 2025 · Completed: Aug 18, 2026
1 condition
1 sponsor
1 location
NCT07121192
A Study to Assess the Immune Response and Safety of a Vaccine Against Influenza in Adults 18 Years of Age and Older
PHASE2
Recruiting
770 participants
Started: Aug 25, 2025 · Completed: May 15, 2026
1 condition
1 sponsor
22 locations
NCT07105709
Open-label Extension Study in Participants With Early Alzheimer's Disease
PHASE2
Recruiting
297 participants
Started: Aug 14, 2025 · Completed: Nov 24, 2028
1 condition
2 sponsors
5 locations
NCT07105722
A Trial to Evaluate the Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults 50 To 64 Years of Age
PHASE1
Recruiting
120 participants
Started: Aug 12, 2025 · Completed: Jun 18, 2026
1 condition
1 sponsor
4 locations
NCT07099898
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)
PHASE3
Recruiting
300 participants
Started: Aug 11, 2025 · Completed: Sep 11, 2028
1 condition
1 sponsor
14 locations
NCT07036159
A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months
PHASE2
Recruiting
238 participants
Started: Aug 6, 2025 · Completed: Apr 23, 2027
1 condition
1 sponsor
2 locations
NCT07092865
A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant
PHASE2
Recruiting
234 participants
Started: Aug 6, 2025 · Completed: Jul 16, 2027
1 condition
1 sponsor
2 locations
NCT07085702
A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of the GSK 4-component Strep A Vaccine With Aluminum Hydroxide (Alum) or AS37 in Healthy Young Adults
PHASE1
Recruiting
108 participants
Started: Jul 31, 2025 · Completed: Nov 30, 2026
1 condition
5 sponsors
2 locations
NCT06897527
A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With Recurrent or Advanced Endometrial Cancer (EC)
PHASE4
Not yet recruiting
100 participants
Started: Jul 15, 2025 · Completed: Jan 13, 2027
1 condition
1 sponsor
0 locations
NCT06995430
A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old)
PHASE3
Recruiting
312 participants
Started: Jul 7, 2025 · Completed: Dec 10, 2025
1 condition
1 sponsor
3 locations
NCT07017803
Molecular Epidemiology, Strains Genotyping of Multi-drug Resistant Tuberculosis Circulating in Central Africa Region
N/A
Not yet recruiting
460 participants
Started: Jul 1, 2025 · Completed: Jan 31, 2026
5 conditions
4 sponsors
0 locations
NCT06405230
Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Extracellular Vesicles (EVs), Patient-derived Organoid (PDOs)s and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)
PHASE1/PHASE2
Not yet recruiting
40 participants
Started: Jun 27, 2025 · Completed: Jun 27, 2029
1 condition
1 sponsor
1 location
NCT06961214
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
PHASE3
Recruiting
960 participants
Started: Jun 23, 2025 · Completed: Aug 21, 2029
1 condition
1 sponsor
1 location
NCT06959095
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)
PHASE3
Recruiting
981 participants
Started: Jun 20, 2025 · Completed: Aug 20, 2029
1 condition
1 sponsor
15 locations
NCT06990880
A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer
PHASE1/PHASE2
Recruiting
85 participants
Started: Jun 12, 2025 · Completed: Aug 9, 2028
1 condition
1 sponsor
5 locations
NCT06885034
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed
PHASE1/PHASE2
Recruiting
320 participants
Started: Jun 11, 2025 · Completed: Jun 23, 2028
1 condition
1 sponsor
12 locations
NCT06847867
A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome
PHASE2
Recruiting
80 participants
Started: Jun 5, 2025 · Completed: Mar 6, 2029
1 condition
1 sponsor
1 location
NCT06979323
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
PHASE3
Recruiting
150 participants
Started: Jun 3, 2025 · Completed: Feb 11, 2028
1 condition
1 sponsor
1 location
NCT06979518
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GSK3862995B Administered as a Single Dose to Healthy Participants of Chinese, Japanese, and European Ancestry
PHASE1
Not yet recruiting
30 participants
Started: May 20, 2025 · Completed: Apr 27, 2026
1 condition
1 sponsor
0 locations
NCT06806137
A Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Months After a First Dose at 12 to 15 Months of Age
PHASE3
Recruiting
600 participants
Started: May 15, 2025 · Completed: Apr 2, 2027
1 condition
1 sponsor
1 location
NCT06747845
Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy
PHASE2
Recruiting
68 participants
Started: May 7, 2025 · Completed: Jan 30, 2029
1 condition
4 sponsors
2 locations
NCT06911775
Eosinophil Subpopulations in Eosinophilic-associated Diseases
N/A
Not yet recruiting
160 participants
Started: Apr 30, 2025 · Completed: Dec 31, 2026
3 conditions
2 sponsors
0 locations
NCT06887933
A Trial to Evaluate the Safety of Niraparib Tablets in Adult Female Participants With Advanced or Relapsed Epithelial Ovarian Cancer
PHASE4
Not yet recruiting
67 participants
Started: Apr 22, 2025 · Completed: Jul 8, 2026
1 condition
1 sponsor
0 locations
NCT06855160
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age
PHASE3
Recruiting
900 participants
Started: Apr 17, 2025 · Completed: Dec 24, 2026
1 condition
1 sponsor
6 locations
NCT06920043
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
PHASE2
Recruiting
42 participants
Started: Apr 9, 2025 · Completed: Dec 31, 2027
1 condition
2 sponsors
35 locations
NCT06521567
A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
PHASE1/PHASE2
Active, not recruiting
95 participants
Started: Mar 6, 2025 · Completed: Jan 2, 2032
12 conditions
1 sponsor
18 locations
NCT06796907
A Study of GSK5733584 in Combination With Anti-cancer Therapies for Advanced Solid Tumors
PHASE1/PHASE2
Recruiting
392 participants
Started: Mar 4, 2025 · Completed: Apr 5, 2028
1 condition
1 sponsor
56 locations
NCT06702345
Clostridioides Difficile Controlled Human Infection Model
NA
Not yet recruiting
60 participants
Started: Mar 1, 2025 · Completed: Dec 31, 2026
3 conditions
5 sponsors
1 location
NCT06517875
Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis
PHASE2
Recruiting
56 participants
Started: Feb 28, 2025 · Completed: Nov 13, 2026
2 conditions
1 sponsor
12 locations
NCT06757244
DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic Cancer
PHASE2
Recruiting
35 participants
Started: Feb 18, 2025 · Completed: Feb 18, 2028
1 condition
2 sponsors
5 locations
NCT06567782
A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer
PHASE2
Recruiting
120 participants
Started: Feb 17, 2025 · Completed: Jun 15, 2028
1 condition
1 sponsor
12 locations
NCT06748053
A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma
PHASE2
Recruiting
300 participants
Started: Feb 10, 2025 · Completed: Jan 14, 2027
1 condition
1 sponsor
78 locations
NCT06740630
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age
PHASE3
Recruiting
1,840 participants
Started: Jan 10, 2025 · Completed: May 13, 2027
1 condition
1 sponsor
5 locations
NCT06679101
A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)
PHASE3
Recruiting
520 participants
Started: Dec 27, 2024 · Completed: Apr 6, 2032
2 conditions
1 sponsor
81 locations
NCT06763783
Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases
PHASE4
Enrolling by invitation
240 participants
Started: Dec 17, 2024 · Completed: Jun 30, 2034
9 conditions
2 sponsors
1 location
NCT06710847
A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
PHASE1/PHASE2
Recruiting
73 participants
Started: Dec 13, 2024 · Completed: Jun 16, 2028
5 conditions
2 sponsors
13 locations
NCT06716606
A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease
PHASE3
Recruiting
225 participants
Started: Dec 12, 2024 · Completed: Jan 8, 2030
1 condition
2 sponsors
6 locations
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